MMLT 1410 Module 6 Exam Questions and
Answers with Verified Solutions | Latest
Updated 2026
autograft transplantation of healthy tissue from one
site to
another site in the same individual
Syngraft transplant between identical twins
allograft transplantation of healthy tissue from one
person
to another person; also called homograft
xenograft transplantation (dermis only) from a foreign
donor
(usually a pig) and transferred to a human;
also
called heterograft
First set rejection Tissue initially appears accepted
In a few days, the skin takes on a purple
hue due to
necrosis
Symptoms: loss of organ function, fever,
malaise
Due to cell mediated immunity
, Second set rejection happen after the same donor tissue is
transplanted
onto the same recipient as the first-set
rejection.
Hyperacute rejection response to nonhuman Ag
Host antibodies attack the donor tissue
Complement is activated, & the
transplanted tissue
gets lysed
ABO group ag. or MHC class I ag
Process can occur within minutes
accelerated rejection usually occurs within days and is due to a
memory
or anamnestic response to pre-formed
antibodies
directed against mismatched donor
antigen which
are absent at the time of transplantation.
Improved
antibody screening and identification
techniques as
well as improvements in crossmatch
techniques
have significantly reduced the incidence of
hyperacute and accelerated rejection.
Acute rejection predominantly a cell-mediated reaction,
MC
reaction
Answers with Verified Solutions | Latest
Updated 2026
autograft transplantation of healthy tissue from one
site to
another site in the same individual
Syngraft transplant between identical twins
allograft transplantation of healthy tissue from one
person
to another person; also called homograft
xenograft transplantation (dermis only) from a foreign
donor
(usually a pig) and transferred to a human;
also
called heterograft
First set rejection Tissue initially appears accepted
In a few days, the skin takes on a purple
hue due to
necrosis
Symptoms: loss of organ function, fever,
malaise
Due to cell mediated immunity
, Second set rejection happen after the same donor tissue is
transplanted
onto the same recipient as the first-set
rejection.
Hyperacute rejection response to nonhuman Ag
Host antibodies attack the donor tissue
Complement is activated, & the
transplanted tissue
gets lysed
ABO group ag. or MHC class I ag
Process can occur within minutes
accelerated rejection usually occurs within days and is due to a
memory
or anamnestic response to pre-formed
antibodies
directed against mismatched donor
antigen which
are absent at the time of transplantation.
Improved
antibody screening and identification
techniques as
well as improvements in crossmatch
techniques
have significantly reduced the incidence of
hyperacute and accelerated rejection.
Acute rejection predominantly a cell-mediated reaction,
MC
reaction
