NR 293 (Pharm) Final Exam Questions With Verified Answers 2023/2024 (Graded A+)

NR 293 (Pharm) Final Exam Questions With Verified Answers 2023/2024 (Graded A+). patient education/ nursing interventions for sulfonamides - answerPt. Education: take with a full glass of water increase fluid intake report sore throat, bruising, bleeding avoid direct sunlight Nursing interventions: push fluids Monitor CBC signs of bleeding (liver damage) check for superinfection beta lactam penicilins MOA - answersafest class bacteriocidal inhibition of bacterial cell wall synthesis uses of penicillins - answerstrep staph pneumonia meningitis skin, bone, and joint infections stomach infections blood and valve infections gas gangrene tetanus anthrax sickle cell anemia in infants broad spectrum penicillin - answerbacteriocidal ecoli salmonella influenza adverse effects of penicillin - answerallergy most common rash pruritus fever anaphylaxis lowered WBC, RBC, platelet count GI upset patient education for penicillins - answerside effects bleeding increase fluid intake take with food drugs for penicillin - answerbroad spectrum: amoxicillin combination: piperacillin plus tazobactam (zosyn) give 3 times a day infused over 4 hours or every 6 hours infused over 1 hour cephalosporins MOA - answerlargest class interfere with bacterial cell wall synthesis, bind to the same penicillin binding proteins uses of cephalosporins - answertreatment of gram positive and negative anaerobic bacteria mostly gram negative patients who cannot tolerate the less expensive penicillins respiratory infections urinary infections skin infections bone and joint infections genital infections contraindications of cephalosporins - answermay cause cross allergy potential with penicillin adverse effects of cephalosporins - answerweakness pruritus GI distress high doses can cause bleeding seizures nephrotoxicity patient education of cephalosporins - answerside effects administration monitor kidney function with 1st generation drugs for cephalosporins - answerfirst generation Cefazolin (ancef) not effective for beta lactase gram positive bacteria may cause kidney toxicity macrolides MOA - answerbroad spectrum inhibit protein synthesis binds reversibly to 50S ribosomal subunits of microbes uses of macrolides - answerwhooping cough legionnaires disease Hpylori streptococcus influenza mycoplasma pneumonia generic use: respiratory GI tract skin soft tissue adverse effects of macrolides - answertinnitus ototoxicity mild GI distress diarrhea abdominal pain superinfectionm hepatotoxicity patient education/ nursing interventions - answerPatient education: finish full regimen monitor hepatic function food-drug interactions (fruit juices) take on empty stomach Nursing interventions: monitor hepatic function bleeding, bruising, dark tea looking urine, jaundice drugs for macrolides - answerwe do not need peak or troughs for Azithromycin (Zithromax, Zpack) only take for 5 days due to its long half life administer antacids 2 hours before or after on an empty stomach with full glass of water tetracyclines MOA - answerbroad spectrum inhibit protein synthesis uses of tetracyclines - answeracne Rocky Mountain spotted fever typhus cholera lymes disease peptic ulcers Hpylori contraindications of tetracyclines - answerdrug allergy children under 8 pregnancy category D, fetal growth/develeopment milk antacids iron decrease effect of oral contraceptives increases effect of digoxin adverse effects of tetracycline - answerdiscoloration of teeth retard fetal skeletal development if taken during pregnancy photsensitivity alteration of intestinal and vaginal flora reversible bulging fontanelles in neonates thrombocytopenia heolytic anemia hepatotoxicity (IV or high doses) nephrotoxicity (outdated meds) GI distress patient education of tetracyclines - answeruse sunblock store out of light/heat good oral hygeine food-drug interactions labs administration times drugs for tetracyclines - answertetracycline (achromycin) administer 1-2 hours after meals aminoglycosides MOA - answerprevent protein synthesis in bacteria uses of aminoglycosides - answerserious gram negative bacteria: ecoli serratia proteus psuedomonas mycobacteria some protozoans common category to treat klebsiella combined with penicillin, cephalosporins, or vancomycin for enterococcal infections may be given to sterilize bowel prior to surgery contraindications for aminoglycosides - answerrenal patients adverse effects of aminoglycosides - answernephrotoxicity