Solid Oral Dosage Form Notes

🫑
Solid Oral Dosage Forms
Created @February 3, 2025 3:53 PM

Class Molecules to Medicine

Disperse System

Two-phase system where the insoluble (Solid particles) or immiscible
dispersed (Liquid droplets) phase is distributed through continuous phase




Advantages of Solid Dosage Forms

Convenient and clean

Economic- Light and compact

Stable- Dry

Accurate dose

Possible controlled release

Can mask taste

Flexibility in formulation



Disadvantages of Solid Dosage Forms

Difficult to swallow

Fixed dose

Quantity of the drug difficult to adjust

Difficult for liquid drugs



Solid Oral Dosage Forms 1

, Tablets

Single dose of one or more active substances

A result of compressing particles all w/ the same volume

Oral administration

Shapes from 50mg→500mg

Properties

Strength
Able to withstand shock from manufacturing, packaging, shipping,
dispensing and use

Efficacy
Drug content needs to be bioavailable, release must be easily copied
to other formulations

Safety

Needs to be chemically and physically stable

Same weight

Same amount of drug




Tablet Types

Uncoated/coated

Orodispersible (Dissolves in saliva)

Carbonated

Chewable

Buccal




Solid Oral Dosage Forms 2