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Organic Chemistry
Created @October 23, 2024 10:36 AM
Class Pharmaceutical Chemistry
Ions contain more electrons/ electrons as they are charged
1 atomic mass= 1.67 x 10 (-27) kg/ 1 Dalton
Isotopes
Same element containing a different amount of neutrons
Ionic Bonding
Bond between metals and non-metals, some electrostatic attractions present
Cation-
Organic Chemistry 1
, Positively charged ions/ metals losing electrons
Anion
Negatively charged ion/ non metals gaining electrons
Functional Group:
Meth1 carbon
Eth2 carbons
Prop3 carbons
But4 carbons
Pent5 carbons
Hex6 carbons
Number the carbons in the longest carbon chain
SPOT THE FUNCTIONAL GROUP
Functional Groups Can Affect
Acid/base propertiese ionisation state
Water and lipid solubility
Stereochemistry e.g stereoisomerism, 3D structures
All of the above can affect absorption/ distribution, metabolism and
excretion
Toxicity can also be generated
Isomers
Substances containing the same molecular formular but atoms are re-
arranged
Organic Chemistry 2
Organic Chemistry
Created @October 23, 2024 10:36 AM
Class Pharmaceutical Chemistry
Ions contain more electrons/ electrons as they are charged
1 atomic mass= 1.67 x 10 (-27) kg/ 1 Dalton
Isotopes
Same element containing a different amount of neutrons
Ionic Bonding
Bond between metals and non-metals, some electrostatic attractions present
Cation-
Organic Chemistry 1
, Positively charged ions/ metals losing electrons
Anion
Negatively charged ion/ non metals gaining electrons
Functional Group:
Meth1 carbon
Eth2 carbons
Prop3 carbons
But4 carbons
Pent5 carbons
Hex6 carbons
Number the carbons in the longest carbon chain
SPOT THE FUNCTIONAL GROUP
Functional Groups Can Affect
Acid/base propertiese ionisation state
Water and lipid solubility
Stereochemistry e.g stereoisomerism, 3D structures
All of the above can affect absorption/ distribution, metabolism and
excretion
Toxicity can also be generated
Isomers
Substances containing the same molecular formular but atoms are re-
arranged
Organic Chemistry 2
