NR546 FINAL EXAM STUDY GUIDE FOR
NURSING GRADE A+ COMPLETE EXAM
QUESTIONS AND 100% VERIFIED
ANSWERS (2026/2027) PASS
GUARANTEE
1. Whatmismthemmonoaminemhypothesismofmdepression?m-
mCORRECTmANSWERmItmtheorizesmthatmdepressionmismcausedmbymamdeficiencyminmmonoami
nemneurotransmission,mwhilemmaniamismduemtomanmexcess.
2. Whatmismamkeymprescribingmconsiderationmformantidepressantsminmbipolarmdisorder?m-
mCORRECTmANSWERmAntidepressantsmshouldmnotmbemgivenmasmmonotherapy;mtheymmustm
bemcombinedmwithmammoodmstabilizermtomavoidminducingmmania.
3. WhatmshouldmbemmonitoredmwhenmprescribingmSNRIsmtombreastfeedingmpatients?m-
mCORRECTmANSWERmInfantmirritability.
4. Whatmfactorsmshouldmbemconsideredmwhenmprescribingmantidepressants?m-
mCORRECTmANSWERmClientmpreference,mpriormtreatmentmresponse,manticipatedmadversem
effects,mcomorbidities,mhalf-life,minteractions,mandmcost.
5. Whatmshouldmbemdonemifmtheminitialmantidepressantmdoesmnotmwork?m-
mCORRECTmANSWERmFirst,mincreasemthemdose;mifmthatmfails,mswitchmtomamdifferentmdrugminm
themsamemclass,mthenmtrymamdrugminmamdifferentmclass,mandmpossiblymaddmamsecondmmedica
tion.
6. Whatmismthemrecommendedmdosemadjustmentmformoldermpatientsmtakingmcitaloprammandm
escitalopram?m-mCORRECTmANSWERmTheymshouldmreceivemhalfmthemusualmdose.
,7. WhichmSSRImhasmthemleastmCYPminteractions?m-
mCORRECTmANSWERmEscitalopramm(Lexapro).
8. WhichmSSRImismconsideredmgoodmformforgetfulmpatients?m-
mCORRECTmANSWERmFluoxetine,mduemtomitsm2-3mdaymhalf-life.
9. Whatmismthemlongest-actingmantidepressant?m-
mCORRECTmANSWERmFluoxetine,mwithmamhalf-lifemofm1-2mweeks.
10. Whatmismdiscontinuationmsyndromemandmwhichmmedicationmismmoremlikelymtomcausemit?m-
mCORRECTmANSWERmDiscontinuationmsyndromemoccursmwhenmstoppingmanmantidepressa
nt,mandmparoxetinemismmoremlikelymtomcausemit.
11. Whichmantidepressantmismsafemduringmnursingmandmpregnancy?m-
mCORRECTmANSWERmSertraline.
12. Whatmismserotoninmsyndrome?m-
mCORRECTmANSWERmAmconditionmthatmoccursmwhenmtwomserotonergicmdrugsmaremusedmto
gether,mleadingmtomsymptomsmsuchmasmmentalmstatusmchanges,mautonomicminstability,mne
uromuscularmsymptoms,mseizures,mandmgastrointestinalmsymptoms.
13. Whatmismthemtreatmentmformserotoninmsyndrome?m-
mCORRECTmANSWERmStopmthemmedication,mprovidemsupportivemcare,mandmusembenzodiaz
epines.
14. WhatmismthemblackmboxmwarningmformMAOIs?m-
mCORRECTmANSWERmTheymcarrymamwarningmformsuicidalmideationminmchildren,madolescents
,mandmyoungmadults.
15. Whatmismthemhalf-lifemofmMAOIs?m-mCORRECTmANSWERm2-4mhours.
, 16. WhatmismthemblackmboxmwarningmformSSRIs?m-
mCORRECTmANSWERmTheymcarrymamwarningmformsuicidalmtendencies.
17. WhatmaremMAOIsmandmwhatmdomtheyminhibit?m-
mCORRECTmANSWERmMAOIsm(monoaminemoxidaseminhibitors)maremantidepressantsmthatmi
nhibitmthemenzymemthatmdeactivatesmdopamine,mnorepinephrine,mandmserotonin.
18. WhatmcanmhappenmifmMAOIsmaremtakenmwithmtyramine-containingmfoods?m-
mCORRECTmANSWERmTheymcanmcausemamhypertensivemcrisis.
19. Whatmcanmincreasemlithiummlevels?m-mCORRECTmANSWERmNonsteroidalmanti-
inflammatorymdrugsm(NSAIDs)mandmangiotensin-convertingmenzymem(ACE)minhibitors.
20. Whatmcanmdecreasemlithiummlevels?m-mCORRECTmANSWERmCaffeinemandmmania.
21. WhatmismthemrolemofmL-Methylfolateminmdepressionmtreatment?m-
mCORRECTmANSWERmItmismnecessarymformthemsynthesismofmmonoaminesmandmismambioavaila
blemformmofmfolatemthatmentersmthembrain.
22. Whatmaremthemrecommendationsmformusingmparoxetinemduringmpregnancy?m-
mCORRECTmANSWERmParoxetinemismcontraindicatedmduemtomthemriskmofmcongenitalmdefects
,mincludingmatrialmseptalmdefects.
23. WhatmshouldmbemmonitoredmwhenmSNRIsmaremprescribedmtombreastfeedingmmothers?m-
mCORRECTmANSWERmInfantmirritability.
24. Howmdomoldermadultsmrespondmtomantidepressantsmcomparedmtomyoungermindividuals?m-
mCORRECTmANSWERmOldermadultsmmaymnotmrespondmasmrobustly,mespeciallymifmthemfirstme
pisodemofmdepressionmoccursmaftermagem65.
NURSING GRADE A+ COMPLETE EXAM
QUESTIONS AND 100% VERIFIED
ANSWERS (2026/2027) PASS
GUARANTEE
1. Whatmismthemmonoaminemhypothesismofmdepression?m-
mCORRECTmANSWERmItmtheorizesmthatmdepressionmismcausedmbymamdeficiencyminmmonoami
nemneurotransmission,mwhilemmaniamismduemtomanmexcess.
2. Whatmismamkeymprescribingmconsiderationmformantidepressantsminmbipolarmdisorder?m-
mCORRECTmANSWERmAntidepressantsmshouldmnotmbemgivenmasmmonotherapy;mtheymmustm
bemcombinedmwithmammoodmstabilizermtomavoidminducingmmania.
3. WhatmshouldmbemmonitoredmwhenmprescribingmSNRIsmtombreastfeedingmpatients?m-
mCORRECTmANSWERmInfantmirritability.
4. Whatmfactorsmshouldmbemconsideredmwhenmprescribingmantidepressants?m-
mCORRECTmANSWERmClientmpreference,mpriormtreatmentmresponse,manticipatedmadversem
effects,mcomorbidities,mhalf-life,minteractions,mandmcost.
5. Whatmshouldmbemdonemifmtheminitialmantidepressantmdoesmnotmwork?m-
mCORRECTmANSWERmFirst,mincreasemthemdose;mifmthatmfails,mswitchmtomamdifferentmdrugminm
themsamemclass,mthenmtrymamdrugminmamdifferentmclass,mandmpossiblymaddmamsecondmmedica
tion.
6. Whatmismthemrecommendedmdosemadjustmentmformoldermpatientsmtakingmcitaloprammandm
escitalopram?m-mCORRECTmANSWERmTheymshouldmreceivemhalfmthemusualmdose.
,7. WhichmSSRImhasmthemleastmCYPminteractions?m-
mCORRECTmANSWERmEscitalopramm(Lexapro).
8. WhichmSSRImismconsideredmgoodmformforgetfulmpatients?m-
mCORRECTmANSWERmFluoxetine,mduemtomitsm2-3mdaymhalf-life.
9. Whatmismthemlongest-actingmantidepressant?m-
mCORRECTmANSWERmFluoxetine,mwithmamhalf-lifemofm1-2mweeks.
10. Whatmismdiscontinuationmsyndromemandmwhichmmedicationmismmoremlikelymtomcausemit?m-
mCORRECTmANSWERmDiscontinuationmsyndromemoccursmwhenmstoppingmanmantidepressa
nt,mandmparoxetinemismmoremlikelymtomcausemit.
11. Whichmantidepressantmismsafemduringmnursingmandmpregnancy?m-
mCORRECTmANSWERmSertraline.
12. Whatmismserotoninmsyndrome?m-
mCORRECTmANSWERmAmconditionmthatmoccursmwhenmtwomserotonergicmdrugsmaremusedmto
gether,mleadingmtomsymptomsmsuchmasmmentalmstatusmchanges,mautonomicminstability,mne
uromuscularmsymptoms,mseizures,mandmgastrointestinalmsymptoms.
13. Whatmismthemtreatmentmformserotoninmsyndrome?m-
mCORRECTmANSWERmStopmthemmedication,mprovidemsupportivemcare,mandmusembenzodiaz
epines.
14. WhatmismthemblackmboxmwarningmformMAOIs?m-
mCORRECTmANSWERmTheymcarrymamwarningmformsuicidalmideationminmchildren,madolescents
,mandmyoungmadults.
15. Whatmismthemhalf-lifemofmMAOIs?m-mCORRECTmANSWERm2-4mhours.
, 16. WhatmismthemblackmboxmwarningmformSSRIs?m-
mCORRECTmANSWERmTheymcarrymamwarningmformsuicidalmtendencies.
17. WhatmaremMAOIsmandmwhatmdomtheyminhibit?m-
mCORRECTmANSWERmMAOIsm(monoaminemoxidaseminhibitors)maremantidepressantsmthatmi
nhibitmthemenzymemthatmdeactivatesmdopamine,mnorepinephrine,mandmserotonin.
18. WhatmcanmhappenmifmMAOIsmaremtakenmwithmtyramine-containingmfoods?m-
mCORRECTmANSWERmTheymcanmcausemamhypertensivemcrisis.
19. Whatmcanmincreasemlithiummlevels?m-mCORRECTmANSWERmNonsteroidalmanti-
inflammatorymdrugsm(NSAIDs)mandmangiotensin-convertingmenzymem(ACE)minhibitors.
20. Whatmcanmdecreasemlithiummlevels?m-mCORRECTmANSWERmCaffeinemandmmania.
21. WhatmismthemrolemofmL-Methylfolateminmdepressionmtreatment?m-
mCORRECTmANSWERmItmismnecessarymformthemsynthesismofmmonoaminesmandmismambioavaila
blemformmofmfolatemthatmentersmthembrain.
22. Whatmaremthemrecommendationsmformusingmparoxetinemduringmpregnancy?m-
mCORRECTmANSWERmParoxetinemismcontraindicatedmduemtomthemriskmofmcongenitalmdefects
,mincludingmatrialmseptalmdefects.
23. WhatmshouldmbemmonitoredmwhenmSNRIsmaremprescribedmtombreastfeedingmmothers?m-
mCORRECTmANSWERmInfantmirritability.
24. Howmdomoldermadultsmrespondmtomantidepressantsmcomparedmtomyoungermindividuals?m-
mCORRECTmANSWERmOldermadultsmmaymnotmrespondmasmrobustly,mespeciallymifmthemfirstme
pisodemofmdepressionmoccursmaftermagem65.
