Test Bank for Berne and Levy Physiology, 8th Edition

Berne and Levy Physiology 8th Edition
Koepp

, Berne and Levy Physiology 8th Edition
Koepp



Berne and Levy Physiology 8th Edition KoeppenTest Bank Koeppen: Bern

e and Levy Physiology, 8th Edition

Chapter 01: Principles of Cell Function
Test Bank
Multiple Choice

1. The subcellular structure that degrades proteins is called the:

A. Tight junction
B. Mitochondria
C. Lysosome
D. Plasma membrane
E. Ribosome
ANS: C

2. An experiment is done to measure the uptake of an amino acid into a cell. The
foll owing data are obtained:


N




If Na+ is removed from the extracellular bathing solution, or if a drug is added that
preve nts the cell from making adenosine triphosphate (ATP), the uptake of amino
acid into th e cell is markedly reduced. According to this information, which of the
followingmechan isms is probably responsible for the transport of the amino acid into
the cell?

A. Passive diffusion through the lipid bilayer
B. Uniporter
C. Transport ATPase
D. Na+ symporter
E. Na+ antiporter
ANS: D

3. A membrane permeable by only Na+ separates two compartments contain
ing Na2SO4,shown as follows:

, Berne and Levy Physiology 8th Edition
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Electrodes are placed in both compartments, and a voltage is applied (that of
compartme nt A is held at 0 mV). What voltage applied to compartment B would
resultin no net mo vement of Na+ across the membrane separating the compartments?

A. –60 mV
B. –30 mV
C. 0 mV
D. +30 mV
E.
+60 m
V ANS: E

4. The resting membrane potentN
TV ial oRf a Ic e llGis –
B.C
85 m V. The intracellular and U S N concentrations of several ions are indicat
extracellular
ed in the following table, as is the calculated
Nernst equilibrium potential (Ei) for each of these ions:

Ion Concentration Concentration Ei
Inside Cell Outside Cell
Na+ 12 mEq/L 145 mEq/L 66 mV
K+ 150 mEq/L 4 mEq/L –96 mV
Cl– 30 mEq/L 105 mEq/L –33 mV
Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV

The membrane has channels for Na+, K+, Cl–
, and Ca++. The conductance of the membrane is the greatest for which ion
?

A. Na+
B. K+
C. Cl–
D. Ca++
ANS:
B

5. A cell contains the following membrane transporters:




Na+ channelK+ channe

, Berne and Levy Physiology 8th Edition
l Na+,K+-ATPase
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The resting membrane voltage of the cell is –80 mV, and the intracellular and
extracellular ion concentrations are as follows:

Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L 145 mEq/L
K+ 120 mEq/L 4 mEq/L

The cell is treated with a drug to inhibit the Na+,K+-
ATPase. What would be the effect ofthis drug on the following parameters?

Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize

ANS: B

6. Which of the labeled proteins (shaded) is attached to the membrane
by a glycosylphosphatidylinositol (GPI) anchor?




ANS: E


7.
A cell has channels for Na+, K+, and Cl–
in its plasma membrane. The resting membrane potential is –
60 mV (cell interior negative). The intracellular and extracellular
concentrations for these ions, as well as the calculated Nernst potentials,
are listed as follows: