NSCI 175 EXAM 1 REVIEW QUESTIONS
The part of the neuron that is myelinated - Answer -axon
This 1800s scientist believed that neurons were continuous - Answer -Golgi (reticular
theory)
A glial that myelinates neurons in the PNS - Answer -Schwann cells
A neuroscientist that finds new similarities in function between differing types of neurons
would be performing which level of analysis? - Answer -cellular neuroscience
The technique that assesses gene expression by measuring mRNA levels - Answer -in
situ hybridization (ISH)
This structure on the neuronal membrane moves 2 K+ ions inside the cell and 3 Na+
outside of the cell - Answer -sodium potassium pump
This equation uses extra and intracellular concentrations of one ion - Answer -Nernst
equation
This equation is used to calculate resting membrane potential - Answer -Goldman
equation
Suppose the concentration of K+ inside the neuron is 100mM and 10mM outside the
neuron. The concentration of Na+ inside the cell is 0mM and outside the cell is 100mM
outside. If the membrane is 10 times more permeable to K+ than Na+, what is the
resting membrane potential of the neuron? - Answer -Vm = 61.5 (PK+ x K+out + PNa x
Naout)/(PK x Kin + PNa X Na+ in)
= 61.5 log (10 x 10 + 100)/(10 x 100 + 0)
= 61.5 log (200/1000)
= 61.5 log (0.2)
= -43.1 mV
Typically, the K+ concentration outside the cell is 5 nM, and the concentration inside the
cell is 100nM. If the concentration of the K+ outside of the cell were to increase to 20nM
and all other constants remained the same, what would happen to the equilibrium
potential of K+? - Answer -EK+ would become more positive
The hyperpolarization phase of the action potential is due to what? - Answer -
Prolonged opening of the voltage-gated K+ Channels
This is the phase of action potential firing where voltage-gated sodium channels open -
Answer -Stage 3 (rising phase)
The part of the neuron that is myelinated - Answer -axon
This 1800s scientist believed that neurons were continuous - Answer -Golgi (reticular
theory)
A glial that myelinates neurons in the PNS - Answer -Schwann cells
A neuroscientist that finds new similarities in function between differing types of neurons
would be performing which level of analysis? - Answer -cellular neuroscience
The technique that assesses gene expression by measuring mRNA levels - Answer -in
situ hybridization (ISH)
This structure on the neuronal membrane moves 2 K+ ions inside the cell and 3 Na+
outside of the cell - Answer -sodium potassium pump
This equation uses extra and intracellular concentrations of one ion - Answer -Nernst
equation
This equation is used to calculate resting membrane potential - Answer -Goldman
equation
Suppose the concentration of K+ inside the neuron is 100mM and 10mM outside the
neuron. The concentration of Na+ inside the cell is 0mM and outside the cell is 100mM
outside. If the membrane is 10 times more permeable to K+ than Na+, what is the
resting membrane potential of the neuron? - Answer -Vm = 61.5 (PK+ x K+out + PNa x
Naout)/(PK x Kin + PNa X Na+ in)
= 61.5 log (10 x 10 + 100)/(10 x 100 + 0)
= 61.5 log (200/1000)
= 61.5 log (0.2)
= -43.1 mV
Typically, the K+ concentration outside the cell is 5 nM, and the concentration inside the
cell is 100nM. If the concentration of the K+ outside of the cell were to increase to 20nM
and all other constants remained the same, what would happen to the equilibrium
potential of K+? - Answer -EK+ would become more positive
The hyperpolarization phase of the action potential is due to what? - Answer -
Prolonged opening of the voltage-gated K+ Channels
This is the phase of action potential firing where voltage-gated sodium channels open -
Answer -Stage 3 (rising phase)
