https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING
m m m m m m
& TRANSFUSION PRACTICES 7TH EDITION B
m m m m m
Y DENISE M HARMENING
m m m
9780803668881 CHAPTER 1- m m
29 COMPLETE GUIDE
m m
,https://www.stuvia.com/
Chapter m1 mRBCsmandmPlateletmPreservation: mHistoricalmPerspectives mandmCurrentmTrends
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Which mmetabolic mpathway mismresponsible mformgeneratingm90% mof mthemATPmformthemRBC?
a. Pentose mphosphate mshunt c. Glycolysis
b. Luebering-Rapoportmshunt d.m Methemoglobin mreductase
2. Amunitmof mbloodmwasmreturned mtomthembloodmbank mbeforemitmwasmspiked.mApparently mthempatient’smIVmfailed.
mThe munitmofmbloodmwas moutsidemthembloodmbank mform35mminutes. mWhichmofmthe mstatements mbelowmismmost
maccurate?
a. Themunitmof mblood mshould mbemdiscarded mimmediately.
b. Themunitmof mblood mcan mbemreturned mto minventory.
c. Themunitmof mblood mmustmbemtransfused mwithin m4 mhoursmormbemdiscarded matmthemend mof mthatmtime.
d. Themunitmof mblood mmustmbemtransfused mwith m24 mhours.
3. Whatmismthemaverage mdiametermof mamplatelet?
a. 5 mto m10 mµm c. 1 mto m2 mµm
b. 2 mto m4 mµm d.m m 4 mto m6 mµm
4. In mthemnormalmhemoglobin-
oxygen mdissociationmcurve,mwhatmpercentagemofmoxygenmismreleased mto mthemtissuesmwhen mPO2m averagesm
40 mmmmHg?
a. 75% c. 100%
b. 25% d.m 50%
5. Whatmfactorsmaremknown mto minfluence mplateletmmetabolism mand mfunction?
a. Storage mtemperature c. Plateletmcount
b. InitialmpH d.m Allmof mthemabove
6. Which mofmthemfollowingmred mbloodmcellmmorphologiesmmaymbempresentmonmthemperipheralmbloodmsmearmasmamr
esultmof mlossmof mRBCmmembrane?
a. Spherocytes c. Burrmcells
b. Targetmcells d.m Schistocytes
7. Whatmdoesmthemtermmautologousmtransfusion mrefermto?
a. Amparentmdonatingmblood mformhismormhermchild
b. An mindividualmdonatingmblood mformamfriend
c. An mindividualmdonatingmblood mformamrelative
d. An mindividualmdonatingmblood mformhismormhermown mtransfusion
8. Whatmismthemprimary mfunction mof mhemoglobin?
a. Iron mmetabolism c. Oxygen mtransport
b. Porphyrin msynthesis d.m Signalmtransduction
9. Allmof mthemfollowingmareasmof mred mblood mcellmbiology maremcrucialmformnormalmerythrocyte msurvivalm except:
a. Cellularmmetabolism. c. Sitemof mthemABOmantigen mattachment.
b. RBCmmembrane. d.m Hemoglobin mstructure.
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m 10.m Whatmismthemcorrectmbiochemicalmcomposition mof mthemRBCmmembrane?
a. 52% mprotein,m40% mlipid,m8% mcarbohydrate
b. 40% mprotein,m8% mlipid,m52% mcarbohydrate
c. 8% mprotein,m52% mlipid,m40% mcarbohydrate
d. 8% mlipid,m40% mcarbohydrate, m52% mprotein
m 11.m Allmof mthemfollowingmbiochemicalmchangesmaremassociated mwith mlossmofmredmblood mcellmviability mupon mstorage
except:
a. Decreased mpH. c. Increased mATPmlevel.
b. Lossmof mred mblood mcellmfunction. d.m Decreased mglucose mconsumption.
m 12.m Which mred mblood mcellmpreservative mhasmamstoragemtimemof m35 mdays?
a. ACD c. AS-1
b. CPDA-1 d.m m CPD
m 13.m ThemRBCmmembrane mismrelatively mpermeable mto mallmof mthemfollowingmexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.m Water.
m 14.mWhatmpercentage mofmplateletsmismsequestered minmthemspleenmasmfunctionalmreservemaftermbeingmreleased mfro
mmthembonemmarrow?
a. 30% c. 10%
b. 50% d.m m 25%
m 15.m Whatmismthemmajormbiochemicalmconsideration min mplateletmstorage?
a. Glucose mmetabolism c. Production mof mcarbon mdioxide
b. Oxygen msupply d.m Regulation mof mpH
m 16.mWhatmwould mthemhemoglobin-
oxygen mdissociation mcurvemdepictmin mampatientmexhibitingmclinicalmsignsmof malkalosis?
a. Normal c. Shiftmto mthemright
b. Shiftmto mthemleft d.m None mof mthemabove
m 17.m Name mthemmain mlipid mcomponentsmof mamred mblood mcellmmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.m Glycophorin mA
m 18.m ThemABOmblood mgroupsmweremdiscovered min m1901 mby mwhom?
a. CharlesmDrew c. Loutitmand mMollison
b. KarlmLandsteiner d.m Edward mLindeman
m 19.mAmstandingmordermofmplateletsmwasmshippedmto myourmfacility mby myourmsupplier.mItmwasminadvertently mleftmin mt
hemcornermofmthemdepartmentmuntilmdiscoveredm36mhoursmlater.mWhatmwould mthemappropriatemaction mbemformth
emblood mbanker?
a. If mthemtemperature min mthembox mwasm22 m+/-
m2°Cmand mthe mplateletmswirlmseemedmOK, mitmwould mbemOK mtomacceptmthemunitmintominvento
ry.
b. Themplateletsmhavemfallenmoutsidemthemsupplier’smquality massurance.mThemunitmshouldmbe
mdiscardedmbecause mthempHmhas mprobably mdropped mtoomlowmandmplateletmactivationmhas m
been mcompromised.
c. If mthemtemperature mwasm1°Cmto m6°Cmand mthemplateletmswirlmseemed mOK,mitmwould mbemOKmto
This mstudy msourcemwas mdownloaded mby m100000826342158 mfrom mCourseHero.com mon m09-15-
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acceptmthemunitminto minventory.
d. If mthemplateletsmappearedmOKmand mpassed mthemplateletmswirlmtestmaftermbeingmplacedmon
mthe magitator, mthey mcould mbe maccepted minto mthe minventory.
m 20.m Which mmetabolic mpathway mpermitsmthemaccumulation mof m2,3 mdiphosphoglycerate m(2,3-DPG)?
a. Glycolysis c. Pentose mphosphate mshunt
b. Luebering-Rapoportmshunt d.m Methemoglobin mreductase
m 21.m Allmof mthemfollowingmaremconsistentmwithmam"shiftmto mthemright"mofmthemhemoglobin-oxygen mdissociation mcurve
except:
a. Increased m2,3-DPG.
b. 50% mO2 m saturation mto mtissues.
c. Decreased m2,3-DPG.
d. Decreased mhemoglobin maffinity mformO2.
m 22.m Whatmismthemnormalmplateletmcountmrangempermcubicmmillimeter?
a. 100 mto m350 c. 50,000 mto m200,000
b. 150,000 mto m350,000 d.m 350,000 mto m500,000
m 23.m Whatmcryoprotective magentmismadded mto mred mblood mcellsmupon mfreezing?
a. Dextrose c. Glycerol
b. Adsol d.m Allmof mthemabove
m 24.m If mplateletsmaremto mbemstored mform5 mdaysmon mamrotator,mwhatmismthemoptimalmstoragemtemperature?
a. 1°Cmto m6°C c. 35°Cmto m37°C
b. 20°Cmto m24°C d.m 1°Cmto m10°C
m 25.m Whatmrolemdo mplateletsmplay min mhemostasis?
a. Maintenance mof mvascularmintegrity
b. Initialmarrestmof mbleedingmby mplateletmplugmformation
c. Stabilization mof mthemhemostatic mplug
d. Allmof mthemabove
m 26.m Which mof mthemfollowingmbestmdescribesm"integral"mmembrane mproteins?
a. Reside matmthemcytoplasmic msurface mof mmembrane
b. Span mthementiremmembrane msurface
c. Formmthemred mblood mcellmcytoskeleton
d. Nonemof mthemabove
m 27.m Howmismstroma-freemhemoglobin msolution mprepared?
a. Outdated mred mblood mcellsmaremconcentrated, mand mstromamismremoved.
b. Outdated mred mblood mcellsmaremdiluted mwith msaline,mand mstromamismremoved.
c. Outdated mred mblood mcellsmaremlysed,mand mstromamismremoved.
d. Nonemof mthemabove
m 28.m Whatmismthemnormalmlifemspan mof man mRBC?
a. 100 mdays c. 120 mhours
b. 120 mdays d.m 2 mdays
m 29.m Regardingmlossmof mRBCmmembrane mdeformability, mallmof mthemfollowingmaremtruemexcept:
a. Increase min mATPmlevel.
b. Decrease min mATPmlevel.
This mstudy msourcemwas mdownloaded mby m100000826342158 mfrom mCourseHero.com mon m09-15-
2021 m17:54:15 mGMT m-05:00
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TEST BANK FOR MODERN BLOOD BANKING
m m m m m m
& TRANSFUSION PRACTICES 7TH EDITION B
m m m m m
Y DENISE M HARMENING
m m m
9780803668881 CHAPTER 1- m m
29 COMPLETE GUIDE
m m
,https://www.stuvia.com/
Chapter m1 mRBCsmandmPlateletmPreservation: mHistoricalmPerspectives mandmCurrentmTrends
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Which mmetabolic mpathway mismresponsible mformgeneratingm90% mof mthemATPmformthemRBC?
a. Pentose mphosphate mshunt c. Glycolysis
b. Luebering-Rapoportmshunt d.m Methemoglobin mreductase
2. Amunitmof mbloodmwasmreturned mtomthembloodmbank mbeforemitmwasmspiked.mApparently mthempatient’smIVmfailed.
mThe munitmofmbloodmwas moutsidemthembloodmbank mform35mminutes. mWhichmofmthe mstatements mbelowmismmost
maccurate?
a. Themunitmof mblood mshould mbemdiscarded mimmediately.
b. Themunitmof mblood mcan mbemreturned mto minventory.
c. Themunitmof mblood mmustmbemtransfused mwithin m4 mhoursmormbemdiscarded matmthemend mof mthatmtime.
d. Themunitmof mblood mmustmbemtransfused mwith m24 mhours.
3. Whatmismthemaverage mdiametermof mamplatelet?
a. 5 mto m10 mµm c. 1 mto m2 mµm
b. 2 mto m4 mµm d.m m 4 mto m6 mµm
4. In mthemnormalmhemoglobin-
oxygen mdissociationmcurve,mwhatmpercentagemofmoxygenmismreleased mto mthemtissuesmwhen mPO2m averagesm
40 mmmmHg?
a. 75% c. 100%
b. 25% d.m 50%
5. Whatmfactorsmaremknown mto minfluence mplateletmmetabolism mand mfunction?
a. Storage mtemperature c. Plateletmcount
b. InitialmpH d.m Allmof mthemabove
6. Which mofmthemfollowingmred mbloodmcellmmorphologiesmmaymbempresentmonmthemperipheralmbloodmsmearmasmamr
esultmof mlossmof mRBCmmembrane?
a. Spherocytes c. Burrmcells
b. Targetmcells d.m Schistocytes
7. Whatmdoesmthemtermmautologousmtransfusion mrefermto?
a. Amparentmdonatingmblood mformhismormhermchild
b. An mindividualmdonatingmblood mformamfriend
c. An mindividualmdonatingmblood mformamrelative
d. An mindividualmdonatingmblood mformhismormhermown mtransfusion
8. Whatmismthemprimary mfunction mof mhemoglobin?
a. Iron mmetabolism c. Oxygen mtransport
b. Porphyrin msynthesis d.m Signalmtransduction
9. Allmof mthemfollowingmareasmof mred mblood mcellmbiology maremcrucialmformnormalmerythrocyte msurvivalm except:
a. Cellularmmetabolism. c. Sitemof mthemABOmantigen mattachment.
b. RBCmmembrane. d.m Hemoglobin mstructure.
This mstudy msourcemwas mdownloaded mby m100000826342158 mfrom mCourseHero.com mon m09-15-
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m 10.m Whatmismthemcorrectmbiochemicalmcomposition mof mthemRBCmmembrane?
a. 52% mprotein,m40% mlipid,m8% mcarbohydrate
b. 40% mprotein,m8% mlipid,m52% mcarbohydrate
c. 8% mprotein,m52% mlipid,m40% mcarbohydrate
d. 8% mlipid,m40% mcarbohydrate, m52% mprotein
m 11.m Allmof mthemfollowingmbiochemicalmchangesmaremassociated mwith mlossmofmredmblood mcellmviability mupon mstorage
except:
a. Decreased mpH. c. Increased mATPmlevel.
b. Lossmof mred mblood mcellmfunction. d.m Decreased mglucose mconsumption.
m 12.m Which mred mblood mcellmpreservative mhasmamstoragemtimemof m35 mdays?
a. ACD c. AS-1
b. CPDA-1 d.m m CPD
m 13.m ThemRBCmmembrane mismrelatively mpermeable mto mallmof mthemfollowingmexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.m Water.
m 14.mWhatmpercentage mofmplateletsmismsequestered minmthemspleenmasmfunctionalmreservemaftermbeingmreleased mfro
mmthembonemmarrow?
a. 30% c. 10%
b. 50% d.m m 25%
m 15.m Whatmismthemmajormbiochemicalmconsideration min mplateletmstorage?
a. Glucose mmetabolism c. Production mof mcarbon mdioxide
b. Oxygen msupply d.m Regulation mof mpH
m 16.mWhatmwould mthemhemoglobin-
oxygen mdissociation mcurvemdepictmin mampatientmexhibitingmclinicalmsignsmof malkalosis?
a. Normal c. Shiftmto mthemright
b. Shiftmto mthemleft d.m None mof mthemabove
m 17.m Name mthemmain mlipid mcomponentsmof mamred mblood mcellmmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.m Glycophorin mA
m 18.m ThemABOmblood mgroupsmweremdiscovered min m1901 mby mwhom?
a. CharlesmDrew c. Loutitmand mMollison
b. KarlmLandsteiner d.m Edward mLindeman
m 19.mAmstandingmordermofmplateletsmwasmshippedmto myourmfacility mby myourmsupplier.mItmwasminadvertently mleftmin mt
hemcornermofmthemdepartmentmuntilmdiscoveredm36mhoursmlater.mWhatmwould mthemappropriatemaction mbemformth
emblood mbanker?
a. If mthemtemperature min mthembox mwasm22 m+/-
m2°Cmand mthe mplateletmswirlmseemedmOK, mitmwould mbemOK mtomacceptmthemunitmintominvento
ry.
b. Themplateletsmhavemfallenmoutsidemthemsupplier’smquality massurance.mThemunitmshouldmbe
mdiscardedmbecause mthempHmhas mprobably mdropped mtoomlowmandmplateletmactivationmhas m
been mcompromised.
c. If mthemtemperature mwasm1°Cmto m6°Cmand mthemplateletmswirlmseemed mOK,mitmwould mbemOKmto
This mstudy msourcemwas mdownloaded mby m100000826342158 mfrom mCourseHero.com mon m09-15-
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acceptmthemunitminto minventory.
d. If mthemplateletsmappearedmOKmand mpassed mthemplateletmswirlmtestmaftermbeingmplacedmon
mthe magitator, mthey mcould mbe maccepted minto mthe minventory.
m 20.m Which mmetabolic mpathway mpermitsmthemaccumulation mof m2,3 mdiphosphoglycerate m(2,3-DPG)?
a. Glycolysis c. Pentose mphosphate mshunt
b. Luebering-Rapoportmshunt d.m Methemoglobin mreductase
m 21.m Allmof mthemfollowingmaremconsistentmwithmam"shiftmto mthemright"mofmthemhemoglobin-oxygen mdissociation mcurve
except:
a. Increased m2,3-DPG.
b. 50% mO2 m saturation mto mtissues.
c. Decreased m2,3-DPG.
d. Decreased mhemoglobin maffinity mformO2.
m 22.m Whatmismthemnormalmplateletmcountmrangempermcubicmmillimeter?
a. 100 mto m350 c. 50,000 mto m200,000
b. 150,000 mto m350,000 d.m 350,000 mto m500,000
m 23.m Whatmcryoprotective magentmismadded mto mred mblood mcellsmupon mfreezing?
a. Dextrose c. Glycerol
b. Adsol d.m Allmof mthemabove
m 24.m If mplateletsmaremto mbemstored mform5 mdaysmon mamrotator,mwhatmismthemoptimalmstoragemtemperature?
a. 1°Cmto m6°C c. 35°Cmto m37°C
b. 20°Cmto m24°C d.m 1°Cmto m10°C
m 25.m Whatmrolemdo mplateletsmplay min mhemostasis?
a. Maintenance mof mvascularmintegrity
b. Initialmarrestmof mbleedingmby mplateletmplugmformation
c. Stabilization mof mthemhemostatic mplug
d. Allmof mthemabove
m 26.m Which mof mthemfollowingmbestmdescribesm"integral"mmembrane mproteins?
a. Reside matmthemcytoplasmic msurface mof mmembrane
b. Span mthementiremmembrane msurface
c. Formmthemred mblood mcellmcytoskeleton
d. Nonemof mthemabove
m 27.m Howmismstroma-freemhemoglobin msolution mprepared?
a. Outdated mred mblood mcellsmaremconcentrated, mand mstromamismremoved.
b. Outdated mred mblood mcellsmaremdiluted mwith msaline,mand mstromamismremoved.
c. Outdated mred mblood mcellsmaremlysed,mand mstromamismremoved.
d. Nonemof mthemabove
m 28.m Whatmismthemnormalmlifemspan mof man mRBC?
a. 100 mdays c. 120 mhours
b. 120 mdays d.m 2 mdays
m 29.m Regardingmlossmof mRBCmmembrane mdeformability, mallmof mthemfollowingmaremtruemexcept:
a. Increase min mATPmlevel.
b. Decrease min mATPmlevel.
This mstudy msourcemwas mdownloaded mby m100000826342158 mfrom mCourseHero.com mon m09-15-
2021 m17:54:15 mGMT m-05:00
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