RN HESI PHARMACOLOGY EXAM 2026 FULL
PREPARATION WITH CORRECT ANSWERS
◉ A health care provider prescribes famotidine for a client with
dyspepsia. Which statement is important to include in a teaching
session about famotidine?
A. Lowers the stress level
B. Neutralizes gastric acidity
C. Reduces gastrointestinal peristalsis
D. Decreases secretions in the stomach Answer: D. Decreases
secretions in the stomach
◉ Famotidine is prescribed for a client with peptic ulcer disease.
Which mechanism of action is a characteristic of this medication?
A. Increases gastric motility
B. Neutralizes gastric acidity
C. Facilitates histamine release
D. Inhibits gastric acid secretion Answer: D. Inhibits gastric acid
secretion
◉ The nurse is providing medication teaching for a client prescribed
famotidine for the treatment of gastroesophageal reflux disease
,(GERD). Which statement by the client indicates an understanding of
the teaching?
A. I will take this medication once a day in the morning
B. I will no longer have discomfort at night once I begin this
medication
C. This medication will both prevent and treat heartburn
D. My treatment will be done in one week Answer: C. This
medication will both prevent and treat heartburn
◉ The nurse is counseling a client with gastroesophageal reflux
disease (GERD) who has been taking prescribed famotidine for two
days. Which statement would require immediate follow up by a
healthcare provider?
A. I take digoxin for my heart failure
B. I use calcium carbonate if I have symptoms after meals
C. I use alendronate for my osteoporosis
D. I'm still having some symptoms of heartburn. Answer: A. I take
digoxin for my heart failure
◉ The nurse administers cimetidine to a 75-year-old client
diagnosed with a gastric ulcer. The nurse should monitor the client
for which adverse reaction?
A. Mental status change
B. Increased liver enzymes
,C. Constipation
D. Hearing loss Answer: A. Mental status change
◉ A nurse administers cimetidine to a 79-year-old male with a
gastric ulcer. Which parameter may be affected by this drug and
should be closely monitored by the nurse?
A. Blood pressure
B. Liver enzymes
C. Mental status
D. Hemoglobin Answer: C. Mental status
◉ Which mechanism is specifically responsible for the action of the
medication ranitidine?
A. Inhibiting proton pumps
B. Promoting the release of gastrin
C. Regenerating the gastric mucosa
D. Inhibiting the histamine at H 2 receptors Answer: D. Inhibiting the
histamine at H 2 receptors
◉ Which administration instruction would the nurse give a client
prescribed ranitidine 150 mg daily to treat peptic ulcer disease
(PUD)?
A. As needed
, B. With meals
C. At bedtime
D. Before meals Answer: C. At bedtime
◉ Which information would the nurse include when teaching a
client about the administration of ranitidine?
A. Ranitidine increases gastrointestinal peristalsis.
B. Ranitidine reduces gastric acidity in the stomach.
C. Ranitidine neutralizes the acid that is present in the stomach.
D. Ranitidine stops the production of hydrochloric acid in the
stomach. Answer: B. Ranitidine reduces gastric acidity in the
stomach.
◉ Which concern would prompt the nurse to contact the health care
provider when a client with gastric ulcers receives a prescription for
ranitidine 150 mg twice a day?
A. Ranitidine can increase the risk for gastrointestinal bleeding.
B. An administration route is not specified.
C. Ranitidine is contraindicated for gastric ulcers.
D. Ranitidine should be given with an adjuvant. Answer: B. An
administration route is not specified.
◉ Which medication is classified as an H 2 receptor antagonist?
Select all that apply. One, some, or all responses may be correct.
PREPARATION WITH CORRECT ANSWERS
◉ A health care provider prescribes famotidine for a client with
dyspepsia. Which statement is important to include in a teaching
session about famotidine?
A. Lowers the stress level
B. Neutralizes gastric acidity
C. Reduces gastrointestinal peristalsis
D. Decreases secretions in the stomach Answer: D. Decreases
secretions in the stomach
◉ Famotidine is prescribed for a client with peptic ulcer disease.
Which mechanism of action is a characteristic of this medication?
A. Increases gastric motility
B. Neutralizes gastric acidity
C. Facilitates histamine release
D. Inhibits gastric acid secretion Answer: D. Inhibits gastric acid
secretion
◉ The nurse is providing medication teaching for a client prescribed
famotidine for the treatment of gastroesophageal reflux disease
,(GERD). Which statement by the client indicates an understanding of
the teaching?
A. I will take this medication once a day in the morning
B. I will no longer have discomfort at night once I begin this
medication
C. This medication will both prevent and treat heartburn
D. My treatment will be done in one week Answer: C. This
medication will both prevent and treat heartburn
◉ The nurse is counseling a client with gastroesophageal reflux
disease (GERD) who has been taking prescribed famotidine for two
days. Which statement would require immediate follow up by a
healthcare provider?
A. I take digoxin for my heart failure
B. I use calcium carbonate if I have symptoms after meals
C. I use alendronate for my osteoporosis
D. I'm still having some symptoms of heartburn. Answer: A. I take
digoxin for my heart failure
◉ The nurse administers cimetidine to a 75-year-old client
diagnosed with a gastric ulcer. The nurse should monitor the client
for which adverse reaction?
A. Mental status change
B. Increased liver enzymes
,C. Constipation
D. Hearing loss Answer: A. Mental status change
◉ A nurse administers cimetidine to a 79-year-old male with a
gastric ulcer. Which parameter may be affected by this drug and
should be closely monitored by the nurse?
A. Blood pressure
B. Liver enzymes
C. Mental status
D. Hemoglobin Answer: C. Mental status
◉ Which mechanism is specifically responsible for the action of the
medication ranitidine?
A. Inhibiting proton pumps
B. Promoting the release of gastrin
C. Regenerating the gastric mucosa
D. Inhibiting the histamine at H 2 receptors Answer: D. Inhibiting the
histamine at H 2 receptors
◉ Which administration instruction would the nurse give a client
prescribed ranitidine 150 mg daily to treat peptic ulcer disease
(PUD)?
A. As needed
, B. With meals
C. At bedtime
D. Before meals Answer: C. At bedtime
◉ Which information would the nurse include when teaching a
client about the administration of ranitidine?
A. Ranitidine increases gastrointestinal peristalsis.
B. Ranitidine reduces gastric acidity in the stomach.
C. Ranitidine neutralizes the acid that is present in the stomach.
D. Ranitidine stops the production of hydrochloric acid in the
stomach. Answer: B. Ranitidine reduces gastric acidity in the
stomach.
◉ Which concern would prompt the nurse to contact the health care
provider when a client with gastric ulcers receives a prescription for
ranitidine 150 mg twice a day?
A. Ranitidine can increase the risk for gastrointestinal bleeding.
B. An administration route is not specified.
C. Ranitidine is contraindicated for gastric ulcers.
D. Ranitidine should be given with an adjuvant. Answer: B. An
administration route is not specified.
◉ Which medication is classified as an H 2 receptor antagonist?
Select all that apply. One, some, or all responses may be correct.
