DDS EXAM 3 QUESTIONS AND ANSWERS
______________ dosage forms are products of semisolid consistency and are applied to the
skin/mucous membranes for therapeutic action or cosmetic purposes. - CORRECT
ANSWER✅✅semisolid
Which of the following is a type of semisolid dosage form?
a) Ointment
b) Creams
c) Pastes
d) Gels
e) All of the above - CORRECT ANSWER✅✅E
T/F: A semisolid should be smooth, hydrating, non-gritty, non-greasy, non-staining, and non-hygroscopic
in nature. - CORRECT ANSWER✅✅True
Which of the following is NOT a therapeutic considerationdesirable in semisolids?
a) Non-irritating
b) Low sensitization
c) Readily miscible with skin secretions
d) Alters the membrane of the skin
e) All of the above - CORRECT ANSWER✅✅D
Which of the following is NOT an advantage of semisolids?
a) Avoids first pass metabolism
b) Application with finger may cause contamination
c) More stable than liquid dosage form
,d) Site specific action
e) Suitable dosage form for bitter drugs or patient having difficulty with oral administration - CORRECT
ANSWER✅✅B
Which of the following is a disadvantage of semisolids?
a) May cause staining
b) May cause irritation/allergic reaction
c) Bulky to handle
d) All of the above
e) None of the above - CORRECT ANSWER✅✅D
Which of the following semisolid dosage forms is a soft hydrocarbon-based semisolid preparation with
drug or active ingredient meshed in a matrix of solid hydrocarbon base?
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅A
___________ are a viscous, semisolid emulsion system with opaque appearance whose
texture/consistency depends on formulation with w/o or o/w systems being used.
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅B
Ointments with a higher percentage of insoluble solid is referred to as a ___________. Their textures are
stiff due to a high amount of particulate matter.
,a) Poultice
b) Cream
c) Paste
d) Gel - CORRECT ANSWER✅✅C
Which of the following is a semisolid coherent system with a liquid phase constrained in a polymeric
matrix and whose texture is smooth, transparent, translucent, and non-greasy?
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅D
Which of the following is a function of the skin?
a) Temperature regulation
b) Vitamin D synthesis
c) Excretion
d) Protection
e) All of the above - CORRECT ANSWER✅✅E
T/F: The skin is the largest organ. - CORRECT ANSWER✅✅True
T/F: The skin is 0.5mm thick and does not vary among different regions of the body. - CORRECT
ANSWER✅✅False
T/F: Although the skin is one of the major sites for non-invasive delivery of therapeutic agents, this task
can be relatively challenging owing to the impermeability of the skin. - CORRECT ANSWER✅✅True
, The epidermis has two layers significant to transdermal drug delivery: the __________ __________,
which is 10-20 uM thick, has 20 rows of flat layers of cells, and is constantly shed and renewed; and the
_________ _________, which has multiple layers, enzymes, nerve endings, but no blood vessels. -
CORRECT ANSWER✅✅stratum corneum; viable epidermis
______________ absorption involves the passive diffusion of substance through the skin - CORRECT
ANSWER✅✅percutaneous
Which of the following includes intracellular penetration and intercellular penetration?
a) Transepidermal
b) Transappendageal - CORRECT ANSWER✅✅A
Which of the following types of penetration is through the sweat gland?
a) Transepidermal
b) Transappendageal - CORRECT ANSWER✅✅B
Which of the following types of diffusion would be utilized by hydrophobic drugs?
a) Transcellular
b) Paracellular - CORRECT ANSWER✅✅A
Which of the following types of diffusion would be utilized by hydrophilic drugs?
a) Transcellular
b) Paracellular - CORRECT ANSWER✅✅B
Which of the following is a factor influencing penetration of the skin?
______________ dosage forms are products of semisolid consistency and are applied to the
skin/mucous membranes for therapeutic action or cosmetic purposes. - CORRECT
ANSWER✅✅semisolid
Which of the following is a type of semisolid dosage form?
a) Ointment
b) Creams
c) Pastes
d) Gels
e) All of the above - CORRECT ANSWER✅✅E
T/F: A semisolid should be smooth, hydrating, non-gritty, non-greasy, non-staining, and non-hygroscopic
in nature. - CORRECT ANSWER✅✅True
Which of the following is NOT a therapeutic considerationdesirable in semisolids?
a) Non-irritating
b) Low sensitization
c) Readily miscible with skin secretions
d) Alters the membrane of the skin
e) All of the above - CORRECT ANSWER✅✅D
Which of the following is NOT an advantage of semisolids?
a) Avoids first pass metabolism
b) Application with finger may cause contamination
c) More stable than liquid dosage form
,d) Site specific action
e) Suitable dosage form for bitter drugs or patient having difficulty with oral administration - CORRECT
ANSWER✅✅B
Which of the following is a disadvantage of semisolids?
a) May cause staining
b) May cause irritation/allergic reaction
c) Bulky to handle
d) All of the above
e) None of the above - CORRECT ANSWER✅✅D
Which of the following semisolid dosage forms is a soft hydrocarbon-based semisolid preparation with
drug or active ingredient meshed in a matrix of solid hydrocarbon base?
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅A
___________ are a viscous, semisolid emulsion system with opaque appearance whose
texture/consistency depends on formulation with w/o or o/w systems being used.
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅B
Ointments with a higher percentage of insoluble solid is referred to as a ___________. Their textures are
stiff due to a high amount of particulate matter.
,a) Poultice
b) Cream
c) Paste
d) Gel - CORRECT ANSWER✅✅C
Which of the following is a semisolid coherent system with a liquid phase constrained in a polymeric
matrix and whose texture is smooth, transparent, translucent, and non-greasy?
a) Ointment
b) Creams
c) Pastes
d) Gels - CORRECT ANSWER✅✅D
Which of the following is a function of the skin?
a) Temperature regulation
b) Vitamin D synthesis
c) Excretion
d) Protection
e) All of the above - CORRECT ANSWER✅✅E
T/F: The skin is the largest organ. - CORRECT ANSWER✅✅True
T/F: The skin is 0.5mm thick and does not vary among different regions of the body. - CORRECT
ANSWER✅✅False
T/F: Although the skin is one of the major sites for non-invasive delivery of therapeutic agents, this task
can be relatively challenging owing to the impermeability of the skin. - CORRECT ANSWER✅✅True
, The epidermis has two layers significant to transdermal drug delivery: the __________ __________,
which is 10-20 uM thick, has 20 rows of flat layers of cells, and is constantly shed and renewed; and the
_________ _________, which has multiple layers, enzymes, nerve endings, but no blood vessels. -
CORRECT ANSWER✅✅stratum corneum; viable epidermis
______________ absorption involves the passive diffusion of substance through the skin - CORRECT
ANSWER✅✅percutaneous
Which of the following includes intracellular penetration and intercellular penetration?
a) Transepidermal
b) Transappendageal - CORRECT ANSWER✅✅A
Which of the following types of penetration is through the sweat gland?
a) Transepidermal
b) Transappendageal - CORRECT ANSWER✅✅B
Which of the following types of diffusion would be utilized by hydrophobic drugs?
a) Transcellular
b) Paracellular - CORRECT ANSWER✅✅A
Which of the following types of diffusion would be utilized by hydrophilic drugs?
a) Transcellular
b) Paracellular - CORRECT ANSWER✅✅B
Which of the following is a factor influencing penetration of the skin?
