1. Why do many medications lack pediatric There is lack of evi-
dosing information in their drug labeling dence-based literature on
the safe and effective use of
medications in children
2. Why are neonates at greater risk for toxicity Protein binding is decreased
with highly protein-bound drugs in neonates increasing the
amount of free drug avail-
able
3. At what age are adult levels of renal function 12 months
achieved
4. What is the most accurate device for mea- An oral syringe
suring a 2.5mL dose for a child
5. How do you help prevent medication errors Write out the term daily
6. In pediatric patients gastric acidity does not 2 years
reach adult values for
7. Nalidixic acid may cause in chil- cartilage erosion
dren
8. Altered absorption of drugs in the elderly Delayed
may result in drug response
9. You have an elderly patient taking war- You will need to decrease
farin. You add another protein binding drug. dose of warfarin
Which of the following statements is cor-
rect?
10. In elderly, proper index of renal function is Glomerular filtration rate
(GFR)
11. List that identifies drugs with high likeli- of the penicillin's
hood of cause adverse effects in elderly involve inhibition of
12. Primary mechanism of antibacterial action
,Beers list
, Cell wall synthesis by bind-
ing and inactivating penicillin
binding proteins (PBPs)
13. Which statement about vancomycin is accu- Increases bacterial cell wall
rate permeability and inhibits
RNA synthesis
14. The mechanism of action of the tetracy- Inhibiting protein synthesis
clines involves
15. Mechanism of action of aminoglycosides Causes misreading of the
code on the mRNA template
to inhibit protein synthesis
16. Which statement is accurate regarding the Gentamicin continues to ex-
antibacterial action of gentamicin ert antibacterial effects even
after plasma level decrease
below detectable levels
17. If a patient was treated with the macrolide Temporarily stop simvastatin
erythromycin, he/she should while taking erythromycin
18. 24 year old woman returned from vacation Ciprofloxacin
abroad suffering from traveler's diarrhea,
and her problem has not responded to an-
tidiarrheal drugs. A pathogenic gram-neg-
ative bacillus is suspected. Which drug is
most likely to be effective in the treatment
of this patient
19. Which is accurate about fluoroquinolones Fluoroquinolones have dif-
ferent therapeutic applica-
tions depending on the gen-
eration
20. Which adverse effect is MOST LIKELY to
occur with sulfonamides 21. Which is true about
ciprofloxacin
dosing information in their drug labeling dence-based literature on
the safe and effective use of
medications in children
2. Why are neonates at greater risk for toxicity Protein binding is decreased
with highly protein-bound drugs in neonates increasing the
amount of free drug avail-
able
3. At what age are adult levels of renal function 12 months
achieved
4. What is the most accurate device for mea- An oral syringe
suring a 2.5mL dose for a child
5. How do you help prevent medication errors Write out the term daily
6. In pediatric patients gastric acidity does not 2 years
reach adult values for
7. Nalidixic acid may cause in chil- cartilage erosion
dren
8. Altered absorption of drugs in the elderly Delayed
may result in drug response
9. You have an elderly patient taking war- You will need to decrease
farin. You add another protein binding drug. dose of warfarin
Which of the following statements is cor-
rect?
10. In elderly, proper index of renal function is Glomerular filtration rate
(GFR)
11. List that identifies drugs with high likeli- of the penicillin's
hood of cause adverse effects in elderly involve inhibition of
12. Primary mechanism of antibacterial action
,Beers list
, Cell wall synthesis by bind-
ing and inactivating penicillin
binding proteins (PBPs)
13. Which statement about vancomycin is accu- Increases bacterial cell wall
rate permeability and inhibits
RNA synthesis
14. The mechanism of action of the tetracy- Inhibiting protein synthesis
clines involves
15. Mechanism of action of aminoglycosides Causes misreading of the
code on the mRNA template
to inhibit protein synthesis
16. Which statement is accurate regarding the Gentamicin continues to ex-
antibacterial action of gentamicin ert antibacterial effects even
after plasma level decrease
below detectable levels
17. If a patient was treated with the macrolide Temporarily stop simvastatin
erythromycin, he/she should while taking erythromycin
18. 24 year old woman returned from vacation Ciprofloxacin
abroad suffering from traveler's diarrhea,
and her problem has not responded to an-
tidiarrheal drugs. A pathogenic gram-neg-
ative bacillus is suspected. Which drug is
most likely to be effective in the treatment
of this patient
19. Which is accurate about fluoroquinolones Fluoroquinolones have dif-
ferent therapeutic applica-
tions depending on the gen-
eration
20. Which adverse effect is MOST LIKELY to
occur with sulfonamides 21. Which is true about
ciprofloxacin
