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Pathophysiology Inflammation UPDATED Exam Questions and CORRECT Answers

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Human defense mechanisms work to? - protect from injury and infection What is the first line of defense - physical and mechanical barriers-epithelial cells tightly associated in: skin, mucous membrane, lining of the respiratory tract, GI tract, low temperature on body surface. Biochemical barriers are where on the body? - the skin. The skin does what as a biochemical barrier? - produces lactic acid in sebaceous glands. And perspires, it contains lysosomes that attack cell walls (+) gram bacteria. Epithelial-Derived chemicals are called? - Antibacterial peptides. What are the 2 classes of antibacterial peptides secreted by 2 epithelial cells? - 1. Cathelicidins 2. Defensins --These both poke holes in bacterial membrane

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