1. Immunology- Block 1 Exam
Questions With Answers
2. Pattern Associated Molecular Patterns (PAMPs)
3. molecules shared by groups of related microbes that
are essential for the survival of those organisms
4. Ligand
5. any molecule or atom which binds reversibly to a
protein
6. Epitope
7. smallest molecular structure recognized by a specific
receptor
8. Dendritic Cells, Macrophages, B Cells
9. What are the professional APCs?
10. Peripheral Tolerance of T Cells
11. Auto reactive lymphocytes are kept anergic -
nonreactive
12. regulatory immune cells in circulation
13. Fetomaternal Tolerance
14. prevents maternal immune system response
from attacking developing fetus, esp regarding diff
blood types
15. Antigen
16. material that can evoke an immune response;
collection of sometimes repeating and/or unique
epitopes.
, IMMUNO
17. Tolerance
18. The prevention of an immune response against
a particular antigen; responses to future exposure
can be diminished
19. Immune System
20. A complex network of cells, tissues, organs, and
the substances they make that helps the body fight
infections and other diseases.
21. On professional APCs
22. MHC I and MHC II are both found where
23. Pathogen
24. disease causing or harmful organisms
25. Peripheral Tolerance
26. ensures that self reactive T and B cells which
escaped central tolerance do not cause autoimmune
disease
27. thymus and bone marrow
28. Where does central tolerance occur?
29. Positive and Negative Selection
30. For tolerance, what process does T cells
undergo
31. Clonal deletion or receptor editing
32. For tolerance, what process does B cells
undergo
, IMMUNO
33. Peripheral tissues and lymph nodes
34. Where does peripheral tolerance occur
35. Inflammation
36. response to tissue damage; can be chronic or
acute
37. all nucleated cells
38. where are MHC Class I genes found
39. Pattern Recognition Receptors (PRRs)
40. proteins capable of recognizing molecules
frequently found in pathogens
41. Positive Selection
42. T-cells in the thymus that moderately bind MHC
complexes receive survival signals - intermediate
affinity
43. Immunoglobulin
44. diverse group of globular molecules found in
blood and tissues; usually bound B cells and plasma
cells
45. Negative Selection
46. T cells whose TCRs bind too strongly to MHC
complexes and will likely be self reactive - too high
affinity
47. Central Tolerance
48. removes self-reactive lymphocytes in an early
stage of development via apoptosis
49. on antigen presenting cells APCs
, IMMUNO
50. where are MHC Class II genes found
51. Immunological memory
52. once an infectious organism stimulates an
adaptive response subsequent encounters with that
organism produce mild or even unapparent effects
because of therapia and enhanced action of
antibodies or effector T cells
53. Antibody
54. immunoglobin that specifically binds to known
ligand and or epitope - usually used in terms of
circulating Ig
55. Autoreactivity - self attacking self- which leads
to autoimmune disease
56. Consequences of self recognition failure
57. Auto reactive lymphocytes can attack the self
and damage host tissues
58. What happens when the body cannot distinguish
self
59. Education, Prevention, and Treatment
60. What are the three forms of health intervention
61. Research and Study
62. What is the Health Prevention of Education
63. Avert occurrence of illness
64. What is the Health Prevention of Prevention
65. Decrease discomfort and increase health
66. What is the Health Prevention of Treatment