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Where does breast tissue normally develop? - ✔✔Along the breast line
- located from under the arms down to the groin
What are the 3 stages of early breast development? - ✔✔1. In utero
2. First 2 months of life
3. Puberty
Breast development during menstruation - ✔✔- Estrogen: Induces
Ductal System development
- Progesterone: Induces Lobular-Alveolar development
What is Lactogenesis? - ✔✔The initiation of milk production
How many stages of Lactogensis are there? - ✔✔4
What stages of Lactogenesis occur during pregnancy? - ✔✔1 and 2
Lactogenesis 1 - ✔✔Ductal and Lobular-Alveolar systems grow at an
accelerated rate (influenced by hormones)
,- breasts enlarge
- high progesterone levels cause an increase in alveoli
- colostrum begins to produce in the alveoli
When does Lactogenesis 1 occur? - ✔✔around 16 weeks
Lactogenesis 2 - ✔✔The placenta is released from the uterus and
progesterone levels drop
- this causes the alveolar cells to begin to release milk and allows them to
continue to produce more milk
How long does Lactogenesis 2 last? - ✔✔2-4 days
What are the 5 main areas of the breast? - ✔✔- Upper Inner
- Lower Inner
- Upper Outer
- Lower Outer
- Tail of Spence
What are the 2 types of breast tissue and what are they composed of? -
✔✔- Parenchyma: ductal and lobular-alveolar structures
- Strom: connective tissue (fat, vascular, nerve, lymphatic)
What is an Alveolus - ✔✔Small cavity where milk is produced and stored
- made of epithelial cells
, What are Alveoli? - ✔✔multiple alveolus
What is the Intra-lobular duct? - ✔✔Connects a lobule to the lactiferous
ducts
What is a Mammary Lobule? - ✔✔10-100 alveoli combined together
What are Lactiferous Ducts? - ✔✔connects mammary lobules/intra-
lobular ducts to the nipple
Breast Anatomy - ✔✔
What surrounds the breast tissue? - ✔✔Fat
Nerves
Lymph Tissue
Vascular Network
Myoepithelial Cells
What is the purpose of the Myoepithelial cells? - ✔✔They surround the
alveolus and contract (like a muscle)
- pushes milk out into the ducts
What is the purpose of the Vascular Network surrounding breast tissue? -
✔✔- supplies nutrients, materials, hormones to each alveolus for milk
production
- supplies hormones to the myoepithelial cells for ejection of milk