NR 507: Advanced Pathophysiology Midterm
Study online at https://quizlet.com/_7122fy
1. Asthma Chronic disease due to bronchoconstriction and an
excessive inflammatory response in the bronchi-
oles
2. What are 5 s/s of asthma coughing
wheezing
shortness of breath
rapid breathing
chest tightness
3. Pathophysiology of asthma (5) -airway inflammation, bronchial hyper-reactivity
and smooth muscle spasm
-excess mucus production and accumulation
-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
4. Bronchioles smaller passageways that originate from the
bronchi that become the alveoli
5. 3 layers of the bronchioles innermost layer
middle layer - lamina propria
outermost layer
6. lamina propria the middle layer of the bronchioles
7. structure of the lamina propria embedded with connective tissue cells and im-
mune cells
8. purpose of the lamina propria white blood cells are present to help protect the
airways
9.
, NR 507: Advanced Pathophysiology Midterm
Study online at https://quizlet.com/_7122fy
How does the lamina propria effect the WBCs protective feature goes into overdrive
the lungs in regards to asthma causing an inflammatory response that damages
host tissue
10. What does the innermost layer of the columnar epithelial ells and mucus producing
bronchioles contain goblet cells
11. What does the outermost layer of the smooth muscle cells
bronchioles contain
12. what does the outermost layer of the control the airways ability to constrict and dilate
bronchioles do
13. alveolar hyperinflation When air is unable to move out of the alveolar like
it should due to bronchial walls collapsing around
possible mucus plug thus trapping air inside
14. how does hyperinflation occur? the ongoing inflammatory process of asthma pro-
duces mucus and pus plug that the bronchial walls
collapse around
15. Effect of hyperinflation of the alveolar -expanded thorax and hypercapnia (retention of
CO2)
- respiratory acidosis
16. What are two anticholinergic drugs tiotropium and ipratropium
used for asthma
17. What do anticholinergics do in the These drugs block the effects of the parasympa-
lungs? thetic nervous system
- increasing bronchodilation
18. MOA of anticholinergic drugs for asth- the parasympathetic system is stimulated by the
ma vagal nerve to release acetylcholine which binds to
, NR 507: Advanced Pathophysiology Midterm
Study online at https://quizlet.com/_7122fy
the cholinergic receptors of the respiratory tract to
cause bronchial constriction = decreased airflow
- blocking the cholinergic receptors prevents
acetylcholine binding preventing the bronchial
constriction
19. bronchitis inflammation of the bronchial tubes
20. 3 characteristics of bronchitis bronchial inflammation
hypersecretion of mucus
chronic productive cough for at least 3 consecutive
months for at least 2 successive years
21. Perfusion The supply of oxygen to and removal of wastes
from the cells and tissues of the body as a result
of the flow of blood through the capillaries.
22. results of chronic bronchitis/ low per- cyanosis
fusion right to left shunting
chronic hypoxemia
23. Why is there cyanosis with chronic there is hypoxia due to unfavorable conditions for
bronchitis gas exchange
24. Right to left shunting when blood passes from the right ventricle
through the lungs and to the left ventricle without
perfusion
25. Causes of bronchitis -long term exposure to environmental irritants
-repeated episodes of acute infection (RSV infec-
tion in early infancy)
-Factors affecting gestational childhood lung de-
velopment (preterm birth)
Study online at https://quizlet.com/_7122fy
1. Asthma Chronic disease due to bronchoconstriction and an
excessive inflammatory response in the bronchi-
oles
2. What are 5 s/s of asthma coughing
wheezing
shortness of breath
rapid breathing
chest tightness
3. Pathophysiology of asthma (5) -airway inflammation, bronchial hyper-reactivity
and smooth muscle spasm
-excess mucus production and accumulation
-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
4. Bronchioles smaller passageways that originate from the
bronchi that become the alveoli
5. 3 layers of the bronchioles innermost layer
middle layer - lamina propria
outermost layer
6. lamina propria the middle layer of the bronchioles
7. structure of the lamina propria embedded with connective tissue cells and im-
mune cells
8. purpose of the lamina propria white blood cells are present to help protect the
airways
9.
, NR 507: Advanced Pathophysiology Midterm
Study online at https://quizlet.com/_7122fy
How does the lamina propria effect the WBCs protective feature goes into overdrive
the lungs in regards to asthma causing an inflammatory response that damages
host tissue
10. What does the innermost layer of the columnar epithelial ells and mucus producing
bronchioles contain goblet cells
11. What does the outermost layer of the smooth muscle cells
bronchioles contain
12. what does the outermost layer of the control the airways ability to constrict and dilate
bronchioles do
13. alveolar hyperinflation When air is unable to move out of the alveolar like
it should due to bronchial walls collapsing around
possible mucus plug thus trapping air inside
14. how does hyperinflation occur? the ongoing inflammatory process of asthma pro-
duces mucus and pus plug that the bronchial walls
collapse around
15. Effect of hyperinflation of the alveolar -expanded thorax and hypercapnia (retention of
CO2)
- respiratory acidosis
16. What are two anticholinergic drugs tiotropium and ipratropium
used for asthma
17. What do anticholinergics do in the These drugs block the effects of the parasympa-
lungs? thetic nervous system
- increasing bronchodilation
18. MOA of anticholinergic drugs for asth- the parasympathetic system is stimulated by the
ma vagal nerve to release acetylcholine which binds to
, NR 507: Advanced Pathophysiology Midterm
Study online at https://quizlet.com/_7122fy
the cholinergic receptors of the respiratory tract to
cause bronchial constriction = decreased airflow
- blocking the cholinergic receptors prevents
acetylcholine binding preventing the bronchial
constriction
19. bronchitis inflammation of the bronchial tubes
20. 3 characteristics of bronchitis bronchial inflammation
hypersecretion of mucus
chronic productive cough for at least 3 consecutive
months for at least 2 successive years
21. Perfusion The supply of oxygen to and removal of wastes
from the cells and tissues of the body as a result
of the flow of blood through the capillaries.
22. results of chronic bronchitis/ low per- cyanosis
fusion right to left shunting
chronic hypoxemia
23. Why is there cyanosis with chronic there is hypoxia due to unfavorable conditions for
bronchitis gas exchange
24. Right to left shunting when blood passes from the right ventricle
through the lungs and to the left ventricle without
perfusion
25. Causes of bronchitis -long term exposure to environmental irritants
-repeated episodes of acute infection (RSV infec-
tion in early infancy)
-Factors affecting gestational childhood lung de-
velopment (preterm birth)
