Expert Verifed Ace the Test
Microcytic anemia - ANSWER ✔✔iron deficiency, usually due to
malabsorption / occult blood loss, or lead poisoning. MCV <80
Normocytic anemia - ANSWER ✔✔due to hemorrhage or chronic
disease. Aplastic anemia. MVC 80-92
macrocytic anemia - ANSWER ✔✔due to folate or vitamin
B12(cobalamin) deficiency (megaloblastic anemia) / pernicious anemia.
/liver diseases
serum ferritin - ANSWER ✔✔Tests for iron stores. As serum ferritin
falls, TIBC rises, and serum iron levels will eventually fall.
,Anemia of chronic disease - ANSWER ✔✔NORMOcytic anemia with
↓ serum iron, ↓ TIBC, and normal iron stores. Treat with epoetin and give
an iron supplement
Schistocytes - ANSWER ✔✔Associated with hemolytic uremia
syndrome
pernicious anemia - ANSWER ✔✔Macrocytic anemia caused by
vitamin B12 deficiency. B12 is essential to maturation of erythrocytes -
low levels will cause the RBC to expand. PPIs and histamine2 blockers
can cause this.
Increased homocysteine & methylmalonic acid level indicates ? -
ANSWER ✔✔B12 deficiency
increased homocysteine levels - ANSWER ✔✔Folate deficiency
Sperocytes - ANSWER ✔✔Appear as spheres, lack central pallor,
smaller diameter, indicate immune-mediated process - can be seen after
blood transfusion
aplastic anemia - ANSWER ✔✔a normocytic anemia characterized
by the failure of bone marrow to produce red blood cells
Low ferritin - ANSWER ✔✔iron deficiency anemia
, Transferrin - ANSWER ✔✔transports iron
TIBC (total iron binding capacity) - ANSWER ✔✔Available transferrin
that is left unbound (Represents the "empty seats on a train"). When iron
is low, TIBC will be high. When iron is high, TIBC will be low
MCHC (mean corpuscular hemoglobin concentration) - ANSWER
✔✔32 - 36 g/dL
Concentration of hemoglobin per RBC
Alzheimer's disease - ANSWER ✔✔Gradual onset with early memory
impairment. Most common form of dementia. Cholinesterase inhibitors
for early treatment.
Lewy body dementia - ANSWER ✔✔usually a rapidly progressive
form of dementia seen with Parkinson syndrome. - VISUAL
HALLUCINATION ARE SEEN.
frontal lobe dementia - ANSWER ✔✔Seen before age 60 w
personality impairments. PDG-PET Scan testing. - decreased glucose
uptake by the brain in frontal and temporal lobe
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