Verified by Experts
What is the most significant averse effect with opioid use is constipation? Correct
Answ_Constipation- reduced peristalsis and increased reabsorption of water
Adverse Effects of Opioids Correct Answ_-Sedation
-Urinary Retention- most common in spinal delivery medications
-Nausea and Vomiting- often resolves in about 3 days
-Pruritus- antihistamines can be used to help
-Myoclonus- twitching (alert provider bc it can lead to seizures)
Substance Misuse Correct Answ_People who misuse substances take medications for
purposes other than their intended use. For example using an opioid for anxiety
Substance Abuse Correct Answ_People who abuse drugs usually do not have a prescription.
They use this drug to get high
, Addiction Correct Answ_A primary, chronic, neurobiological disease with genetic,
psychosocial and environmental factors influencing its development and manifestation.
Characterizes by impaired control over drug use, compulsive use, continued use despite harm
and craving.
Tolerance Correct Answ_a state of adaption in which exposure to a drug induces changes
that result in diminution of one or more of the drugs effects over time. In the clinical setting
tolerance is not a significant problem
Physiological Dependence Correct Answ_Manifested by a withdrawal syndrome that can be
produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug of an
antagonist like naloxone.
Symptoms of withdrawal Correct Answ_fatigue, aches, sweating, nausea, vomiting,
depression and hallucinations
Route of Administration of Opiods Correct Answ_Transmucosal- rapid onset of analgesia,
expensive
Rectal-Thromboyctopenia, neutropenia or anorectal lesions can occur