ACOG PB139 Premature Rupture of Membranes
Questions With Complete Solutions 2025
How common is preterm deliver in the USA? - (answers)12% of all births
How common is PROM? - (answers)3%
What is the main issue with management of PROM? - (answers)Prematurity vs Risk of
Expectant Management (Infection, Abruption, Umbilical cord accident)
Definition of PROM - (answers)Rupture of membranes before the onset of labor
Definition of PPROM - (answers)Membrane rupture before labor and before 37 weeks of
gestation
What causes rupture of membranes? - (answers)Normal weakening of membranes, shearing
forces from uterine contractions.
Risk factors for PROM? - (answers)Intraamniotic infection, hx of PROM, Shortened cervix,
2nd/3rd trimester bleed, low BMI, low SES, Cigarette smoking, illicit drug use
How often is PROM in term pregnancies? - (answers)8%. Generally followed by onset of labor.
Consequence of term PROM? - (answers)Intrauterine infection, increases with duration of
membrane rupture
How many patients deliver regardless of obstetric managment of PPROM? How many between
2-5 weeks? - (answers)50%, 70-80%
, 2
Latency after membrane rupture is _____ correlated with GA at time of PPROM. -
(answers)Inversely
Clinically evident intraamniotic infection occurs in ____. Post partum infection occurs in _____.
Incidence of infection is higher at _______. - (answers)15-25%
15-20%
Earlier GA
Placental abruption occurs in ____ of PPROM. - (answers)2-5%
Most common issues/risks of prematurity? - (answers)Respiratory distress - most common
Sepsis
Intraventricular hemorrhage
Necrotizing Enterocolitis
PPROM w/ intrauterine inflammation has increased risk of what comorbidity? -
(answers)Neurodevelopmental impairment. Early GA associated with increased risk of neonatal
white matter damage.
How often does PROM occur prior to viability? - (answers)1%
Maternal complications from previable PROM? - (answers)Intraamniotic infection,
endometritis, abruptio placentae, retained placenta. Sepsis occurs 1% of time.
How common is pulmonary hypoplasia after PROM before 24 weeks? - (answers)10-20%.
Rarely lethal with PROM subsequent to 23-24 weeks.