Drugs can affect - Answers The communication between neurons involves the release of
neurotransmitters, which bind with receptors and either excite or inhibit the activity of the postsynaptic
cell.
Drugs can affect it in many ways:
They can stimulate or inhibit the release of neurotransmitters, mimic the effects of neurotransmitters on
postsynaptic receptors, block these effects, or interfere with the reputable of a neurotransmitter once it
is released.
A drug can alter - Answers the perceptions, thoughts, and behaviours controlled by particular
neurotransmitters
Effects of drugs on synaptic transmission - Answers Stimulating or inhibiting the release of
neurotransmitters.
Stimulating or blocking postsynaptic receptors.
Inhibiting reuptake.
In the brain, most synaptic communication is accomplished by two neurotransmitters - Answers
Glutamate: has excitatory effects.
GABA: has inhibitory effects.
Glutamate - Answers The most important excitatory neurotransmitter in the brain and spinal cord.
GABA - Answers The most important inhibitory neurotransmitter in the brain.
Barbiturate - Answers A drug that causes sedation; one of several derivatives of barbituric acid.
Antianxiety drug - Answers A tranquilizer, which reduces anxiety.
Benzodiazepine - Answers A class of drug having anxiolytic (tranquilizing) effects, such as diazepam
(Valium).
Acetylcholine (ACh) - Answers A neurotransmitter found in the brain, spinal cord, and parts of the
peripheral nervous system; responsible for muscular contraction.
It is the primary neurotransmitter secreted by the axons of motor neurons.
All muscular movement is accomplished by the release of acetylcholine.
Two drugs that affect the release of acetylcholine - Answers botulinum toxin
the venom of the black widow spider
, Botulinum toxin - Answers A drug that prevents the release of acetylcholine by terminal buttons
Black widow spider venom - Answers A drug that stimulates the release of acetylcholine by terminal
buttons.
The enzyme acetylcholinesterase (AChE) - Answers Can deactivate ACh
But it can be inactivated by various drugs, such as neogstigmine.
Neostigmine - Answers A drug that enhances the effects of acetylcholine by blocking the enzyme that
destroys it.
Nicotine - Answers A drug that binds with and stimulates acetylcholine receptors, mimicking the effects
of this neurotransmitter
Curare - Answers A drug that binds with and blocks acetylcholine receptors, preventing the
neurotransmitter from exerting its effects.
Monamine - Answers A category of neurotransmitters that includes
dopamine
norepinephrine
serotonin
Dopamine (DA) - Answers A monoamine neurotransmitter involved in control of brain mechanisms of
movement and reinforcement.
It has been implicated in several important functions, including movement, attention, learning, and the
reinforcing effects of drugs that tend to abuse.
Parkinson's disease - Answers A neurological disorder characterized by tremors, rigidity of the limbs,
poor balance, and difficulty in initiating movements; caused by generation of a system of dopamine-
secreting neurons.
Norepinephrine (NE) - Answers A monoamine neurotransmitter involved in alertness and vigilance and
control of REM sleep
Serotonin - Answers A monoamine neurotransmitter involved in the regulation of mood;
In the control of eating, sleep, and arousal; and in the regulation of pain.
Several hallucinogenic drugs appear to produce their effects by interacting with serotonergic
transmission. - Answers For example, LSD (lysergic acid diethylamide)
LSD - Answers Lysergic acid diethylamide; a hallucinogenic drug that blocks a category of serotonin
receptors.