NUR651 FINAL BRADLEY UNIVERSITY
Which of the types of chemical bonding between drugs and their receptors is the least
common? - Answers -Covalent
Which type of drug classification is most important to the practitioner? - Answers -
Therapeutic
Mechanism of Action - Answers -The manner in which molecular targets are affected
by the drug
Adverse Drug Reaction (ADR) can lead the patient to - Answers -stop taking the drug
Half-life is defined as - Answers -The time required for the plasma concentration of a
drug to be reduced by 50 percent
When one drug is more efficacious than another, it has... - Answers -A greater ability to
initiate a response
What is bioavailability? - Answers -The fraction of unchanged drug that reaches the
systemic circulation following administration by any route
Absorption is defined as: - Answers -The transfer of a drug from its site of
administration to the blood
How can Competitive antagonism be overcome? - Answers -by adding more agonist
How is children's dosing most often calculated? - Answers -MG/KG
A patient complains of pain from a migraine. How would the practitioner classify this
type of pain? - Answers -Central Neuropathic Pain
What stage of nociception is occurring when neurotransmitters in the dorsal horn
directly or indirectly depolarize the second-order neurons? - Answers -Trasmission
What are the four processes of Nociception - Answers -transduction, transmission,
modulation, and perception
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent or
intermittent?" What character of pain is the practitioner assessing? - Answers -
Temporal pattern
What is the maximum dose of acetaminophen in 24 hours? - Answers -4 grams
, Etodolac is in the same drug class as ibuprofen. What is its mechanism of action? -
Answers -It inhibits the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan) - Answers -opioid antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons) -
Answers -1. They are both metabolized by the same liver enzyme.
2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
3. The enzyme that metabolizes acetaminophen is induced by alcohol.
What is a contraindication of ibuprofen? - Answers -Ulcers
An adverse effect of opiates in elders is... - Answers -Bone fractures
Aspirin is different from the other NSAIDs because... - Answers -It binds irreversibly to
the COX enzyme
One of the properties that insulins are differentiated by is... - Answers -Duration of
action
Which form of insulin is the most bioavailable? - Answers -Humalog
What is the mechanism of action of sitagliptin (Januvia)? - Answers -Slows the
inactivation of incretin hormones by inhibiting dipeptidyl peptidase 4
How does canagliflozin (Invokana) control blood glucose levels? - Answers -By
reducing glucose reabsorption in the kidneys
What is the mechanism of action of Lantus? - Answers -Insulin precipitates into crystals
and is slowly absorbed over 24 hours
The most common complication of insulin therapy is... - Answers -Hypoglycemia
What is the mechanism of action of the sulfonylureas? - Answers -Increases insulin
secretion
What drug is the first-line therapy for type 2 diabetes? - Answers -Metformin
What are the primary symptoms of ketoacidosis? - Answers -Excessive thirst and
frequent urination
Type 2 diabetes is diagnosed when the A1C value is over: - Answers -6.5%
Description of Type 1 Diabetes - Answers -An autoimmune disorder that destroys the
beta cells in the pancreas
Which of the types of chemical bonding between drugs and their receptors is the least
common? - Answers -Covalent
Which type of drug classification is most important to the practitioner? - Answers -
Therapeutic
Mechanism of Action - Answers -The manner in which molecular targets are affected
by the drug
Adverse Drug Reaction (ADR) can lead the patient to - Answers -stop taking the drug
Half-life is defined as - Answers -The time required for the plasma concentration of a
drug to be reduced by 50 percent
When one drug is more efficacious than another, it has... - Answers -A greater ability to
initiate a response
What is bioavailability? - Answers -The fraction of unchanged drug that reaches the
systemic circulation following administration by any route
Absorption is defined as: - Answers -The transfer of a drug from its site of
administration to the blood
How can Competitive antagonism be overcome? - Answers -by adding more agonist
How is children's dosing most often calculated? - Answers -MG/KG
A patient complains of pain from a migraine. How would the practitioner classify this
type of pain? - Answers -Central Neuropathic Pain
What stage of nociception is occurring when neurotransmitters in the dorsal horn
directly or indirectly depolarize the second-order neurons? - Answers -Trasmission
What are the four processes of Nociception - Answers -transduction, transmission,
modulation, and perception
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent or
intermittent?" What character of pain is the practitioner assessing? - Answers -
Temporal pattern
What is the maximum dose of acetaminophen in 24 hours? - Answers -4 grams
, Etodolac is in the same drug class as ibuprofen. What is its mechanism of action? -
Answers -It inhibits the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan) - Answers -opioid antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons) -
Answers -1. They are both metabolized by the same liver enzyme.
2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
3. The enzyme that metabolizes acetaminophen is induced by alcohol.
What is a contraindication of ibuprofen? - Answers -Ulcers
An adverse effect of opiates in elders is... - Answers -Bone fractures
Aspirin is different from the other NSAIDs because... - Answers -It binds irreversibly to
the COX enzyme
One of the properties that insulins are differentiated by is... - Answers -Duration of
action
Which form of insulin is the most bioavailable? - Answers -Humalog
What is the mechanism of action of sitagliptin (Januvia)? - Answers -Slows the
inactivation of incretin hormones by inhibiting dipeptidyl peptidase 4
How does canagliflozin (Invokana) control blood glucose levels? - Answers -By
reducing glucose reabsorption in the kidneys
What is the mechanism of action of Lantus? - Answers -Insulin precipitates into crystals
and is slowly absorbed over 24 hours
The most common complication of insulin therapy is... - Answers -Hypoglycemia
What is the mechanism of action of the sulfonylureas? - Answers -Increases insulin
secretion
What drug is the first-line therapy for type 2 diabetes? - Answers -Metformin
What are the primary symptoms of ketoacidosis? - Answers -Excessive thirst and
frequent urination
Type 2 diabetes is diagnosed when the A1C value is over: - Answers -6.5%
Description of Type 1 Diabetes - Answers -An autoimmune disorder that destroys the
beta cells in the pancreas
