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Test Bank for Applied Pathophysiology: A Conceptual Approach, 4th Edition

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This complete test bank for Applied Pathophysiology: A Conceptual Approach, 4th Edition provides a comprehensive chapter guide covering chapters 1 through 18 with A+ verified correct answers. It is designed to support nursing and allied health students in understanding the underlying mechanisms of disease and their clinical implications. The test bank includes high-quality multiple-choice, true/false, short-answer, and application-based questions that emphasize critical thinking and concept-based learning. Core topics include cellular injury, inflammation, immunity, fluid and electrolyte imbalance, cardiovascular, respiratory, renal, endocrine, neurologic, gastrointestinal, and musculoskeletal pathophysiology. Each question is carefully aligned with textbook content and validated for accuracy, making this resource an essential study guide for exams, quizzes, and course assessments, as well as a reliable instructional tool for educators teaching applied pathophysiology courses.

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Uploaded on
January 12, 2026
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Written in
2025/2026
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Test Bank for Applied Pathophysiology:
A Conceptual Approach 4TH Edition
by Judi Nath, Carie Braun & Cindy
Anderson
Chapter Guide 1-18| A+ Verified Answers




1|P a g e

, Chapter 1: Introduction to Pathophysiology
1. The nucleus , which is essential for function and survival of the cell.

A) is the site of protein synthesis

B) contains the genetic code

C) transforms cellular energy

D) initiates aerobic metabolism



2. Although energy is not made in mitochondria, they are known as the power plants of the cell because
they:

A) contain RNA for protein synthesis.

B) utilize glycolysis for oxidative energy.

C) extract energy from organic compounds.

D) store calcium bonds for muscle contractions.



3. Although the basic structure of the cell plasma membrane is formed by a lipid bilayer, most of
the specific membrane functions are carried out by:

A) bound and transmembrane proteins.

B) complex, long carbohydrate chains.

C) surface antigens and hormone receptors.

D) a gating system of selective ion channels.



4. To effectively relay signals, cell-to-cell communication utilizes chemical messenger systems that:

A) displace surface receptor proteins.

B) accumulate within cell gap junctions.

C) bind to contractile microfilaments.

D) release secretions into extracellular fluid.



5. Aerobic metabolism, also known as oxidative metabolism, provides energy by:

A) removing the phosphate bonds from ATP.


2|P a g e

,B) combining hydrogen and oxygen to form water.

C) activating pyruvate stored in the cytoplasm.

D) breaking down glucose to form lactic acid.



6. Exocytosis, the reverse of endocytosis, is important in into the extracellular fluid.

A) Engulfing and ingesting fluid and proteins for transport

B) Killing, degrading, and dissolving harmful microorganisms

C) Removing cellular debris and releasing synthesized substances

D) Destruction of particles by lysosomal enzymes for secretion



7. The process responsible for generating and conducting membrane potentials is:

A) diffusion of current-carrying ions.

B) millivoltage of electrical potential.

C) polarization of charged particles.

D) ion channel neurotransmission.



8. Epithelial tissues are classified according to the shape of the cells and the number of layers. Which of
the following is a correctly matched description and type of epithelial tissue?

A) Simple epithelium: cells in contact with intercellular matrix; some do not extend to surface

B) Stratified epithelium: single layer of cells; all cells rest on basement membrane

C) Glandular epithelium: arise from surface epithelia and underlying connective tissue

D) Pseudostratified epithelium: multiple layers of cells; deepest layer rests on basement membrane



9. Connective tissue contains fibroblasts that are responsible for:

A) providing a fibrous framework for capillaries.

B) synthesis of collagen, elastin, and reticular fibers.

C) forming tendons and the fascia that covers muscles.

D) filling spaces between tissues to keep organs in place.




3|P a g e

, 10. Although all muscle tissue cells have some similarities, smooth muscle (also known as involuntary
muscle) differs by:

A) having dense bodies attached to actin filaments.

B) containing sarcomeres between Z lines and M bands.

C) having rapid contractions and abundant cross-striations.

D) contracting in response to increased intracellular calcium.



11. Which of the following aspects of the function of the nucleus is performed by ribosomal RNA
(rRNA)?

A) Copying and carrying DNA instructions for protein synthesis

B) Carrying amino acids to the site of protein synthesis

C) Providing the site where protein synthesis occurs

D) Regulating and controlling protein synthesis



12. Breakdown and removal of foreign substances and worn-out cell parts are performed by which of the
following organelles?

A) Lysosomes

B) Golgi apparatus

C) Ribosomes

D) Endoplasmic reticulum (ER)



13. Impairment in the function of peroxisomes would result in:

A) inadequate sites for protein synthesis.

B) an inability to transport cellular products across the cell membrane.

C) insufficient energy production within a cell.

D) accumulation of free radicals in the cytoplasm.




4|P a g e
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