NURS 660 PSYCHOPHARM (EXAM 1-WITH 100% VERIFIED
SOLUTIONS-2025
Typical antipsychotics - (answer)What class of antipsychotic are these Neuroleptics,
Conventional, First Generation, Dopamine Receptor Antagonists?
Atypical Antipsychotics - (answer)What class of antipsychotic are these Second Generation,
Serotonin-Dopamine Receptor Antagonists
Dopamine D2 receptor - (answer)This receptor has the benefit of reducing positive symptoms.
Possible side effects include: Parkinsonism, akathisia, tardive dyskinesia, endocrine effects such
as prolactin secretion, menstrual changes and sexual dysfunction.
主题的中文文章？
Serotonin 5-H2a receptor - (answer)This receptor has the benefit of reducing EPS
Possible side effects: Sexual dysfunction
Serotonin 5HT2c receptor - (answer)The benefit of this receptor is unknown
Side effect is weight gain
Histamine H-1 receptor - (answer)The benefit of this receptor is sedation
Side effects are sedation, increased appetite, weight gain and hypotension
Muscarinic cholinergic receptors - (answer)The benefit of the receptor is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth, constipation, urinary
retention, tachycardia and memory dysfunction.
a1-adrenergic receptors - (answer)Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex tachycardia.
, a2-adrenergic receptors - (answer)Benefit of receptor unknown
Side effects are drug interactions
D2-Agonist actions? - (answer)What makes an antipsychotic conventional?
D2 antagonist/First generation antipsychotics/Conventional antipsychotics/Typical
antipsychotics - (answer)These antipsychotics share the primary pharmacological property of D2
antagonism, which is responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
Conventional Antipsychotic - (answer)These drugs have pharmacological properties in addition
to D2 antagonism, they block muscarinic cholinergic receptors, histamine h-1 receptors and/or
a1-adrenergic receptors.
主题的中文文章？
60-80% - (answer)Antipsychotic properties happen when how much of the D2 receptor is
blocked?
80% - (answer)The degree of binding in the mesolimbic pathway needed for antipsychotic
effects is?
extrapyramidal side effects - (answer)When greater that 80% of D2 receptors are occupied in the
dorsal striatum what happens?
Pituitary gland - (answer)Which organ is associated with hyperprolactinemia?
Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine, Promazine and Triflupromazine)
- (answer)These group of Phenothiazine medications are low/medium potency agents, with high
sedation, medium anti-muscarinic effects, and medium extrapyramidal side effects.
Piperidine (Mesoridazine, Pericyazine, Pipotiazine, and Thiordiazine) - (answer)This group of
Phenothiazine medications are low-medium potency agents, with medium sedation, high
antimuscarinic effects, and low extrapyramidal side effects.
SOLUTIONS-2025
Typical antipsychotics - (answer)What class of antipsychotic are these Neuroleptics,
Conventional, First Generation, Dopamine Receptor Antagonists?
Atypical Antipsychotics - (answer)What class of antipsychotic are these Second Generation,
Serotonin-Dopamine Receptor Antagonists
Dopamine D2 receptor - (answer)This receptor has the benefit of reducing positive symptoms.
Possible side effects include: Parkinsonism, akathisia, tardive dyskinesia, endocrine effects such
as prolactin secretion, menstrual changes and sexual dysfunction.
主题的中文文章？
Serotonin 5-H2a receptor - (answer)This receptor has the benefit of reducing EPS
Possible side effects: Sexual dysfunction
Serotonin 5HT2c receptor - (answer)The benefit of this receptor is unknown
Side effect is weight gain
Histamine H-1 receptor - (answer)The benefit of this receptor is sedation
Side effects are sedation, increased appetite, weight gain and hypotension
Muscarinic cholinergic receptors - (answer)The benefit of the receptor is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth, constipation, urinary
retention, tachycardia and memory dysfunction.
a1-adrenergic receptors - (answer)Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex tachycardia.
, a2-adrenergic receptors - (answer)Benefit of receptor unknown
Side effects are drug interactions
D2-Agonist actions? - (answer)What makes an antipsychotic conventional?
D2 antagonist/First generation antipsychotics/Conventional antipsychotics/Typical
antipsychotics - (answer)These antipsychotics share the primary pharmacological property of D2
antagonism, which is responsible not only for their antipsychotic efficacy, but also for many of
their side effects.
Conventional Antipsychotic - (answer)These drugs have pharmacological properties in addition
to D2 antagonism, they block muscarinic cholinergic receptors, histamine h-1 receptors and/or
a1-adrenergic receptors.
主题的中文文章？
60-80% - (answer)Antipsychotic properties happen when how much of the D2 receptor is
blocked?
80% - (answer)The degree of binding in the mesolimbic pathway needed for antipsychotic
effects is?
extrapyramidal side effects - (answer)When greater that 80% of D2 receptors are occupied in the
dorsal striatum what happens?
Pituitary gland - (answer)Which organ is associated with hyperprolactinemia?
Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine, Promazine and Triflupromazine)
- (answer)These group of Phenothiazine medications are low/medium potency agents, with high
sedation, medium anti-muscarinic effects, and medium extrapyramidal side effects.
Piperidine (Mesoridazine, Pericyazine, Pipotiazine, and Thiordiazine) - (answer)This group of
Phenothiazine medications are low-medium potency agents, with medium sedation, high
antimuscarinic effects, and low extrapyramidal side effects.
