ATI Pharmacology Proctored Exam: Diverse, Expert-
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A nurse is caring for a group of clients who are not protected against Varicella. The nurse should
prepare to administer the Varicella vaccine at this time to which of the following clients?
A. 24-year-old woman in the third trimester of pregnancy
B. 12-year-old child who has a severe allergy to neomycin
C. 2-month-old infant who has no health problems
D. 32-year-old man who has essential hypertension - CORRECT ANSWER- -D (A 32-year-old man
who has essential hypertension and did not receive two doses of varicella vaccine earlier in
life should be immunized. Essential hypertension is not a contraindication for this vaccine)
A nurse is caring for a client who has breast cancer and asks why she is receiving a combination
therapy of Cyclophosphamide, Methotrexate, and Fluorouracil. The response by the nurse
should include that combination chemotherapy is used to do which of the following? (Select all
that apply.)
A. Decrease medication resistance
B. Attack cancer cells at different stages of cell growth
C. Block chemotherapy agent from entering healthy cells
D. Stimulate immune system
E. Decrease injury to normal body cells - CORRECT ANSWER- -a, b, e
(A.medication resistance is decreased with combination therapy because the chance of
developing resistance to several medication is less than to only one medication.
,B. Each medication kills cancer cells at a different stage of growth. A combination of
medications can kill more cancer cells than only one medication.
E. Injury to normal body cells can be decreased by combination therapy because the
medications used have different toxicities)
A nurse is caring for a client who is being treated with Interferon alfa-2b for Malignant
Melanoma. For which of the following adverse effects should the nurse monitor? (Select all that
apply.)
A. Tinnitus
B. Muscle aches
C. Peripheral neuropathy
D. Bone loss
E. Depression - CORRECT ANSWER- -b, c, e
(B.muscle aches and other flu-like manifestations are common adverse effects of interferon alfa-
2b. Acetaminophen may be prescribed to relieve these manifestations.
C. Peripheral neuropathy, dizziness, and fatigue are CNS effects that can occur when taking
interferon alfa-2b. These should be reported to the provider, and the nurse should teach the
client to prevent injury from falls.
E. Depression and mental status changes can occur with interferon alfa-2b treatment. The
nurse should assess the client for suicidal thoughts.)
A nurse is caring for a client who receives Rituximab to treat Non-hodgkin's Leukemia and who
asks the nurse how Rituximab works. Which of the following should the nurse include?
, A. Blocks hormone receptors
B. Increases immune response
C. Binds with specific antigens on tumor cells
D. Stops DNA replication during cell division - CORRECT ANSWER- -C (Rituximab is a monoclonal
antibody that binds to specific antigens on B-lymphocytes and then destroying cancer cells.)
A nurse is preparing to administer Cyclophosphamide IV to a client who has Hodgkin's disease.
Which of the following medications should the nurse expect to administer concurrently with the
chemotherapy to prevent an adverse effect of Cyclophosphamide?
A. Uroprotectant agent, such as mesna
B. Opioid, such as morphine
C. Loop diuretic, such as furosemide
D. H1 receptor antagonist, such as diphenhydramine - CORRECT ANSWER- -A (Mesna is a
uroprotectant agent that can help prevent hemorrhagic cystitis when administered IV with a
nitrogen mustard chemotherapy medication)
A nurse is preparing to administer Leucovorin to a client who has cancer and is receiving
chemotherapy with Methotrexate. Which of the following responses should the nurse use when
the client asks why Leucovorin is being given?
A. "Leucovorin reduces the risk of a transfusion reaction from methotrexate."
B. "Leucovorin increases platelet production and prevents bleeding."
C. "Leucovorin potentiates the cytotoxic effects of methotrexate."
D. "Leucovorin protects healthy cells from methotrexate's toxic effect." - CORRECT ANSWER- -D
(Leucovorin, a folic acid derivative and an antagonist to methotrexate, is given within 12 hr of
high doses of methotrexate to protect healthy cells from the toxic effects of methotrexate)
A nurse is teaching a client who has breast cancer about Tamoxifen. Which of the following
adverse effects of tamoxifen should the nurse discuss with the client?
Verified Questions and Solutions from Premier
Scholars Worldwide
A nurse is caring for a group of clients who are not protected against Varicella. The nurse should
prepare to administer the Varicella vaccine at this time to which of the following clients?
A. 24-year-old woman in the third trimester of pregnancy
B. 12-year-old child who has a severe allergy to neomycin
C. 2-month-old infant who has no health problems
D. 32-year-old man who has essential hypertension - CORRECT ANSWER- -D (A 32-year-old man
who has essential hypertension and did not receive two doses of varicella vaccine earlier in
life should be immunized. Essential hypertension is not a contraindication for this vaccine)
A nurse is caring for a client who has breast cancer and asks why she is receiving a combination
therapy of Cyclophosphamide, Methotrexate, and Fluorouracil. The response by the nurse
should include that combination chemotherapy is used to do which of the following? (Select all
that apply.)
A. Decrease medication resistance
B. Attack cancer cells at different stages of cell growth
C. Block chemotherapy agent from entering healthy cells
D. Stimulate immune system
E. Decrease injury to normal body cells - CORRECT ANSWER- -a, b, e
(A.medication resistance is decreased with combination therapy because the chance of
developing resistance to several medication is less than to only one medication.
,B. Each medication kills cancer cells at a different stage of growth. A combination of
medications can kill more cancer cells than only one medication.
E. Injury to normal body cells can be decreased by combination therapy because the
medications used have different toxicities)
A nurse is caring for a client who is being treated with Interferon alfa-2b for Malignant
Melanoma. For which of the following adverse effects should the nurse monitor? (Select all that
apply.)
A. Tinnitus
B. Muscle aches
C. Peripheral neuropathy
D. Bone loss
E. Depression - CORRECT ANSWER- -b, c, e
(B.muscle aches and other flu-like manifestations are common adverse effects of interferon alfa-
2b. Acetaminophen may be prescribed to relieve these manifestations.
C. Peripheral neuropathy, dizziness, and fatigue are CNS effects that can occur when taking
interferon alfa-2b. These should be reported to the provider, and the nurse should teach the
client to prevent injury from falls.
E. Depression and mental status changes can occur with interferon alfa-2b treatment. The
nurse should assess the client for suicidal thoughts.)
A nurse is caring for a client who receives Rituximab to treat Non-hodgkin's Leukemia and who
asks the nurse how Rituximab works. Which of the following should the nurse include?
, A. Blocks hormone receptors
B. Increases immune response
C. Binds with specific antigens on tumor cells
D. Stops DNA replication during cell division - CORRECT ANSWER- -C (Rituximab is a monoclonal
antibody that binds to specific antigens on B-lymphocytes and then destroying cancer cells.)
A nurse is preparing to administer Cyclophosphamide IV to a client who has Hodgkin's disease.
Which of the following medications should the nurse expect to administer concurrently with the
chemotherapy to prevent an adverse effect of Cyclophosphamide?
A. Uroprotectant agent, such as mesna
B. Opioid, such as morphine
C. Loop diuretic, such as furosemide
D. H1 receptor antagonist, such as diphenhydramine - CORRECT ANSWER- -A (Mesna is a
uroprotectant agent that can help prevent hemorrhagic cystitis when administered IV with a
nitrogen mustard chemotherapy medication)
A nurse is preparing to administer Leucovorin to a client who has cancer and is receiving
chemotherapy with Methotrexate. Which of the following responses should the nurse use when
the client asks why Leucovorin is being given?
A. "Leucovorin reduces the risk of a transfusion reaction from methotrexate."
B. "Leucovorin increases platelet production and prevents bleeding."
C. "Leucovorin potentiates the cytotoxic effects of methotrexate."
D. "Leucovorin protects healthy cells from methotrexate's toxic effect." - CORRECT ANSWER- -D
(Leucovorin, a folic acid derivative and an antagonist to methotrexate, is given within 12 hr of
high doses of methotrexate to protect healthy cells from the toxic effects of methotrexate)
A nurse is teaching a client who has breast cancer about Tamoxifen. Which of the following
adverse effects of tamoxifen should the nurse discuss with the client?
