HMX Immunology Practice Questions with 100% Correct Answers | Latest Version 2024 | Verified

Which cells are tissue resident sentinel cells - mast cell, macrophage, dendritic cell Which 2 cells are circulating blood cells that will enter tissue in response to inflammation? - Neutrophils, Monocytes Mast cell - Cells that release chemicals (such as histamine) that promote inflammation. Neutrophil - Most abundant leukocyte, increase due to bacterial infection, burns, and stress. Phagocyte that rapidly dies after ingesting microbe. Macrophages - Phagocyte that cleans up apoptotic cells. When a monocyte moves into the tissues, it changes rapidly and becomes a _____________ - macrophage Leukocyte adhesion deficiency (LAD) is a genetic defect that leads to recurrent infections in the tissue and severe problems with wound healing. LAD patients also develop severe gingivitis (infections and inflammation of the gums). In LAD, leukocyte migration into tissues is severely impaired. All of these problems can be traced back to a genetic defect. Of the genetic defects listed below, which is the most likely cause of LAD? - A mutation that introduces a stop codon into a gene that encodes part of the LFA-1 molecule (leading to a truncated protein).