NAPLEX Infectious Disease Practice Questions with Answers

Empiric treatment for Meningitis for newborn to 1 monthampicillin plus either cefotaxime or an AG empiric treatment for meningitis for 1 month old to 50 year oldvanco + ceftriaxone or cefotaxime empiric treatment for meningitis 50 y/o or oldervanco + ampicillin + ceftriaxone or cefotaxime what is bacterial organism that causes meningitis is not treated with single therapy of ceftriaxone, cefotaxime, ampicillin or pen G (i.e. none of those drugs are rec'd trx))?strep pneumoniae Which two organisms that cause meningitis have a recommended treatment with ampicillin or pen G?listeria monocytogenes and streptococcus agalactiae what is the recommended therapy for meningitis caused by neisseria meningitidis, H. influenza, or E. coli?ceftriaxone or cefotaxime what is the preferred treatment for MRSA meningitis?vancomycin with possible add of rifampin (consider 25-30 mg/kg LD of vanc). alternative can use linezolid or TMP-SMX what is the empiric initial treatment for endocarditis?vancomycin, to cover MRSA unless the MIC of s. aureus is > 2mg/dL -> use daptomycin is Linezolid a good choice for catheter-related infections?no, only as secondary trx for VRE catheter infections name some reasons a pt should get empiric coverage of CAnddia for endocarditis?femoral catheter, TPN use, prolonged abx use, hematologic malignancy, transplant, or colonization of candida how long should treatment of uncomplicated catheter related infections last?coag-neg staph is 5-7 days, but all others are 7-14 day therapy courses ANC equationANC= (%bands + % segs) x WBC what ANC defines neutropenia?< 500 cells/mL, fever may be the only symptom diagnostic criteria for febrile neutropeniaANC < 500 with either a single temp >/= 38.3C (100.9F), or temp >/= 38C (100.4) for over 1 hour. initial treatment for low risk febrile neutropeniaoral cipro + amox-clav