Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Chapter 1-48

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Chapter 01: Drug Definitions, Standards, and Information Sources
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1. WhichmnamemidentifiesmamdrugmlistedmbymthemUSmFoodmDr
ugmAdministrationm(FDA)?
a. Bran
b. Nonproprietar
c. Official
d. Trademark
ANS:
Themofficialmnamemismthemnamemundermwhichmamdrugmismlistedmb
ymthem FDA.m Them brandm name,m orm trademark,m ism them namem give
nm tomamdrugmbymitsmmanufacturer.mThemnonproprietary,mormgener
ic,mnamemismprovidedmbymthemUnitedmStatesmAdoptedmNamesmC
ouncil.
CognitivemLevel:mKnowledge REF:m p.m9
OBJ:m1NAT:mNCLEXmClientmNeedsmCategory:mSafe,mEffectivemCa
remEnvironmentmTOP:m NursingmProcessmStep:mAssessment
CON:m
PatientmEducation




2. Whichmsourcemcontainsminformationmspecificmtomnutritionalmsupplements?
a. USPmDictionarymofmUSANm &mInternationalmDrugmNames
b. NaturalmMedicinesmComprehensivemDatabase
c. UnitedmStatesmPharmacopoeia/NationalmFormularym(USPmNF)
d. DrugmInteractionmFacts
ANS:m C
UnitedmStatesmPharmacopoeia/NationalmFormularymcontainsminformationmspecificmtomnutrition
almsupplements.mUSPmDictionarymofmUSANm&mInternationalmDrugmNamesmismamcompilationmofm
drugmnames,mpronunciationmguide,mandmpossiblemfuturemFDAmapprovedmdrugs;mitmdoesmnotmincl
udemnutritionalmsupplements.mNaturalmMedicinesmComprehensivemDatabasemcontains
evidence-
basedminformationmonmherbalmmedicinesmandmherbalmcombinationmproducts;mitmdoesmnotmincludem
informationmspecificmtomnutritionalmsupplements.mDrugmInteractionmFactsmcontainsmcomprehen
siveminformationmonmdrugminteractionmfacts;mitmdoesmnotmincludemnutritionalmsupplements.

DIF: CognitivemLevel:mKnowledge REF:m p.m4
OBJ:m3mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInt
egrity
TOP:m NursingmProcessmStep:mAssessment CON:m Nutritionm|mPatientmEducation

3. Whichmdrugmreferencemcontainsmdrugmmonographsmthatmdescribemallmdrugsminmamtherapeuticmclass?
a. DrugmFactsmandmComparisons

,TestmBankmFormClayton’smBasicmPharmacologymformNursesm19thmEdit 3
ion
b. DrugmInteractionmFacts
c. HandbookmonmInjectablemDrugs
d. Martindale—ThemCompletemDrugmReference

ANS:m A
DrugmFactsmandmComparisonsmcontainsmdrugmmonographsmthatmdescribemallmdrugsminma
therapeuticmclass.mMonographsmaremformattedmasmtablesmtomallowmcomparisonmofmsimila
m

rmproducts,mbrandmnames,mmanufacturers,mcostmindices,mandmavailablemdosagemformsmO
nlinemversionmismavailable.

DIF: CognitivemLevel:mKnowledge REF:m p.m4mTablem1.2
OBJ:mmm 3 NAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmIntegrity
TOP:m NursingmProcessmStep:mAssessment CON:m Safetym|mPatientmEducationm|mClinicalmJudgment

4. Whichmdrugmreferencemcontainsmmonographsmaboutmvirtuallymeverymsingle-
entitymdrugmavailableminmthemUnitedmStatesmandmdescribesmtherapeuticmusesmofmdrugs,mincludin
gmapprovedmandmunapprovedmuses?
a. Martindale:mThemCompletemDrugmReference
b. AHFSmDrugmInformation
c. DrugmReference
d. DrugmFactsmandmComparisons
ANS:m B
AHFSmDrugmInformationmcontainsmmonographsmaboutmvirtuallymeverymsingle-
entitymdrugmavailableminmthemUnitedmStatesmandmdescribesmtherapeuticmusesmofmdrugs,mincludingm
approvedmandmunapprovedmuses.

DIF: CognitivemLevel:mKnowledge REF:m p.m4mTablem1.2
OBJ:mmm 3 NAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmIntegrity
TOP:m NursingmProcessmStep:mPlanning CON:m Safetym|mPatientmEducationm|mClinicalmJudgment

5. Whichmonlinemdrugmreferencemmakesmavailablemtomhealthcaremprovidersmandmthempublicmams
tandard,mcomprehensive,mup-to-
datemlookmupmandmdownloadablemresourcemaboutmmedicines?
a. AmericanmDrugmIndex
b. AmericanmHospitalmFormulary
c. DailyMed
d. DrugmReference
ANS:m C
DailyMedmmakesmavailablemtomhealthcaremprovidersmandmthempublicmamstandard,mcomprehensiv
e,mup-to-
datemlookmupmandmdownloadablemresourcemaboutmmedicines.mThemAmericanmDrugmIndexmismnotm
appropriatemformpatientmuse.mThemAmericanmHospitalmFormularymismnotmappropriatemformpatie
ntmuse.mThemdrugmreferencemismnotmappropriatemformpatientmuse.

DIF: CognitivemLevel:mKnowledge REF:m p.m3m|mp.m4
OBJ:m3mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInt
egrity
TOP:m NursingmProcessmStep:mImplementation
CON:m Safetym|mPatientmEducationm|mClinicalmJudgment

6. WhichmlegislationmauthorizesmthemFDAmtomdeterminemthemsafetymofmamdrugmbeforemitsmmarketing?
a. FederalmFood,mDrug,mandmCosmeticmActm(1938)
b. DurhammHumphreymAmendmentm(1952)

, TestmBankmFormClayton’smBasicmPharmacologymformNursesm19thmEdit 4
ion
c. ControlledmSubstancesmActm(1970)
d. KefauvermHarrismDrugmAmendmentm(1962)
ANS:m A
ThemFederalmFood,mDrug,mandmCosmeticmActmofm1938mauthorizedmthemFDAmtomdeterminemthems
afetymofmallmdrugsmbeforemmarketing.mLatermamendmentsmandmactsmhelpedmtightenmFDAmcontro
lmandmensuremdrugmsafety.mThemDurhammHumphreymAmendmentmdefinesmthemkindsmofmdrugsmt
hatmcannotmbemusedmsafelymwithoutmmedicalmsupervisionmandmrestrictsmtheirmsalemtomprescriptio
nmbymamlicensedmpractitioner.mThemControlledmSubstancesmActmaddressesmonlymcontrolledmsubsta
ncesmandmtheirmcategorization.mThemKefauvermHarrismDrugmAmendmentmensuresmdrugmefficacym
andmgreatermdrugmsafety.mDrugmmanufacturersmaremrequiredmtomprovemtomthemFDAmthemeffective
nessmofmtheirmproductsmbeforemmarketingmthem.

DIF: CognitivemLevel:mKnowledge REF:mp.m5mTableml.3
OBJ:m 5
NAT:mNCLEXmClientmNeedsmCategory:mPhysiologicalmIntegrit
ymTOP:m NursingmProcessmStep:mAssessment
CON:m Safetym|mPatientmEducationm|mEvidencem|mHealthmCaremLaw

7. Whichmclassificationmdoesmmeperidinem(Demerol)mfallmunder?
a. I
b. II
c. III
d. IV
ANS:m B
Meperidinem(Demerol)mismamSchedulemIImdrug;mitmhasmamhighmpotentialmformabusemandmmaymlead
mtom
severempsychologicalmandmphysicalmdependence.mSchedulemImdrugsmhavemhighmpotentialmform
abusemandmnomrecognizedmmedicalmuse.mSchedulemIIImdrugsmhavemsomempotentialmformabuse.mUs
emmaymleadmtomlowmtommoderatemphysicalmdependencemormhighmpsychologicalmdependence.mSc
hedulemIVmdrugsmhavemlowmpotentialmformabuse.mUsemmaymleadmtomlimitedmphysicalmormpsychol
ogicalmdependence.

DIF: CognitivemLevel:mKnowledge REF:m p.m10
OBJ:m2mNAT:m NCLEXmClientmNeedsmCategory:mSafe,mEffectivemCa
remEnvironment
TOP:m NursingmProcessmStep:mAssessment CON:m PatientmEducationm|mAddictionm|mPain

8. WhichmactionmwouldmthemFDAmtakemtomexpeditemdrugmdevelopmentmandmapprovalmformanmoutbre
akmofmsmallpox?
a. Listmsmallpoxmasmamhealthmorphanmdisease.
b. Omitmthempreclinicalmresearchmphase.
c. Extendmthemclinicalmresearchmphase.
d. Fastmtrackmtheminvestigationalmdrug.
ANS:m D
OncemthemInvestigationalmNewmDrugmApplicationmhasmbeenmapproved,mthemdrugmcanmreceivemh
ighestmprioritymwithinmthemagency,mwhichmismcalledmfastmtracking.mAmsmallpoxmoutbreakmwould
mbecomemamprioritym concernminmthemworld.mOrphanmdiseasesmaremnotmresearchedminmamprioritym

manner.mPreclinicalmresearchmismnotmomitted.mExtendingmanymphasemofmthemresearchmwouldmme
anmamlongermtimemtomdevelopmamvaccine.mThemFDAmmustmensuremthatmallmphasesmofmthempreclinic
almandmclinicalmresearchmphasemhavembeenmcompletedminmamsafemmanner.

DIF: CognitivemLevel:mKnowledge REF:m p.m7 OBJ:m 5