NSG5003 PHARM PRACTICE QUESTIONS EXAM 1
SOUTH UNIVERSITY ( REAL EXAM INSIGHT)
GUARANTEED PASS A QUESTION AND ANSWERS
Which of the following enzymes, released from dying cells, may
indicate problems in the liver?
a. alanine aminotransferase
b. aspartate aminotransferase c. alkaline phosphatase
d. all of the above
e. none of the above
D
Researchers hypothesize that the disappearance of dopamine-
generating cells in the midbrain in Parkinson's Disease may be
related to oxidative stress due to a decrease in the amount of
glutathione in the midbrain. The best explanation for this theory
is which of the following?
a. DNA synthesis requires glutathione for optimal development.
b. Dopamine synthesis requires glutathione to prevent free
radical production.
,c. Free radicals produced via dopamine synthesis are neutralized
by glutathione.
d. Glutathione is needed for entry of dopamine into the cerebral
circulation.
C
Which of the following is(are) true regarding aging?
a. may involve an increase in autoantibodies
b. may result from damage accumulation
c. both are true
d. neither is true
C
In theories of aging, cross-linking implies which of the following?
a. The lifespan and number of times a cell can replicate are
preprogrammed.
b. The number of cell doublings is limited.
c. There is oxygen toxicity.
d. Cell permeability decreases.
,D
Mr. Forbes is being prepared for open heart surgery when he
suffers a myocardial infarction in which a large part of his left
ventricle has suffered lethal cell injury.
Mr. Forbes' CPK-MB and LDH1, enzymes associated with
myocardial cells, are significantly elevated. What is the best
explanation for this?
a. It is a sign that necrotic myocardial cells have released their
cytoplasmic contents into the blood.
b. It is a sign of reversible fatty accumulation in the myocardial
cells
c. It is a sign that the myocardial cells are undergoing
hypertrophy.
d. None of the above.
A
If a tissue specimen of myocardial cells were obtained for
examination from Mr. Forbes, which of the following findings
would indicate irreversible cell injury?
a. cellular swelling
b. decreased ATP production
, c. decreased intracellular calcium
d. dissolution of nuclear material
D
The accumulation of lactic acid that occurs with impaired energy
production results from which of the following?
a. increased intracellular glucose
b. increased anaerobic metabolism
c. decreased metabolic rate
d. increased oxidative phosphorylation
B
A mountain climber is stranded at 23,000 feet in the Swiss Alps
and has lost all his equipment and supplies in an avalanche.
Subsequently, he suffers cell injury due to impaired ATP
production. The reason for the decrease in ATP is which of the
following?
a. enzyme inhibition
b. uncoupling
c. hypoxia
SOUTH UNIVERSITY ( REAL EXAM INSIGHT)
GUARANTEED PASS A QUESTION AND ANSWERS
Which of the following enzymes, released from dying cells, may
indicate problems in the liver?
a. alanine aminotransferase
b. aspartate aminotransferase c. alkaline phosphatase
d. all of the above
e. none of the above
D
Researchers hypothesize that the disappearance of dopamine-
generating cells in the midbrain in Parkinson's Disease may be
related to oxidative stress due to a decrease in the amount of
glutathione in the midbrain. The best explanation for this theory
is which of the following?
a. DNA synthesis requires glutathione for optimal development.
b. Dopamine synthesis requires glutathione to prevent free
radical production.
,c. Free radicals produced via dopamine synthesis are neutralized
by glutathione.
d. Glutathione is needed for entry of dopamine into the cerebral
circulation.
C
Which of the following is(are) true regarding aging?
a. may involve an increase in autoantibodies
b. may result from damage accumulation
c. both are true
d. neither is true
C
In theories of aging, cross-linking implies which of the following?
a. The lifespan and number of times a cell can replicate are
preprogrammed.
b. The number of cell doublings is limited.
c. There is oxygen toxicity.
d. Cell permeability decreases.
,D
Mr. Forbes is being prepared for open heart surgery when he
suffers a myocardial infarction in which a large part of his left
ventricle has suffered lethal cell injury.
Mr. Forbes' CPK-MB and LDH1, enzymes associated with
myocardial cells, are significantly elevated. What is the best
explanation for this?
a. It is a sign that necrotic myocardial cells have released their
cytoplasmic contents into the blood.
b. It is a sign of reversible fatty accumulation in the myocardial
cells
c. It is a sign that the myocardial cells are undergoing
hypertrophy.
d. None of the above.
A
If a tissue specimen of myocardial cells were obtained for
examination from Mr. Forbes, which of the following findings
would indicate irreversible cell injury?
a. cellular swelling
b. decreased ATP production
, c. decreased intracellular calcium
d. dissolution of nuclear material
D
The accumulation of lactic acid that occurs with impaired energy
production results from which of the following?
a. increased intracellular glucose
b. increased anaerobic metabolism
c. decreased metabolic rate
d. increased oxidative phosphorylation
B
A mountain climber is stranded at 23,000 feet in the Swiss Alps
and has lost all his equipment and supplies in an avalanche.
Subsequently, he suffers cell injury due to impaired ATP
production. The reason for the decrease in ATP is which of the
following?
a. enzyme inhibition
b. uncoupling
c. hypoxia
