GUARANTEE A+
✔✔Secreted proteins - ✔✔Destined to leave the cell
✔✔What is the smooth endoplasmic reticulum responsible for? - ✔✔Fat processing
✔✔Characteristics of the mitochondira - ✔✔It is ATP. Is double layered, and is passed
down from the mom only
✔✔What is the lysosome similar to? - ✔✔A garbage disposal
✔✔Characteristics of long transport - ✔✔Polymer: microtubules. Monomer: tubulin.
Motor protein (vesicle transporting ATPase): kinesin is positive directed and dynein is
negative directed
✔✔Characteristics of local transport - ✔✔Polymer: filamentous actin. Monomer: globular
actin. Motor protein (vesicle transporting ATPase): mysoin.
✔✔Central Dogma - ✔✔DNA ---replication---> DNA ---transcription---> RNA ---
translation---> protein
✔✔What part of the central dogma occurs in the nucleus? - ✔✔Replication and
Transcription
✔✔What part of the central dogma occurs in the cytoplasm? - ✔✔Translation
✔✔What part of the central dogma is semi-conservative? - ✔✔Replication
✔✔What does semi-conservative mean? - ✔✔When creating more DNA we don't
destroy the original two strands, rather we keep them.
✔✔Helicases - ✔✔Unwinds the DNA, and breaks hydrogen bonds
✔✔Characteristics of DNA polymerase - ✔✔Reads 3' to 5'. Adds 5' to 3'. Has
phosphodiester bonds.
✔✔What is RNA synthesized from? - ✔✔DNA
✔✔What are the DNA bases? - ✔✔A, T, G, C
✔✔What are the RNA bases? - ✔✔A, U, G, C
✔✔What is the promoter in DNA - ✔✔TATA box
, ✔✔Characteristics of RNA polymerase - ✔✔3' to 5'. Breaks hydrogen bonds between
DNA strands. Add appropriate bases, and results in phosphodiester bonds between
ribose sugars.
✔✔Splicing - ✔✔Removal of introns and joining of exons
✔✔Introns - ✔✔These stay in the nucleus
✔✔Exons - ✔✔These exit the nucleus and are expressed
✔✔What are codons? - ✔✔3 bases on mRNA
✔✔What is the start codon? - ✔✔AUG
✔✔What does the stop codon do? - ✔✔Stops translation
✔✔Characteristics of the ribosome - ✔✔5' to 3'. Links amino acids via peptide bonds
✔✔tRNA - ✔✔Transfer RNA. Has the anti-codon and carries amino acids to the
ribosomes.
✔✔Signal Recognition Particle - ✔✔(SRP). Stops translation and moves the rough ER
✔✔SRP receptor characteristics - ✔✔Located on the rough ER membrane and binds to
SRP to help guide ribosomes to protein translocater (translocon)
✔✔Characteristics of translocon - ✔✔Transmembrane protein (on rough ER), aid
proteins entering the lumen of the ER (to integrate proteins into ER membrane)
✔✔If there is a signal peptide where does it go? - ✔✔Lysosome
✔✔If there is no signal peptide where does it go? - ✔✔Cytoplasm
✔✔rRNA - ✔✔Ribosomal RNA
✔✔mRNA - ✔✔Messenger RNA. Convey genetic info from DNA to ribosomes.
✔✔What are the four types of tissue? - ✔✔Epithelial, Connective, Muscle, and Nervous
✔✔Characteristics of Epithelial Cells - ✔✔Form layers. Has polarity orientation (apical
vs. basilar). Avascular (contains no blood). Reproduce themselves.