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Lecture notes

Class notes Neuronal Communication 5.3.6

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Synapses 2 5.3.6

Synapses and nervous communication

Nerve junctions can involve several neurones

Excitatory post-synaptic potential
Only a few vesicles fuse w/ pre-synaptic membrane
A small number of acetylcholine molecules diffuse across synaptic cleft
Small depolarisation and action potential isn’t produced

Combination of several EPSPs to reach threshold value to cause an action potential – summation

Temporal summation – several action potentials in same pre-synaptic neurone
Spatial summation – action potentials arriving from several different pre-synaptic neurones




Inhibitory post-synaptic potentials
Reduces effect of summation and prevents an action potentials in post-synaptic neurone

Control of communication

 Spatial summation creates specific responses e.g several different stimuli warn us of danger
 Several ESPSs can be prevented Form creating an A.P by one IPSP
 Synapses ensure A.P travel in one direction
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