1|Page
APEA Pharmacology Actual Exam Newest Actual Exam With
Complete 100 Questions And Correct Detailed Answers
(Verified Answers) |Already Graded A+
Once you graduate from an NP program, in order to prescribe you'll
need: - ANSWERS---Advanced nurse prescriber license
-DEA #
What is the purpose of a DEA #? - ANSWERS--Needed to prescribed
scheduled drugs
Rules for prescribing Schedule II drugs: - ANSWERS---Written script
needed
-1 month supply only
-No refills
What is the PDMP? - ANSWERS--Prescription Drug Monitoring
Program
Used to effectively track patient's controlled substance uses across
different health facilities (in the same state)
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What are clinical practice guidelines? - ANSWERS--Recommendations
that are intended to optimize patient care that are informed by a
systematic review of the evidence and an assessment of the
benefits/harms of alternative care practices
Ex: sepsis, CAP
Common causes of medication errors: - ANSWERS---Illegible writing
-Drug names that sound alike
-Medications that look alike
-Administering a drug with the wrong route
What is pharmacokinetics? What are its 4 categories? - ANSWERS--
What the body does to the drug
1. Absorption
2. Metabolism
3. Distribution
4. Excretion
Quickest route of absorption? Slowest? - ANSWERS--IV = quickest
IM = slowest
What is the most common way drugs pass through cell membranes?
- ANSWERS--Passive diffusion
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What characteristics of a drug allow it to pass most quickly through
cell membranes (usually through passive diffusion)? - ANSWERS--
Small, uncharged (unionized), lipid soluble--pass through membrane
without any energy
What does it mean when a drug is ionized? - ANSWERS--It means
that the drug is stuck in the compartment it was ionized in and has to
be moved to the next compartment (cannot be absorbed into the
bloodstream)
Where do weak acids absorb? - ANSWERS--Stomach
Where do weak bases absorb? - ANSWERS--Small intestine
pH of stomach: - ANSWERS--2-4
pH of small intestine: - ANSWERS--6-7
pH of large intestine: - ANSWERS--6-7
pH of bloodstream: - ANSWERS--7.35-7.45
pH of bladder: - ANSWERS--5-8
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pH of breastmilk: - ANSWERS--7.1
Where will a drug absorb if it is a weak base that ionizes at a pH of 4
and lower? - ANSWERS--In the small intestine (since the stomach has
a pH of 2-4, so the drug will become ionized and move to the small
intestine where it will be able to absorb into the bloodstream)
How can we manipulate the urine pH in cases of overdose? -
ANSWERS--Drugs that are weak acids (aspirin) can be trapped and
excreted through the urine.
We raise pH of the urine (with sodium bicarb) to force the drug to
ionize and allow it to be excreted, not reabsorbed through the
bloodstream.
What is distribution? - ANSWERS--How a drug will be transported to
the tissues it needs to go to in order for it to exert its effects
Drug factors related to distribution: - ANSWERS---Lipid solubility
-Molecular size
-Degree of ionization
-Duration of action
-Cellular binding
-Therapeutic effects
-Toxic effects
APEA Pharmacology Actual Exam Newest Actual Exam With
Complete 100 Questions And Correct Detailed Answers
(Verified Answers) |Already Graded A+
Once you graduate from an NP program, in order to prescribe you'll
need: - ANSWERS---Advanced nurse prescriber license
-DEA #
What is the purpose of a DEA #? - ANSWERS--Needed to prescribed
scheduled drugs
Rules for prescribing Schedule II drugs: - ANSWERS---Written script
needed
-1 month supply only
-No refills
What is the PDMP? - ANSWERS--Prescription Drug Monitoring
Program
Used to effectively track patient's controlled substance uses across
different health facilities (in the same state)
,2|Page
What are clinical practice guidelines? - ANSWERS--Recommendations
that are intended to optimize patient care that are informed by a
systematic review of the evidence and an assessment of the
benefits/harms of alternative care practices
Ex: sepsis, CAP
Common causes of medication errors: - ANSWERS---Illegible writing
-Drug names that sound alike
-Medications that look alike
-Administering a drug with the wrong route
What is pharmacokinetics? What are its 4 categories? - ANSWERS--
What the body does to the drug
1. Absorption
2. Metabolism
3. Distribution
4. Excretion
Quickest route of absorption? Slowest? - ANSWERS--IV = quickest
IM = slowest
What is the most common way drugs pass through cell membranes?
- ANSWERS--Passive diffusion
,3|Page
What characteristics of a drug allow it to pass most quickly through
cell membranes (usually through passive diffusion)? - ANSWERS--
Small, uncharged (unionized), lipid soluble--pass through membrane
without any energy
What does it mean when a drug is ionized? - ANSWERS--It means
that the drug is stuck in the compartment it was ionized in and has to
be moved to the next compartment (cannot be absorbed into the
bloodstream)
Where do weak acids absorb? - ANSWERS--Stomach
Where do weak bases absorb? - ANSWERS--Small intestine
pH of stomach: - ANSWERS--2-4
pH of small intestine: - ANSWERS--6-7
pH of large intestine: - ANSWERS--6-7
pH of bloodstream: - ANSWERS--7.35-7.45
pH of bladder: - ANSWERS--5-8
, 4|Page
pH of breastmilk: - ANSWERS--7.1
Where will a drug absorb if it is a weak base that ionizes at a pH of 4
and lower? - ANSWERS--In the small intestine (since the stomach has
a pH of 2-4, so the drug will become ionized and move to the small
intestine where it will be able to absorb into the bloodstream)
How can we manipulate the urine pH in cases of overdose? -
ANSWERS--Drugs that are weak acids (aspirin) can be trapped and
excreted through the urine.
We raise pH of the urine (with sodium bicarb) to force the drug to
ionize and allow it to be excreted, not reabsorbed through the
bloodstream.
What is distribution? - ANSWERS--How a drug will be transported to
the tissues it needs to go to in order for it to exert its effects
Drug factors related to distribution: - ANSWERS---Lipid solubility
-Molecular size
-Degree of ionization
-Duration of action
-Cellular binding
-Therapeutic effects
-Toxic effects
