LIPID DISORDERS
How lipid disorders come to attention
1 After a CV event such as Ml Stroke
2 Physical signs such as
Xanthe 1 as ma Yellow plagues around eyes more
common in women
Corneal arc us
Milky white
ring around
cornea
Tendon xanthoma Thickening
of tendons
Eruptive xanthoma Fleshy yellow1
white lumps T triglycerides
Palmar xanthoma fatty deposits on palms
Lipaemia retinal is White coloured vessels
, 3 Patient has a cute pancreatitis could be due to
gallstone
or alcoholism Occasionally caused by T triglycerides
4 Abnormal blood
Choosing who to test
Estimated risk 2 lot
Review regularly when over 40 lo
y
Patients with a family history of
Lipid disorders
Premature CV disease
As part of cascade screening
Mechanism of Ftl
Faulty LDL receptor majority
Faulty APO B100
PCS K 9 gain of function
Net result
How lipid disorders come to attention
1 After a CV event such as Ml Stroke
2 Physical signs such as
Xanthe 1 as ma Yellow plagues around eyes more
common in women
Corneal arc us
Milky white
ring around
cornea
Tendon xanthoma Thickening
of tendons
Eruptive xanthoma Fleshy yellow1
white lumps T triglycerides
Palmar xanthoma fatty deposits on palms
Lipaemia retinal is White coloured vessels
, 3 Patient has a cute pancreatitis could be due to
gallstone
or alcoholism Occasionally caused by T triglycerides
4 Abnormal blood
Choosing who to test
Estimated risk 2 lot
Review regularly when over 40 lo
y
Patients with a family history of
Lipid disorders
Premature CV disease
As part of cascade screening
Mechanism of Ftl
Faulty LDL receptor majority
Faulty APO B100
PCS K 9 gain of function
Net result
