Bioreactor Design for Tissue Engineering Exam With
Complete Solutions
Scalable in vitro culture - ANSWER Important for toxicology studies and tissue
comparison.
Bioreactor advantages - ANSWER Controlled environment for reproducible data and
automation.
Scalability in design - ANSWER Consider from the beginning for optimized flow patterns.
Bioreactor design knowledge - ANSWER Requires understanding of cells and their
environment.
Optimal bioreactor design - ANSWER Combines experimental, CFD, and mathematical
modeling.
In vivo - ANSWER Processes occurring within a living organism.
In vitro - ANSWER Processes occurring outside a living organism.
Mass transfer in culture flasks - ANSWER Stiff surface with diffusion limited by
concentration gradient.
Mass transfer in porous scaffold - ANSWER Convective flow in bulk, diffusion in pores.
Key parameters for scale up - ANSWER Velocity, forces, and concentration gradients.
Complete Solutions
Scalable in vitro culture - ANSWER Important for toxicology studies and tissue
comparison.
Bioreactor advantages - ANSWER Controlled environment for reproducible data and
automation.
Scalability in design - ANSWER Consider from the beginning for optimized flow patterns.
Bioreactor design knowledge - ANSWER Requires understanding of cells and their
environment.
Optimal bioreactor design - ANSWER Combines experimental, CFD, and mathematical
modeling.
In vivo - ANSWER Processes occurring within a living organism.
In vitro - ANSWER Processes occurring outside a living organism.
Mass transfer in culture flasks - ANSWER Stiff surface with diffusion limited by
concentration gradient.
Mass transfer in porous scaffold - ANSWER Convective flow in bulk, diffusion in pores.
Key parameters for scale up - ANSWER Velocity, forces, and concentration gradients.
