King’s College London
4BBY1060 Fundamentals of Physiology & Anatomy
Sample Midsessional Paper
Section 1. Attempt ALL questions. Choose the SINGLE best answer. Negative
marking would not be employed in this section. Correct answers earn 1 mark
and incorrect answers earn 0 mark. Total [20 marks]
Section 2. Attempt ALL questions. Select True or False for each of the four
twigs for each question. Negative marking would be employed in this section: a
correct answer for each twig (A, B, C or D) earns +0.5 marks; each incorrect
twig earns -0.25 marks; twigs left blank earn 0 marks. Total [20 marks].
Under exam conditions, we would recommend spending a minimum of 30min
on EACH of the two sections.
There is another version of this paper with answers. You
are advised to have a go at completing the test in 1 hr
before looking at the answers.
, Homeostasis
1. The dilation of skin blood vessels in response to raised core temperature
is an example of what type of homeostatic control mechanism?
A. Negative feedback.
B. Flow auto-regulation.
C. Reactive hyperemia.
D. Positive feedback.
E. Feed-forward.
2. Without feedback control, which physiological variables would be
affected by an increased whole body metabolic rate?
A. Tissue blood flow.
B. Minute ventilation and cardiac output.
C. Tissue PO2 alone.
D. Tissue PO2 and tissue PCO2.
E. Tissue PCO2 alone.
Muscle cells
3. Which statement best describes the ‘all or nothing’ nature of contraction
in skeletal muscle?
A. Either all fibers in a muscle contract at once or none of them do.
B. Each fiber will always contract fully if stimulated by a motor nerve.
C. The muscle isn’t capable of sustained contractions.
D. All motor units need to be stimulated for a muscle to contract.
E. Action potential frequency is fixed.
4. Which statement best describes how smooth muscle differs from both
skeletal and cardiac muscle?
A. It requires Ca2+ to bind to myosin light-chain kinase for contraction to
occur.
B. It requires direct coupling between voltage sensor and Ca 2+ release
channel for contraction to occur.
C. It does not require K+ channels for action potential repolarization to
occur.
D. It does not require an increase in intracellular Ca2+ for contraction to
occur.
E. It requires phosphorylation of troponin C for contraction to occur.
4BBY1060 Fundamentals of Physiology & Anatomy
Sample Midsessional Paper
Section 1. Attempt ALL questions. Choose the SINGLE best answer. Negative
marking would not be employed in this section. Correct answers earn 1 mark
and incorrect answers earn 0 mark. Total [20 marks]
Section 2. Attempt ALL questions. Select True or False for each of the four
twigs for each question. Negative marking would be employed in this section: a
correct answer for each twig (A, B, C or D) earns +0.5 marks; each incorrect
twig earns -0.25 marks; twigs left blank earn 0 marks. Total [20 marks].
Under exam conditions, we would recommend spending a minimum of 30min
on EACH of the two sections.
There is another version of this paper with answers. You
are advised to have a go at completing the test in 1 hr
before looking at the answers.
, Homeostasis
1. The dilation of skin blood vessels in response to raised core temperature
is an example of what type of homeostatic control mechanism?
A. Negative feedback.
B. Flow auto-regulation.
C. Reactive hyperemia.
D. Positive feedback.
E. Feed-forward.
2. Without feedback control, which physiological variables would be
affected by an increased whole body metabolic rate?
A. Tissue blood flow.
B. Minute ventilation and cardiac output.
C. Tissue PO2 alone.
D. Tissue PO2 and tissue PCO2.
E. Tissue PCO2 alone.
Muscle cells
3. Which statement best describes the ‘all or nothing’ nature of contraction
in skeletal muscle?
A. Either all fibers in a muscle contract at once or none of them do.
B. Each fiber will always contract fully if stimulated by a motor nerve.
C. The muscle isn’t capable of sustained contractions.
D. All motor units need to be stimulated for a muscle to contract.
E. Action potential frequency is fixed.
4. Which statement best describes how smooth muscle differs from both
skeletal and cardiac muscle?
A. It requires Ca2+ to bind to myosin light-chain kinase for contraction to
occur.
B. It requires direct coupling between voltage sensor and Ca 2+ release
channel for contraction to occur.
C. It does not require K+ channels for action potential repolarization to
occur.
D. It does not require an increase in intracellular Ca2+ for contraction to
occur.
E. It requires phosphorylation of troponin C for contraction to occur.
