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Lecture notes

The basics of DNA

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Lecture notes of 10 pages for the course Medicine at QUB (Genetics)










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Uploaded on
March 9, 2022
Number of pages
10
Written in
2020/2021
Type
Lecture notes
Professor(s)
Na
Contains
All classes

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BASES
Toatttached
phosphate to C3
attached
to




SEQUENCES Cs 3 direction
AGTTGCACG is shorthand for
S AGTTGCACG 3
senselcoding strand
3 TCAACGTGC S nonsenseltemplate strand

, R NA S A G UU G CA C G 3


DN A
packaging
Human 46 chromosomes
genome
2 m of DNA per cell


chromatin H itches
H 1 higher folding

Chromatin modifications
Affect
gene expression
can be passed onto cats
daughter epigenetics

REPLICATION
Un helix 2
Stages l winding of Building
strand in S 3 direction from
complementary
each strand 3 Join fragments on the
lagging
strand
DNA act as a template
for its own replication
semi conservative
replication Each
daughter strand contain
one conserved strand and one new strand
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