BMS 528 Quiz Lecture 10 Question and
answers correctly solved
Receptor X and Receptor Y both bind Ligand Z. Receptor X binds to Ligand Z
with a Kd = 40 μM, while Receptor Y binds to Ligand Z with a Kd = 80
μM.Which receptor has the HIGHER affinity for Ligand Z?
A. Receptor X
B. Receptor Y
C. Both the same
D. Cannot tell with this information - correct answer ✔A. Receptor X
cAMP is a second messenger molecule that function to do what?
A. Inhibit protein kinase A
B. Activate protein kinase A
C. Inhibit phospholipase C
D. Activate phospholipase C - correct answer ✔B. Activate protein kinase A
G protein-coupled receptors have how many transmembrane domains?
A. 1
B. 5
C. 7
D. 10 - correct answer ✔C. 7
, G protein coupled receptors MUST dimerize in order to function.
A. True
B. False - correct answer ✔B. False
G proteins are heterotrimer of α, β and γ subunits. Which subunit binds to
nucleotides?
A. αsubunit
B. βsubunit
C. γsubunit - correct answer ✔A. αsubunit
What does a GTPase do? (Select all that apply)
A. Bind to guanine nucleotides
B. Hydrolyze nucleotide triphosphates
C. Function as part of signaling pathways
D. Phosphorylate other proteins - correct answer ✔A. Bind to guanine
nucleotides
B. Hydrolyze nucleotide triphosphates
C. Function as part of signaling pathways
Isoprenylation is a post-translational modification of protein. What is added to
proteins that are "isoprenylated"?
A. A phosphate group
B. A methyl group
answers correctly solved
Receptor X and Receptor Y both bind Ligand Z. Receptor X binds to Ligand Z
with a Kd = 40 μM, while Receptor Y binds to Ligand Z with a Kd = 80
μM.Which receptor has the HIGHER affinity for Ligand Z?
A. Receptor X
B. Receptor Y
C. Both the same
D. Cannot tell with this information - correct answer ✔A. Receptor X
cAMP is a second messenger molecule that function to do what?
A. Inhibit protein kinase A
B. Activate protein kinase A
C. Inhibit phospholipase C
D. Activate phospholipase C - correct answer ✔B. Activate protein kinase A
G protein-coupled receptors have how many transmembrane domains?
A. 1
B. 5
C. 7
D. 10 - correct answer ✔C. 7
, G protein coupled receptors MUST dimerize in order to function.
A. True
B. False - correct answer ✔B. False
G proteins are heterotrimer of α, β and γ subunits. Which subunit binds to
nucleotides?
A. αsubunit
B. βsubunit
C. γsubunit - correct answer ✔A. αsubunit
What does a GTPase do? (Select all that apply)
A. Bind to guanine nucleotides
B. Hydrolyze nucleotide triphosphates
C. Function as part of signaling pathways
D. Phosphorylate other proteins - correct answer ✔A. Bind to guanine
nucleotides
B. Hydrolyze nucleotide triphosphates
C. Function as part of signaling pathways
Isoprenylation is a post-translational modification of protein. What is added to
proteins that are "isoprenylated"?
A. A phosphate group
B. A methyl group
