1|Page
TEST BANK FOR PMHNP BOARDS EXAMS NEWEST 2025/2026
ACTUAL EXAM WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (100% VERIFIED ANSWERS) |ALREADY
GRADED A+| ||PROFESSOR VERIFIED||
Which antidepressants increase does not increase DA or 5-HT
but increases NE? - ANSWER-Desipramine
Which antidepressants increase NE and 5-HT, but not DA -
ANSWER-Amitriptyline
Duloxetine
Effexor
Which antidepressants increase NE, 5HT and DA - ANSWER-
Phenelzine
Selegiline
_____ of every _____ black or white persons may have an
exaggerated response to beta-blockers due to a polymorphism in
CYP450 enzymes - ANSWER-1
15
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Sialorrhea - ANSWER-excessive salivation
Sialorrhea is associated with side effects of - ANSWER-Clozapine
(31-48%)
Clozapine has a boxed warning concerning - ANSWER-
AGRANULOCYTOSIS (severe neutropenia is associated with
significant risk of serious infection or death)
orthostatic hypotension
bradycardia
syncope
(more likely to occur during initiation of tx and titration of dose)
Baseline ANC must be at least ___________ before initiation of
Clozapine tx - ANSWER-1500
,3|Page
Due to _________ clozapine is available only under a Risk
Evaluation Mitigation Strategy (REMS) program. - ANSWER-risk
of severe neutropenia (ANC<500)
Acute alcohol ingestion _______ the rate of drug metabolism -
ANSWER-lowers (inhibits)
Acute alcohol ingestion causes benzodiazepine level to -
ANSWER-increase
Hypnotic drug of choice for pt with insomnia who wants to take it
in the middle of the night without causing significant grogginess in
the morning - ANSWER-Zalepon
Half life of Zalepon - ANSWER-1-2 hours
What is the mechanism of action of galantamine? - ANSWER-
competitive inhibitor of acetylcholinesterase
, 4|Page
According to the Lilly Worldwide Pharmacovigilance Safety
Database, what is the rate of spontaneous abortion in olanzapine
exposed pregnancy? - ANSWER-13% (falls within range of
normal historic control rates)
Exposure during gestation to this medication can cause
arrhythmias, polyhydramnios, nephrogenic diabetes insidious,
and "floppy infant syndrome" - ANSWER-LIthium
Desvenlafaxine is ________ protein bound with ____ likelihood of
displacing tightly protein-bound medication like phenytoin and
warfarin - ANSWER-weakly
reduced
The SNRIs have an ______ onset of action compared to SSRIs
due to _________ - ANSWER-earlier
rapid down-regulation of beta-adrenergic receptor-coupled cAMP
Do stimulants cause an increase in tics - ANSWER-no (can
worsen for a short interval, then go back to baseline)
TEST BANK FOR PMHNP BOARDS EXAMS NEWEST 2025/2026
ACTUAL EXAM WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (100% VERIFIED ANSWERS) |ALREADY
GRADED A+| ||PROFESSOR VERIFIED||
Which antidepressants increase does not increase DA or 5-HT
but increases NE? - ANSWER-Desipramine
Which antidepressants increase NE and 5-HT, but not DA -
ANSWER-Amitriptyline
Duloxetine
Effexor
Which antidepressants increase NE, 5HT and DA - ANSWER-
Phenelzine
Selegiline
_____ of every _____ black or white persons may have an
exaggerated response to beta-blockers due to a polymorphism in
CYP450 enzymes - ANSWER-1
15
,2|Page
Sialorrhea - ANSWER-excessive salivation
Sialorrhea is associated with side effects of - ANSWER-Clozapine
(31-48%)
Clozapine has a boxed warning concerning - ANSWER-
AGRANULOCYTOSIS (severe neutropenia is associated with
significant risk of serious infection or death)
orthostatic hypotension
bradycardia
syncope
(more likely to occur during initiation of tx and titration of dose)
Baseline ANC must be at least ___________ before initiation of
Clozapine tx - ANSWER-1500
,3|Page
Due to _________ clozapine is available only under a Risk
Evaluation Mitigation Strategy (REMS) program. - ANSWER-risk
of severe neutropenia (ANC<500)
Acute alcohol ingestion _______ the rate of drug metabolism -
ANSWER-lowers (inhibits)
Acute alcohol ingestion causes benzodiazepine level to -
ANSWER-increase
Hypnotic drug of choice for pt with insomnia who wants to take it
in the middle of the night without causing significant grogginess in
the morning - ANSWER-Zalepon
Half life of Zalepon - ANSWER-1-2 hours
What is the mechanism of action of galantamine? - ANSWER-
competitive inhibitor of acetylcholinesterase
, 4|Page
According to the Lilly Worldwide Pharmacovigilance Safety
Database, what is the rate of spontaneous abortion in olanzapine
exposed pregnancy? - ANSWER-13% (falls within range of
normal historic control rates)
Exposure during gestation to this medication can cause
arrhythmias, polyhydramnios, nephrogenic diabetes insidious,
and "floppy infant syndrome" - ANSWER-LIthium
Desvenlafaxine is ________ protein bound with ____ likelihood of
displacing tightly protein-bound medication like phenytoin and
warfarin - ANSWER-weakly
reduced
The SNRIs have an ______ onset of action compared to SSRIs
due to _________ - ANSWER-earlier
rapid down-regulation of beta-adrenergic receptor-coupled cAMP
Do stimulants cause an increase in tics - ANSWER-no (can
worsen for a short interval, then go back to baseline)
