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Chemical Modification and the
Effect of pH
Created @November 3, 2024 6:03 PM
Class Molecules to Medicine
H0- Hydrophilic Groups
Carboxylic groups are polar
Aromatic groups are non polar
Hydroxyl groups are polar
Antilog- 10 to the power of pH
Manipulating the Solubility of a Drug
Use of co-solvents (Selecting the right solvent)
Salt formation
Adding solubilising groups to the structure
Using effects of pH
Using dosage forms
Incorporating Water Solubilising Groups
Types of group added
If reaction is reversible or irreversible
Introducing chemical routes
Chemical Modification and the Effect of pH 1
Chemical Modification and the
Effect of pH
Created @November 3, 2024 6:03 PM
Class Molecules to Medicine
H0- Hydrophilic Groups
Carboxylic groups are polar
Aromatic groups are non polar
Hydroxyl groups are polar
Antilog- 10 to the power of pH
Manipulating the Solubility of a Drug
Use of co-solvents (Selecting the right solvent)
Salt formation
Adding solubilising groups to the structure
Using effects of pH
Using dosage forms
Incorporating Water Solubilising Groups
Types of group added
If reaction is reversible or irreversible
Introducing chemical routes
Chemical Modification and the Effect of pH 1
