2027) UPDATE EXAM 130 QUESTIONS WITH
MULTIPLE CHOICES VERIFIED & REVISED
ANSWERS (NEW)!!
____________ drugs cross the placenta most readily. - CORRECT ANSWER: a. Lipid soluble
...tinibs, and others - CORRECT ANSWER: -tinib = tyrosine kinase inhibitors canertinib;
imatinib; mubritinib
-olol = beta-blockers (propranolol type) timolol; atenolol
vastatin = antidyslipidemics (HMG-CoA inhibitors) atorvastatin; lovastatin; pravastatin
pril = antihypertensives (ACE inhibitors) enalapril
*Post ganglionic sympathetic neurons* that have acetylcholine (ACh) as the neurotransmitter,
cause what physiologic response when stimulated? - CORRECT ANSWER: Sweating
A nurse prepares to administer a newly prescribed medication to a 22 year old woman. The
medication package insert states that it is a "FDA Pregnancy Category X" drug. Which is the
nurse's best action?
a. Ask the patient, "Have you been sexually active during the past year?"
b. Ask the patient, "When was your last menstrual period?"
c. Inform the patient of the primary actions of the medication.
d. Assess the patient for a history of sexually transmitted infections (STIs) - CORRECT
ANSWER: b. Ask the patient, "When was your last menstrual period?"
Acetylcholine - CORRECT ANSWER: A neurotransmitter present at all preganglionic ANS
(adrenergic [sympathetic] and cholinergic [parasympathetic]) receptors (synapses), all post-
ganglionic cholinergic (parasympathetic) receptors, the post ganglionic adrenergic (sympathetic)
,receptors to sweat glands, and at the myoneural (neuromuscular) junction of all somatic (motor
system) receptors.
Acetylcholinesterase - CORRECT ANSWER: Naturally occurring substance that metabolizes
acetylcholine so as to inactivate it, and cease its synaptic neurotransmitter function.
Addiction - CORRECT ANSWER: A type of *adverse drug reaction characterized by
maladaptive behaviors concerning the use of a substance that is no longer medically necessary*.
These behaviors include the continued use of the specific substance despite the realization that it
is causing adverse consequences to the patient, as well as a loss of control over and
preoccupation with the use of the substance.
Adverse Drug Reaction - CORRECT ANSWER: A type of adverse drug event characterized by
an *unintended/undesired effect*. It usually occurs with ordinary, not abnormally high doses.
*ADRs are often predictable based on previous experience with the drug*, but the first few times
a new ADR is reported, the cause effect relationship may not have been established.
After a nurse gives the recommended dosage of a new medication with known gastrointestinal
side effects to a patient, nausea and one episode of vomiting occur in the patient. Which term
below best characterizes this response? - CORRECT ANSWER: adverse effect
Agonist - CORRECT ANSWER: drug that mimics the action of or creates the same effect as an
endogenous substance (e.g., a neurotransmitter or a hormone).
Allergic Reaction - CORRECT ANSWER: A type of adverse reaction that is due to an abnormal
immunologic reaction. Occurs only in people who have BOTH been exposed to the substance (to
which the reaction occurs) previously and have some predisposing allergy-prone condition.
Alpha 1 - CORRECT ANSWER: Adrenergnic- can be triggered by NE, Epi, D
Mydriasis (dialation)
Constrict vascular smooth muscle--> Increase BP
, Ejaculation
Constrict bladder neck and prostate
An ingredient of grapefruit juice may cause a drug interaction due to? - CORRECT ANSWER:
inhibition of CYP3A4
Antagonist - CORRECT ANSWER: drug that prevents the activation of a receptor by or blocks
the receptor of an endogenous substance or an agonist drug. An agonist must be present.
Autonomic Nervous System - CORRECT ANSWER: A part of the peripheral nervous system
that is under involuntary control ie: a person can not control its action
Basic mechanism of neuropharmacologic agents - CORRECT ANSWER: Axonal conduction
Action potential down the axon
Synaptic transmission
Information carried across the neuron gap to the postsynaptic cell
This cell may be another nerve cell or an effector organ.
Beta 1 - CORRECT ANSWER: Adrenergic- can be triggered by NE, Epi, D
(Kick start the heart!)
Increase Heart rate
Increase force of constriction
Increase velocity of conduction in AV node
Increase lipolysis
Increase renin release (start RAA)
Beta 2 - CORRECT ANSWER: Adrenergic- can be triggered by Epi,
Bronchial dilation