ACG GI ACTUAL EXAM 2026 NEWEST VERSION
WITH COMPLETE QUESATIONS AND CORRECT
DETAILED ANSWERS|| LATEST UPDATE 2026-
2027 BRAND NEW!!
Diarrhea + PAS positive foamy macrophages on small bowel biopsy
+ POSITIVE acid fast stain
MAC
What is the mechanism of baclofen in GERD
Reduces TLESRs
HIV diarrhea + paresthesia in "saddle" distribution
HSV proctitis
,HIV + bloody diarrhea + "flask shaped" ulcers on biopsy
Entameba Histolytica
HIV + bloody diarrhea + "owl's eyes" inclusions on biopsy
CMV
Recurrent tongue swelling + fissured tongue + facial paralysis + non-
caseasting granulomas of tongue + diarrhea
Melkersson-Rosenthal syndrome (orofacial Crohn's)
Subepithelial gastric mass + 4th layer involvement + active positive +
CD117-negative
Leiomyoma
Acute lower abdominal pain in the setting of focal oval area of fat in
antimesteric border of the sigmoid colon on CT with central
attenuating line through inflamed fat
Epiploic Appendigitis
IDA + hemosiderinuria
Intravascular hemolysis
,Diarrhea + "congophilic angiopathy"
GI Amyloidosis
Diarrhea + high MCV + low B12 + high folate
SIBO
Dyspepsia + thick gastric folds + foveolar hyperplasia
Menetriere's disease
High transferrin saturation + Kupffer cells infiltrated with iron +
hepatocytes not infiltrated
Hemosiderosis from iron overload
Green-looking luminal nodule + myeloperoxidase positivity + high
LDH but no outright leukemia
Chloroma (high chance of developing leukemia)
Isolated fundic varices in setting of chronic panc
Splenic vein thrombosis
, Ascites + elevated bili + hepatomegaly + weight gain + bone marrow
transplant within previous 3 weeks
Veno-occlusive disease
Constipation with simultaneous increase in both rectal and anal
leads on ARM
Pelvic floor dysnergia
Hamartomatous polyps + protein losing enteropathy + diarrhea +
alopecia + dystrophic nails
Cronkhite-Canada
Weird oral projection + globus + dysphagia
Fibrovascular polyp
Gastric polyps with cystic dilations of oxyntic gland mucosa in
setting of PPI use
Fundic gland polyps
WITH COMPLETE QUESATIONS AND CORRECT
DETAILED ANSWERS|| LATEST UPDATE 2026-
2027 BRAND NEW!!
Diarrhea + PAS positive foamy macrophages on small bowel biopsy
+ POSITIVE acid fast stain
MAC
What is the mechanism of baclofen in GERD
Reduces TLESRs
HIV diarrhea + paresthesia in "saddle" distribution
HSV proctitis
,HIV + bloody diarrhea + "flask shaped" ulcers on biopsy
Entameba Histolytica
HIV + bloody diarrhea + "owl's eyes" inclusions on biopsy
CMV
Recurrent tongue swelling + fissured tongue + facial paralysis + non-
caseasting granulomas of tongue + diarrhea
Melkersson-Rosenthal syndrome (orofacial Crohn's)
Subepithelial gastric mass + 4th layer involvement + active positive +
CD117-negative
Leiomyoma
Acute lower abdominal pain in the setting of focal oval area of fat in
antimesteric border of the sigmoid colon on CT with central
attenuating line through inflamed fat
Epiploic Appendigitis
IDA + hemosiderinuria
Intravascular hemolysis
,Diarrhea + "congophilic angiopathy"
GI Amyloidosis
Diarrhea + high MCV + low B12 + high folate
SIBO
Dyspepsia + thick gastric folds + foveolar hyperplasia
Menetriere's disease
High transferrin saturation + Kupffer cells infiltrated with iron +
hepatocytes not infiltrated
Hemosiderosis from iron overload
Green-looking luminal nodule + myeloperoxidase positivity + high
LDH but no outright leukemia
Chloroma (high chance of developing leukemia)
Isolated fundic varices in setting of chronic panc
Splenic vein thrombosis
, Ascites + elevated bili + hepatomegaly + weight gain + bone marrow
transplant within previous 3 weeks
Veno-occlusive disease
Constipation with simultaneous increase in both rectal and anal
leads on ARM
Pelvic floor dysnergia
Hamartomatous polyps + protein losing enteropathy + diarrhea +
alopecia + dystrophic nails
Cronkhite-Canada
Weird oral projection + globus + dysphagia
Fibrovascular polyp
Gastric polyps with cystic dilations of oxyntic gland mucosa in
setting of PPI use
Fundic gland polyps
