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Lecture 1 notes hand written

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This is a detailed in class notes of the first lecture for this module which includes figures and diagrams.

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131056008 based Medicine and
21 Evidence
Diagnostics
-
-




"
Evidence based medicine is the conscientious ,
explicit ,
and


evidence
judicious use of current best in
making decisions

"
about the care of individual patients .




> The randomised
strongest evidence comes from meta -


analysis ,



controlled clinical trials and systematic reviews .




> EBM evolved evidence based medical :
has also into -


practice

developing guidelines and policies for groups of patients or




populations .




Coursework -
two pieces 50% total
,


> Week 5 : Online MCQ on
epidemiology ( 20% )

> Week 8 :
drug information leaflet for Dr and patient (30%)




coursework 2




* Does to inc side effects
not require
.

,The exam ( 50%3

, L1 History and Rationale




History of evidence -
based medicine

> >
Historically
( decision
Doctor knows best
approach
-
made
,




by physicians based on clinical
judgement / practicing the ar t



of medicine .
. . .




Symptom 8 Symptom Patterns Among Gulf War Registry Veterans


Personalised Medicine versus era of Us Trial and Error




A history of cancer chemotherapy

> The use of chemotherapy to treat cancer
began at the star t



of the 20th
century with attempts to nar row the universe



of chemicals that
might affect the disease by developing methods


to chemicals rodents
screen
using transplant able tumors in .




related
programs , and
> It was , however , four world war II -
the effects


evolved them provided establish
of drugs that from > that the impetus to


1955 the Cancer
in the national
drug development effort known as




Chemotherapy National Service centre .




3- principles of Serendip : Insight ,
chance and discovery in
qualitative research
,



what ?
changed
> Late 1960s onwards
questions asued which challenged if the


Doctor does
actually know best .
. .




( 1967) clinical
Feinstein judgement





-

Clinical reasoning and biases that affect it


°
Cocharane (197-2) Effectiveness and Efficiency :
Random Reflections

on health services

-
Lack clinical data
of to support practice


Eddy ( 1980s ) e.
g. Variations in
Physician practice : The role of uncertainty

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June 1, 2022
Number of pages
21
Written in
2021/2022
Type
Lecture notes
Professor(s)
David meredith
Contains
Lecture 1
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