Pharmacokinetics
study of drug movement throughout the body through for basis process
- absorption
-distribution
- metabolism
- excretion
Absorption
movement of drug from it site of administration to blood.
factors affecting absorption
rate of dissolution, surface area, blood flow, lipid solubility, pH partitioning, routes of
administration
Is Barbituates an inducer or an inhibitor
inducer
St. Johns wort an inducer or inhibitor
inducer
Careamazepine inducer or inhibitor
inducer
Rifampin inducer or inhibitor
inducer
alcohol inducer or inhibitor
inducer
Phenytoin inducer or inhbitor
inducer
Griseofulvin inducer or inhibitor
inducer
, Phenobarbital inducer or inhibitor
inducer
Sulfonyureas inducer or inhibitor
inducer
Valproate inducer or inhibitor
inhibitor
Isoniazid inducer or inhibitor
inhibitor
Sulfonamindes inducer or inhibitor
inhibitor
Amiodarone inducer or inhibitor
inhibitor
Chloramphenicol inducer or inhibitor
inhibitor
Ketoconazole inducer or inhibitor
inhibitor
Grapefruit juice inducer or inhibitor
inhibitor
Quinadine inducer or inhibitor
inhibitor
Examples of pure opioid agonists
Morphine, Codeine, Meperidine
What is used to calculate patients overdose risk
Calculated MME