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Pharmacotherapeutics for Advanced Practice Nurse Prescribers

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Pharmacotherapeutics for Advanced Practice Nurse Prescribers 2025 Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT: 1) Reducing the dosage of one of the drugs 2) Scheduling their administration at different times 3) Prescribing a third drug to counteract the adverse reaction of the combination 4) Reducing the dosage of both drugs - ansPrescribing a third drug to counteract the adverse reaction of the combination An example of a first-dose reaction that may occur includes: 1. Orthostatic hypotension that does not occur with repeated doses 2. Purple glove syndrome with phenytoin use 3. Hemolytic anemia from ceftriaxone use 4. Contact dermatitis from neomycin use - ansOrthostatic hypotension that does not occur with repeated doses Are drugs that are disgnedated Schedule II by the DEA refillable - ansNo. A new prescription needs to be written Are there known drug reactions with Beclomethasone (QVAR) - ansNo Azithromycin doing requires that the first day's doing be twice those of the other four day; This is considered a loading does. What is a loading dose? - ansRapidly actives drug levels in the therapeutic range Based on the patients below, who is at high risk for experiencing an adverse drug reaction? 1) 32-year old male 2) 22- year told female 3) 3 month old female 4)48 year old male - ans3 month old Cost-effectiveness analysis compares two or more treatments or programs that are: - ansnot necessarily therapeutically equivalent Digoxin levels need to be monitored closely when the following medication is started: 1. Loratadine 2. Diphenhydramine 3. Ipratropium 4. Albuterol - ansAlbuterol

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Pharmacotherapeutics for Advanced Practice Nurse Prescribers 2025

Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT:
1) Reducing the dosage of one of the drugs

2) Scheduling their administration at different times

3) Prescribing a third drug to counteract the adverse reaction of the combination

4) Reducing the dosage of both drugs - ansPrescribing a third drug to counteract the adverse reaction of the
combination



An example of a first-dose reaction that may occur includes:

1. Orthostatic hypotension that does not occur with repeated doses

2. Purple glove syndrome with phenytoin use

3. Hemolytic anemia from ceftriaxone use

4. Contact dermatitis from neomycin use - ansOrthostatic hypotension that does not occur with repeated doses



Are drugs that are disgnedated Schedule II by the DEA refillable - ansNo. A new prescription needs to be
written



Are there known drug reactions with Beclomethasone (QVAR) - ansNo



Azithromycin doing requires that the first day's doing be twice those of the other four day; This is considered a
loading does. What is a loading dose? - ansRapidly actives drug levels in the therapeutic range



Based on the patients below, who is at high risk for experiencing an adverse drug reaction?

1) 32-year old male

2) 22- year told female

3) 3 month old female

4)48 year old male - ans3 month old

, Cost-effectiveness analysis compares two or more treatments or programs that are: - ansnot necessarily
therapeutically equivalent



Digoxin levels need to be monitored closely when the following medication is started:

1. Loratadine

2. Diphenhydramine

3. Ipratropium

4. Albuterol - ansAlbuterol



Digoxin may cause a type A adverse drug reaction due to:

1. Idiosyncratic effects

2. Its narrow therapeutic index

3. Being a teratogen

4. Being a carcinogen - ansIts narrow therapeutic index



Drug administration via IV:

1) need to be lipid soluble in order to absorb easily

2) Begin distribution in the body immediately

3) Are easily absorbed if they are nonionized

4) May use pinocytosis to be absorbed - ansAre easily absorbed if they are nonionized



Drug antagonism is best defined as an effect of a drug that:

1. Leads to major physiological and psychological dependence

2. Is modified by the concurrent administration of another drug

3. Cannot be metabolized before another dose is administered

4. Leads to a decreased physiological response when combined with another drug - ansIs modified by the
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