PATHOPHYSIOLOGY 9THEDITION
MCCANCE TESTBANK COMPLETE| ALL
CHAPTERS
,Table of Contents
UNIT I The Cell
Cellular Biology
Altered Cellular and Tissue Biology: Environmental Agents
The Cellular Environment: Fluids and Electrolytes, Acids and Bases
UNIT II Genes and Gene-Environment Interaction
Genes and Genetic Diseases
Genes, Environment-Lifestyle, and Common Diseases6 Epigenetics and Disease
UNIT III Mechanisms of Self-Defense
7 Innate Immunity: Inflammation and Wound Healing8 Adaptive Immunity
9 Alterations in Immunity10 Infection
Stress and Disease
UNIT IV Cellular Proliferation: Cancer
Cancer Biology
Cancer Epidemiology
Cancer in Children and Adolescents
UNIT V The Neurologic System
Structure and Function of the Neurologic System
Pain, Temperature Regulation, Sleep, and Sensory Function
17Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function18 Alterations of the Brain, Spinal Cord, and
Peripheral Nerves
Neurobiology of Schizophrenia, Mood Disorders, Anxiety Disorders, Posttraumatic StressDisorder, and obsessive-
compulsive disorder
Alterations of Neurologic Function in Children
UNIT VI The Endocrine System
Mechanisms of Hormonal Regulation22 Alterations of Hormonal Regulation
Obesity, Starvation, and Anorexia of Aging
UNIT VII The Reproductive Systems
Structure and Function of the Reproductive Systems25 Alterations of the Female Reproductive System
26 Alterations of the Male Reproductive System27 Sexually Transmitted Infections
UNIT VIII The Hematologic System
28 Structure and Function of the Hematologic System29 Alterations of Hematologic Function
Alterations of Hematologic Function in Children
UNIT IX The Cardiovascular and Lymphatic Systems
Structure and Function of the Cardiovascular and Lymphatic Systems32 Alterations of Cardiovascular Function
Alterations of Cardiovascular Function in Children
,UNIT X The Pulmonary System
Structure and Function of the Pulmonary System35 Alterations of Pulmonary Function
Alterations of Pulmonary Function in Children
UNIT XI The Renal and Urologic Systems
Structure and Function of the Renal and Urologic Systems38 Alterations of Renal and Urinary Tract Function
Alterations of Renal and Urinary Tract Function in Children
UNIT XII The Digestive System
Structure and Function of the Digestive System, 128541 Alterations of Digestive Function
Alterations of Digestive Function in Children
UNIT XIII The Musculoskeletal System
Structure and Function of the Musculoskeletal System44 Alterations of Musculoskeletal Function
Alterations of Musculoskeletal Function in Children
UNIT XIV The Integumentary System
Structure, Function, and Disorders of the Integument47 Alterations of the Integument in Children
UNIT XV Multiple Interacting Systems
48 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults 49 Shock, Multiple Organ Dysfunction Syndrome, and
Burns in Children
, Chapter 1: Cellular Biology
MULTIPLE CHOICE
Which statement best describes the cellular function of metabolic absorption?
Cells can produce proteins. c. Cells can take in and use nutrients.
Cells can secrete digestive enzymes. d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances from theirsurroundings. The remaining options
are not inclusive in their descriptions of cellular metabolic absorption.
PTS: 1 REF: Page 2
Most of a cell’s genetic information, including RNA and DNA, is contained in the:
Mitochondria c. Nucleolus
Ribosome d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the cellular DNA, and the DNA-
binding proteins, such as the histones, which regulate its activity. The other options do not contain most of a cell’s genetic
information.
PTS: 1 REF: Page 2
Which component of the cell prodNuUceRsSIhNyGdTroBg.CeO
nMperoxide (H2O2) by using oxygen to remove hydrogen atoms from
specific substrates in an oxidative reaction?
Lysosomes c. Ribosomes
Peroxisomes d. Oxyhydrosomes
ANS: B
Peroxisomes are so named because they usually contain enzymes that use oxygen to remove hydrogen atoms from specific
substrates in an oxidative reaction that produces H2O2, which is a powerful oxidant and potentially destructive if it accumulates
or escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized in the nucleolus and
secreted into the cytoplasm through pores in the nuclear envelope called nuclear pore complexes. Lysosomes are saclike
structures that originate from the Golgi complex and contain more than 40 digestive enzymes called hydrolases, which catalyze
bonds in proteins, lipids, nucleic acids, and carbohydrates. Oxyhydrosomesare involved in enzyme production.
PTS: 1 REF: Page 8
Which cell component is capable of cellular autodigestion when it is released during cellinjury?
Ribosome c. Smooth endoplasmic reticulum
Golgi complex d. Lysosomes
ANS: D
MCCANCE TESTBANK COMPLETE| ALL
CHAPTERS
,Table of Contents
UNIT I The Cell
Cellular Biology
Altered Cellular and Tissue Biology: Environmental Agents
The Cellular Environment: Fluids and Electrolytes, Acids and Bases
UNIT II Genes and Gene-Environment Interaction
Genes and Genetic Diseases
Genes, Environment-Lifestyle, and Common Diseases6 Epigenetics and Disease
UNIT III Mechanisms of Self-Defense
7 Innate Immunity: Inflammation and Wound Healing8 Adaptive Immunity
9 Alterations in Immunity10 Infection
Stress and Disease
UNIT IV Cellular Proliferation: Cancer
Cancer Biology
Cancer Epidemiology
Cancer in Children and Adolescents
UNIT V The Neurologic System
Structure and Function of the Neurologic System
Pain, Temperature Regulation, Sleep, and Sensory Function
17Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function18 Alterations of the Brain, Spinal Cord, and
Peripheral Nerves
Neurobiology of Schizophrenia, Mood Disorders, Anxiety Disorders, Posttraumatic StressDisorder, and obsessive-
compulsive disorder
Alterations of Neurologic Function in Children
UNIT VI The Endocrine System
Mechanisms of Hormonal Regulation22 Alterations of Hormonal Regulation
Obesity, Starvation, and Anorexia of Aging
UNIT VII The Reproductive Systems
Structure and Function of the Reproductive Systems25 Alterations of the Female Reproductive System
26 Alterations of the Male Reproductive System27 Sexually Transmitted Infections
UNIT VIII The Hematologic System
28 Structure and Function of the Hematologic System29 Alterations of Hematologic Function
Alterations of Hematologic Function in Children
UNIT IX The Cardiovascular and Lymphatic Systems
Structure and Function of the Cardiovascular and Lymphatic Systems32 Alterations of Cardiovascular Function
Alterations of Cardiovascular Function in Children
,UNIT X The Pulmonary System
Structure and Function of the Pulmonary System35 Alterations of Pulmonary Function
Alterations of Pulmonary Function in Children
UNIT XI The Renal and Urologic Systems
Structure and Function of the Renal and Urologic Systems38 Alterations of Renal and Urinary Tract Function
Alterations of Renal and Urinary Tract Function in Children
UNIT XII The Digestive System
Structure and Function of the Digestive System, 128541 Alterations of Digestive Function
Alterations of Digestive Function in Children
UNIT XIII The Musculoskeletal System
Structure and Function of the Musculoskeletal System44 Alterations of Musculoskeletal Function
Alterations of Musculoskeletal Function in Children
UNIT XIV The Integumentary System
Structure, Function, and Disorders of the Integument47 Alterations of the Integument in Children
UNIT XV Multiple Interacting Systems
48 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults 49 Shock, Multiple Organ Dysfunction Syndrome, and
Burns in Children
, Chapter 1: Cellular Biology
MULTIPLE CHOICE
Which statement best describes the cellular function of metabolic absorption?
Cells can produce proteins. c. Cells can take in and use nutrients.
Cells can secrete digestive enzymes. d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances from theirsurroundings. The remaining options
are not inclusive in their descriptions of cellular metabolic absorption.
PTS: 1 REF: Page 2
Most of a cell’s genetic information, including RNA and DNA, is contained in the:
Mitochondria c. Nucleolus
Ribosome d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the cellular DNA, and the DNA-
binding proteins, such as the histones, which regulate its activity. The other options do not contain most of a cell’s genetic
information.
PTS: 1 REF: Page 2
Which component of the cell prodNuUceRsSIhNyGdTroBg.CeO
nMperoxide (H2O2) by using oxygen to remove hydrogen atoms from
specific substrates in an oxidative reaction?
Lysosomes c. Ribosomes
Peroxisomes d. Oxyhydrosomes
ANS: B
Peroxisomes are so named because they usually contain enzymes that use oxygen to remove hydrogen atoms from specific
substrates in an oxidative reaction that produces H2O2, which is a powerful oxidant and potentially destructive if it accumulates
or escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized in the nucleolus and
secreted into the cytoplasm through pores in the nuclear envelope called nuclear pore complexes. Lysosomes are saclike
structures that originate from the Golgi complex and contain more than 40 digestive enzymes called hydrolases, which catalyze
bonds in proteins, lipids, nucleic acids, and carbohydrates. Oxyhydrosomesare involved in enzyme production.
PTS: 1 REF: Page 8
Which cell component is capable of cellular autodigestion when it is released during cellinjury?
Ribosome c. Smooth endoplasmic reticulum
Golgi complex d. Lysosomes
ANS: D
