1. What is usually seen on a CBC The CBC is usually normal unless a concurrent infection or
with an allergic disorder? inflammation is present.
2. What laboratory findings com- Elevated eosinophils and elevated total serum IgE.
monly support an allergic disor-
der?
3. What skin-testing methods may Intradermal, scratch, or prick testing at several sites.
be used to diagnose an allergy?
4. What is the most accurate confir- Skin testing.
mation of an allergy in the notes?
5. When should allergy skin testing During a period of bronchospasm.
not be performed?
6. What medications must be Corticosteroids and antihistamines (stopped 48-98 hrs pri-
stopped before allergy skin test- or) to prevent false-negative results.
ing, and why?
7. What is anaphylaxis? An immediate immunologic reaction between a specific
antigen and antibody.
, 8. What begins the allergic reaction An allergen cross-links with allergen-specific IgE antibod-
in anaphylaxis? ies.
9. Where are allergen-specific IgE On the surface membranes of mast cells and basophils.
antibodies located?
10. Where are mast cells commonly In the respiratory and gastrointestinal tracts.
located?
11. What happens after an allergen Cellular degranulation occurs.
cross-links IgE on mast cells and
basophils?
12. Which mediators are released Histamine, prostaglandins, and other bioactive mediators.
during anaphylactic degranula-
tion?
with an allergic disorder? inflammation is present.
2. What laboratory findings com- Elevated eosinophils and elevated total serum IgE.
monly support an allergic disor-
der?
3. What skin-testing methods may Intradermal, scratch, or prick testing at several sites.
be used to diagnose an allergy?
4. What is the most accurate confir- Skin testing.
mation of an allergy in the notes?
5. When should allergy skin testing During a period of bronchospasm.
not be performed?
6. What medications must be Corticosteroids and antihistamines (stopped 48-98 hrs pri-
stopped before allergy skin test- or) to prevent false-negative results.
ing, and why?
7. What is anaphylaxis? An immediate immunologic reaction between a specific
antigen and antibody.
, 8. What begins the allergic reaction An allergen cross-links with allergen-specific IgE antibod-
in anaphylaxis? ies.
9. Where are allergen-specific IgE On the surface membranes of mast cells and basophils.
antibodies located?
10. Where are mast cells commonly In the respiratory and gastrointestinal tracts.
located?
11. What happens after an allergen Cellular degranulation occurs.
cross-links IgE on mast cells and
basophils?
12. Which mediators are released Histamine, prostaglandins, and other bioactive mediators.
during anaphylactic degranula-
tion?
