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Lecture notes

Cytoskeleton of cells

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Lecture notes of 11 pages for the course Medicine at QUB (Biochemistry)










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Uploaded on
March 9, 2022
Number of pages
11
Written in
2020/2021
Type
Lecture notes
Professor(s)
Na
Contains
All classes

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CYTOSKELETON Iii
protein filaments that extends
throughout
the
cytoplasm EUKARYOTIC CELLS
Have 3 main filaments
Intermediate filaments Ct
Microtubules
Actin microfilaments

Form a network of fibres
1 INTERMEDIATE in the cell that provide
tensilestrength They allow cells to resist external
forces such as stretching Main properties are

keratin vimen tin and I am ins Name from
comes

the size of the filaments in muscle in between actin
and myosin They are the toughest fibres in the cell
and have a role in
tethering cells to other cells
key

, IF fibres connect cells to
each other via contact points
known as DESMOSOMES
D es mo Somes allow
cells to form sheets
Epithelial
and
spread the stress points
on a cell to minimize damage due to mechanical strain


IFS are made of long twisted polymers of protein
Subunits




2monomers I dinner
Gives the lF
great
strength


412 dimers These IF tetramers

packedtogether to
8 2tetramers on to form a
go
helical array
containing 8 strands
of tetramers forming a rope like filament
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