//.stuvia.////doc///2026//2027.100%A+.
Phase 1
Sunday, December 10, 2023 3:59 PM
1a. CPE Schedule Table
CPE Schedule Table
Phase 1 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
1a. CPE schedule table 12/3/23 00:45
1b. Feedback and Synthesis Improvement 12/3/23 02:00
Plan
1c. Three screenshots of GoReact and 12/17/23 01:00
reflective summary
Phase 2 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
2a. Review CPE schedule table for your 12/10/23 00:15
progress
2b. Feedback and Synthesis Improvement 12/11/23 03:00
Plan
2b. Patient or Healthcare Focused 12/11/23 03:00
Consumer-Focused Synthesis
2c. Three screenshots of GoReact and 12/17/23 01:00
reflective summary
Phase 3 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
3a. Review CPE schedule table for your 12/18/23 00:15
progress
3b. Feedback and Synthesis Improvement 12/18/23 03:00
Plan
3b. Preceptor or colleague focused 12/19/23 03:00
synthesis
3c. Feedback and Synthesis Improvement 12/20/23 02:00
Treatment Plan
3c. Patient or Healthcare Consumer- 12/20/23 02:00
Focused Treatment Plan
3d. Three screenshots of GoReact and 1/2/24 01:00
reflective summary
1b. Feedback and Synthesis Improvement Plan
Alzheimer's disease, recognized as the most predominant form of dementia, unfolds as a progressive
neurodegenerative disorder. Characterized by progressive neurologic deterioration leading to brain atrophy
and neuronal death, Alzheimer's disease manifests through the formation of plaques and tangles within the
cerebral structures (Mayo Clinic, 2022). As an irreversible and debilitating neurodegenerative disorder,
Alzheimer's disease affects approximately 5.8 million individuals aged 65 and above in the United States,
posing a significant public health challenge (Alzheimer's Association, 2022). Despite ongoing research, the
exact pathophysiological manifestations of Alzheimer's remain in question. Suspected contributions from
various factors such as genetics, environmental influences, and lifestyle choices, result in diverse disease
1
D027 Advanced Pathopharmacological Foundations Page 1
, //.stuvia.////doc///2026//2027.100%A+.
various factors such as genetics, environmental influences, and lifestyle choices, result in diverse disease
activation patterns among some individuals (Sheppard & Coleman, 2020).
Clinical progression unfolds through stages, with an early phase believed to begin up to a decade before
observable memory or cognitive decline. Recognition often occurs as the stages transition from mild to
moderate. The mild stage is characterized by disruptive memory loss affecting daily tasks, wandering, and
misplacement of items, prompting diagnosis as individuals and their surroundings recognize deviations from
normalcy (National Institute of Health, 2020). Advancing to the moderate stage involves escalating memory
loss, withdrawal from social activities, language difficulties, and challenges in reading and writing.
Pronounced restlessness and agitation become characteristic during this phase (CDC, n.d.). The severe stage
marks an advanced state where individuals lose the ability to communicate, rely on others for care, and
experience prominent physical manifestations such as difficulty swallowing, seizures, and weight loss.
Diagnosing Alzheimer's disease necessitates a comprehensive approach, including an assessment of overall
health and patient history. Clinical tests, such as CT, MRI, or PET scans, aid in supporting a diagnosis and
excluding alternative causes of symptoms. Additional diagnostic measures encompass urine and blood
samples, memory tests, counting tests, and language tests to identify potential alternative causes. A full
psychological evaluation may also be ordered to rule out potential mental health conditions contributing to
observed symptoms. The disease's hallmark features, plaques, and tangles, disrupt cellular communication
and neuronal support, leading to interference with critical brain functions in the moderate stages.
Cholinesterase inhibitors and lifestyle modifications present potential strategies to impede the degenerative
process and slow the disease's progression (National Institute on Aging, n.d.). The complexity of Alzheimer's
disease demands a multidisciplinary approach to understanding, diagnosis, and effective management,
emphasizing the ongoing need for research to uncover its intricate mechanisms and develop innovative
therapeutic strategies.
Peer Feedback:
Recognizing that a thorough synthesis of Alzheimer's could span multiple pages, I am glad that the chosen
data effectively conveys the essential aspects within the given limitations. Your insights into the challenges of
presenting such extensive information concisely are valuable. I can’t emphasize enough the need for focus
and clarity, this will align with your goal of elevating your writing to an advanced level. The quest for
precision can sometimes lead to wordiness and confusion, so clarity is beneficial. While more in-depth
feedback could have been beneficial, the brevity of the synthesis limited the opportunity for extensive
commentary.
As you pursue your aspirations as a Master's prepared nurse, refining the balance between depth and
conciseness in your writing will be an ongoing process. Given the constraints of synthesizing information
within a one-page limit, you succeeded in balancing the various aspects of Alzheimer's disease within these
confined guidelines. Your awareness of this challenge led you to write an effective synthesis and will prove
instrumental in fostering success in your future assignments.
References:
Alzheimer's Association. (2022). Why Get Checked?
https://www.alz.org/alzheimers-dementia/diagnosis/why-get-checked
Sheppard, O., & Coleman, M. P. (2020). Alzheimer’s Disease: etiology, neuropathology and
pathogenesis. https://doi.org/10.36255/exonpublications.alzheimersdisease.2020.ch1
National Institute on Aging. (n.d.). What are the signs of Alzheimer’s disease?
https://www.nia.nih.gov/health/what-are-signs-alzheimers-disease
National Institute of Health. (2020). A combination of healthy lifestyle traits may
substantially reduce Alzheimer's. https://www.nih.gov/news-events/news-releases/combination-healthy-
2
D027 Advanced Pathopharmacological Foundations Page 2
Phase 1
Sunday, December 10, 2023 3:59 PM
1a. CPE Schedule Table
CPE Schedule Table
Phase 1 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
1a. CPE schedule table 12/3/23 00:45
1b. Feedback and Synthesis Improvement 12/3/23 02:00
Plan
1c. Three screenshots of GoReact and 12/17/23 01:00
reflective summary
Phase 2 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
2a. Review CPE schedule table for your 12/10/23 00:15
progress
2b. Feedback and Synthesis Improvement 12/11/23 03:00
Plan
2b. Patient or Healthcare Focused 12/11/23 03:00
Consumer-Focused Synthesis
2c. Three screenshots of GoReact and 12/17/23 01:00
reflective summary
Phase 3 Proposed Date of Estimated Time to Complete
Completion (Hours/Minutes)
3a. Review CPE schedule table for your 12/18/23 00:15
progress
3b. Feedback and Synthesis Improvement 12/18/23 03:00
Plan
3b. Preceptor or colleague focused 12/19/23 03:00
synthesis
3c. Feedback and Synthesis Improvement 12/20/23 02:00
Treatment Plan
3c. Patient or Healthcare Consumer- 12/20/23 02:00
Focused Treatment Plan
3d. Three screenshots of GoReact and 1/2/24 01:00
reflective summary
1b. Feedback and Synthesis Improvement Plan
Alzheimer's disease, recognized as the most predominant form of dementia, unfolds as a progressive
neurodegenerative disorder. Characterized by progressive neurologic deterioration leading to brain atrophy
and neuronal death, Alzheimer's disease manifests through the formation of plaques and tangles within the
cerebral structures (Mayo Clinic, 2022). As an irreversible and debilitating neurodegenerative disorder,
Alzheimer's disease affects approximately 5.8 million individuals aged 65 and above in the United States,
posing a significant public health challenge (Alzheimer's Association, 2022). Despite ongoing research, the
exact pathophysiological manifestations of Alzheimer's remain in question. Suspected contributions from
various factors such as genetics, environmental influences, and lifestyle choices, result in diverse disease
1
D027 Advanced Pathopharmacological Foundations Page 1
, //.stuvia.////doc///2026//2027.100%A+.
various factors such as genetics, environmental influences, and lifestyle choices, result in diverse disease
activation patterns among some individuals (Sheppard & Coleman, 2020).
Clinical progression unfolds through stages, with an early phase believed to begin up to a decade before
observable memory or cognitive decline. Recognition often occurs as the stages transition from mild to
moderate. The mild stage is characterized by disruptive memory loss affecting daily tasks, wandering, and
misplacement of items, prompting diagnosis as individuals and their surroundings recognize deviations from
normalcy (National Institute of Health, 2020). Advancing to the moderate stage involves escalating memory
loss, withdrawal from social activities, language difficulties, and challenges in reading and writing.
Pronounced restlessness and agitation become characteristic during this phase (CDC, n.d.). The severe stage
marks an advanced state where individuals lose the ability to communicate, rely on others for care, and
experience prominent physical manifestations such as difficulty swallowing, seizures, and weight loss.
Diagnosing Alzheimer's disease necessitates a comprehensive approach, including an assessment of overall
health and patient history. Clinical tests, such as CT, MRI, or PET scans, aid in supporting a diagnosis and
excluding alternative causes of symptoms. Additional diagnostic measures encompass urine and blood
samples, memory tests, counting tests, and language tests to identify potential alternative causes. A full
psychological evaluation may also be ordered to rule out potential mental health conditions contributing to
observed symptoms. The disease's hallmark features, plaques, and tangles, disrupt cellular communication
and neuronal support, leading to interference with critical brain functions in the moderate stages.
Cholinesterase inhibitors and lifestyle modifications present potential strategies to impede the degenerative
process and slow the disease's progression (National Institute on Aging, n.d.). The complexity of Alzheimer's
disease demands a multidisciplinary approach to understanding, diagnosis, and effective management,
emphasizing the ongoing need for research to uncover its intricate mechanisms and develop innovative
therapeutic strategies.
Peer Feedback:
Recognizing that a thorough synthesis of Alzheimer's could span multiple pages, I am glad that the chosen
data effectively conveys the essential aspects within the given limitations. Your insights into the challenges of
presenting such extensive information concisely are valuable. I can’t emphasize enough the need for focus
and clarity, this will align with your goal of elevating your writing to an advanced level. The quest for
precision can sometimes lead to wordiness and confusion, so clarity is beneficial. While more in-depth
feedback could have been beneficial, the brevity of the synthesis limited the opportunity for extensive
commentary.
As you pursue your aspirations as a Master's prepared nurse, refining the balance between depth and
conciseness in your writing will be an ongoing process. Given the constraints of synthesizing information
within a one-page limit, you succeeded in balancing the various aspects of Alzheimer's disease within these
confined guidelines. Your awareness of this challenge led you to write an effective synthesis and will prove
instrumental in fostering success in your future assignments.
References:
Alzheimer's Association. (2022). Why Get Checked?
https://www.alz.org/alzheimers-dementia/diagnosis/why-get-checked
Sheppard, O., & Coleman, M. P. (2020). Alzheimer’s Disease: etiology, neuropathology and
pathogenesis. https://doi.org/10.36255/exonpublications.alzheimersdisease.2020.ch1
National Institute on Aging. (n.d.). What are the signs of Alzheimer’s disease?
https://www.nia.nih.gov/health/what-are-signs-alzheimers-disease
National Institute of Health. (2020). A combination of healthy lifestyle traits may
substantially reduce Alzheimer's. https://www.nih.gov/news-events/news-releases/combination-healthy-
2
D027 Advanced Pathopharmacological Foundations Page 2
