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NR 507 Week 6 Endocrine System Advanced Pathophysiology 2026/2027 – Study Guide

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Comprehensive 2026/2027 NR 507 Week 6 study guide on the Endocrine System (Advanced Pathophysiology). Includes key concepts, hormone regulation, disease mechanisms, and practice questions with rationales to help nurse practitioner students master endocrine pathophysiology and excel in exams.

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Advanced Pathophysiology
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Institution
Advanced Pathophysiology
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Advanced Pathophysiology

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Uploaded on
January 24, 2026
Number of pages
120
Written in
2025/2026
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NR 507System
Week 6
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Pathophysiology).pdf
System (Advanced Pathophysiology).pdf




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Advanced Pathophysiology (Chamberlain University)




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ENDOCRENE

The pineal gland is responsible for regulating the sleep-wake cycle.

It must be bound to a protein and it bind to receptors on the cell membrane rather than inside
the cell membrane.

The anterior lobe of the pituitary produces its own hormones.


The endocrine cell can also secrete hormones that target cells directly close it. When this
occurs, this type of secretion is known as paracrine signaling.

This statement is true. Lipid-derived hormones cross the cell membrane and bind to receptors
in the cell’s cytoplasm.

Aldosterone promotes sodium reabsorption and potassium excretion in the kidneys.
They are located on the posterior lobes of the thyroid gland.

The posterior pituitary receives its hormones (oxytocin and ADH) from the hypothalamus. The
anterior pituitary produces its own hormones.

ADH is the only hormone listed that is produced by the hypothalamus.


The only steroid hormone listed is testosterone.




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Overview of the Endocrine System
The purpose of the endocrine system is to maintain the body’s homeostasis using hormones.
Hormones are signaling molecules. Although a wide variety of hormones function within the
body, they share certain general characteristics:

1. Hormones have speci昀椀c rates and rhythms of secretion. Three basic secretion patterns
are: (1) circadian or diurnal patterns, (2) pulsatile and cyclic patterns, and (3) patterns
that depend on levels of circulating substrates (e.g., calcium, sodium, potassium, or the
hormones themselves).
2. Hormones operate within feedback systems, either positive or negative, to maintain an
optimal internal environment.
3. Hormones a昀昀ect only cells with speci昀椀c receptors and then act on those cells to initiate
speci昀椀c cell functions or activities.

When an endocrine cell receives a stimulus or command, this stimulates the endocrine cell to
secrete hormones into the blood stream. The hormones will then target and bind onto a
speci昀椀c receptor on a target cell. This will cause the target cell to initiate a response as shown
in the diagram below:




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Signaling Hormones



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