Test Bank
for
Lehninger Principles of Biochemistry
Fourth Edition
TBRRYSPLALT
EUGENE BARBER
David L. Nelson
Brook Chase Soltvedt
W. H. Freeman and Company
New York
, Contents
Chapter 1: The Foundations of Biochemistry. |
Chapter 2: Water, 12
Chapter 3: Amino Acids, Peptides, and Proteins, 21
Chapter 4: The Three-Dimensional Structure of Proteins, 38
Chapter 5: Protein Function, 51
Chapter 6: Enzymes, 60
Chapter 7: Carbohydrates and Glycobiology, 80
Chapter 8: Nucleotides and Nucleic Acids, 89
Chapter 9: DNA-Based Information Technologies, 101
Chapter 10 : Lipids, 110
Chapter 11: Biological Membranes and Transport, 118
Chapter 12 : Biosignaling, 133
Chapter 13 : Principles of Bioenergetics, 145
Chapter 14 : Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway, 157
Chapter 15 : Principles of Metabolic Regulation, 176
Chapter 16 aLhe Citric Acid Cycle, 185
Chapter 17 : Fatty Acid Catabolism
Chapter 18 : Amino Acid Oxidation and the Production of Urea, 210
Chapter 19 : Oxidative Phosphorylation and Photophosphorylation, 220
Chapter 20 : Carbohydrate Biosynthesis in Plants and Bacteria, 238
Chapter 21 : Lipid Biosynthesis, 248
Chapter 22 : Biosynthesis of Amino Acids, Nucleotides, and Related Molecules, 259
Chapter 23 : Hormonal Regulation and Integration of Mammalian Metabolism, 272
Chapter 24 : Genes and Chromosomes, 280
Chapter 25 : DNA Metabolism, 289
Chapter 26 : RNA Metabolism, 301
Chapter 27 : Protein Metabolism, 313
Chapter 28 : Regulation of Gene Expression, 326
,SS SSS SSS
Chapter 1 The Foundations of Biochemistry
$a SSS
Multiple Choice Questions
1. Cellular foundations
Pages: 3-4 Difficulty: 1 Ans: C
In a bacterial cell, the DNA is in the:
A) cell envelope.
B) cell membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.
Cellular foundations
Page: 4 Difficulty: 1 Ans: E
A major change occurring in the evolution of eukaryotes from prokaryotes was the development of:
A) DNA.
B) photosynthetic capability.
C) plasma membranes.
D) ribosomes.
E) the nucleus.
Cellular foundations
Page: 4 ‘Difficulty: 1 Ans: B
In eukaryotes, the nucleus is enclosed by a double membrane called the:
A) cell membrane.
B) nuclear envelope.
C) nucleolus.
D) nucleoplasm.
E) nucleosome.
Cellular foundations
Page: 4 Difficulty: 1 Ans: C
The dimensions of living cells are limited, on the lower end by the minimum number of biomolecules
necessary for function, and on the upper end by the rate of diffusion of solutes such as oxygen.
Except for highly elongated cells, they usually have lengths and diameters in the range of:
A) 0.1 pum to 10 pm.
B) 0.3 pm to 30 pm.
C) 0.3 pm to 100 pm.
D) 1 pum to 100 pm.
E) 1pm to 300 um.
, Chapter 1 The Foundations of Biochemistry
Cellular foundations
Page:5 _—Difficulty:2 Ans: B 7
The bacterium E. coli requires simple organic molecules for growth and energy—it is therefore a:
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) photoautotroph.
E) photoheterotroph.
Cellular foundations
Page: 10 Difficulty: 2 Ans: B
Which one of the following has the cellular components arranged in order of increasing size?
A) Amino acid < protein < mitochondrion < ribosome
B) Amino acid < protein < ribosome < mitochondrion
C) Amino acid < ribosome < protein < mitochondrion
D) Protein < amino acid < mitochondrion < ribosome
E) Protein < ribosome < mitochondrion < amino acid
Cellular foundations
Page: 11 Difficulty: 2 Ans: A
The three-dimensional structure of macromolecules is formed and maintained primarily through
noncovalent interactions. Which one of the following is not considered a noncovalent interaction?
A) carbon-carbon bonds
B) hydrogen bonds
C) hydrophobic interactions
D) ionic interactions
E) van der Waals interactions
Chemical foundations
Page: 12 Difficulty: 2 Ans: E
Which one of the following is not among the four most abundant elements in living organisms?
A) Carbon
B) Hydrogen
C) Nitrogen
D) Oxygen
E) Phosphorus
Chemical foundations
Page: 13 Difficulty: 1 Ans: B
The four covalent bonds in methane (CH,) are arranged around carbon to give which one of the
following geometries?
A) linear
B) tetrahedral
C) trigonal bipyramidal
D) trigonal planar
E) trigonal pyramidal
for
Lehninger Principles of Biochemistry
Fourth Edition
TBRRYSPLALT
EUGENE BARBER
David L. Nelson
Brook Chase Soltvedt
W. H. Freeman and Company
New York
, Contents
Chapter 1: The Foundations of Biochemistry. |
Chapter 2: Water, 12
Chapter 3: Amino Acids, Peptides, and Proteins, 21
Chapter 4: The Three-Dimensional Structure of Proteins, 38
Chapter 5: Protein Function, 51
Chapter 6: Enzymes, 60
Chapter 7: Carbohydrates and Glycobiology, 80
Chapter 8: Nucleotides and Nucleic Acids, 89
Chapter 9: DNA-Based Information Technologies, 101
Chapter 10 : Lipids, 110
Chapter 11: Biological Membranes and Transport, 118
Chapter 12 : Biosignaling, 133
Chapter 13 : Principles of Bioenergetics, 145
Chapter 14 : Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway, 157
Chapter 15 : Principles of Metabolic Regulation, 176
Chapter 16 aLhe Citric Acid Cycle, 185
Chapter 17 : Fatty Acid Catabolism
Chapter 18 : Amino Acid Oxidation and the Production of Urea, 210
Chapter 19 : Oxidative Phosphorylation and Photophosphorylation, 220
Chapter 20 : Carbohydrate Biosynthesis in Plants and Bacteria, 238
Chapter 21 : Lipid Biosynthesis, 248
Chapter 22 : Biosynthesis of Amino Acids, Nucleotides, and Related Molecules, 259
Chapter 23 : Hormonal Regulation and Integration of Mammalian Metabolism, 272
Chapter 24 : Genes and Chromosomes, 280
Chapter 25 : DNA Metabolism, 289
Chapter 26 : RNA Metabolism, 301
Chapter 27 : Protein Metabolism, 313
Chapter 28 : Regulation of Gene Expression, 326
,SS SSS SSS
Chapter 1 The Foundations of Biochemistry
$a SSS
Multiple Choice Questions
1. Cellular foundations
Pages: 3-4 Difficulty: 1 Ans: C
In a bacterial cell, the DNA is in the:
A) cell envelope.
B) cell membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.
Cellular foundations
Page: 4 Difficulty: 1 Ans: E
A major change occurring in the evolution of eukaryotes from prokaryotes was the development of:
A) DNA.
B) photosynthetic capability.
C) plasma membranes.
D) ribosomes.
E) the nucleus.
Cellular foundations
Page: 4 ‘Difficulty: 1 Ans: B
In eukaryotes, the nucleus is enclosed by a double membrane called the:
A) cell membrane.
B) nuclear envelope.
C) nucleolus.
D) nucleoplasm.
E) nucleosome.
Cellular foundations
Page: 4 Difficulty: 1 Ans: C
The dimensions of living cells are limited, on the lower end by the minimum number of biomolecules
necessary for function, and on the upper end by the rate of diffusion of solutes such as oxygen.
Except for highly elongated cells, they usually have lengths and diameters in the range of:
A) 0.1 pum to 10 pm.
B) 0.3 pm to 30 pm.
C) 0.3 pm to 100 pm.
D) 1 pum to 100 pm.
E) 1pm to 300 um.
, Chapter 1 The Foundations of Biochemistry
Cellular foundations
Page:5 _—Difficulty:2 Ans: B 7
The bacterium E. coli requires simple organic molecules for growth and energy—it is therefore a:
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) photoautotroph.
E) photoheterotroph.
Cellular foundations
Page: 10 Difficulty: 2 Ans: B
Which one of the following has the cellular components arranged in order of increasing size?
A) Amino acid < protein < mitochondrion < ribosome
B) Amino acid < protein < ribosome < mitochondrion
C) Amino acid < ribosome < protein < mitochondrion
D) Protein < amino acid < mitochondrion < ribosome
E) Protein < ribosome < mitochondrion < amino acid
Cellular foundations
Page: 11 Difficulty: 2 Ans: A
The three-dimensional structure of macromolecules is formed and maintained primarily through
noncovalent interactions. Which one of the following is not considered a noncovalent interaction?
A) carbon-carbon bonds
B) hydrogen bonds
C) hydrophobic interactions
D) ionic interactions
E) van der Waals interactions
Chemical foundations
Page: 12 Difficulty: 2 Ans: E
Which one of the following is not among the four most abundant elements in living organisms?
A) Carbon
B) Hydrogen
C) Nitrogen
D) Oxygen
E) Phosphorus
Chemical foundations
Page: 13 Difficulty: 1 Ans: B
The four covalent bonds in methane (CH,) are arranged around carbon to give which one of the
following geometries?
A) linear
B) tetrahedral
C) trigonal bipyramidal
D) trigonal planar
E) trigonal pyramidal
