BCPS EXAM QUESTIONS AND ANSWERS
Anti htn of choice in pregnancy - Answers :methyldopa, labetolol
AC of choice in pregnancy - Answers :enox
N/v meds for pregnancy - Answers :pyridoxine, doxylamine, meclizine, dimenhydrainate
Avoid in breastfeeding - Answers :opioids, contrast (x3wks after), buproprion/varenicline
Combined hormonal contraception post partum - Answers :3 weeks if no risk factors, 6
weeks if risk factor
Early breakthrough bleeding vs late breakthrough - Answers :increase estrogen vs
increase progestin (after at least 3 month trial)
Significant reduction in birth control efficacy know from - Answers :rifampin,
anticonvulsants, lamotrigine (it is decreased by OC)
Antibiotics and OC - use backup method with . . . - Answers :don't have to have an
alternate unless pt uncomfort or has breakthrough bleeding
Standard estrogen component in combined oral contraceptives - Answers :20-34 mcg
Progestone only pills - missed pill if taken how late? - Answers :3 hours
Infertility at <35, >35 - Answers :< 35 = 1 year of trying; > 35 = 6 mo
Treatment of HSV - initial infection - Answers :acclovir 400 mg PO TID x 7-10 d (only
treats symptoms; virus doesn't go away)
Suppressive therapy for HSV infection - - Answers :acyclovir 400 mg PO BID or
valacyclovir 500 mg po daily
Gonococcal infection treamtnet - Answers :treat for chlamydia too; ceftriax 250 mg IM x
1 plus azithro
Pelvic inflammatory disease - Answers :cefotetan 2 g IV q12h or cefoxitin 2 g iv q6h +
doy - treat until clinical improvement
Bacterial vaginosis - treatments - Answers :metronidazole or clindamycin
Calculation for Risk ratio - Answers :RR = A/(A+B) / C/(C+D)
Calculation for odds ratio - Answers :OR = A/C / B/D
,Analysis used for discreet data - Answers :chi squared
Type of analysis used for continuous data - Answers :t-test, two sample if data is split
into two groups
Common tests for heterogenity in meta-analyses - Answers :x2 or cochrane Q
Calculate number needed to treat - Answers :1/absolute risk reduction (only calculate if
stastically significant difference found)
Osmolality of plasma, CNS fluid - Answers :270-300 mosm/kg; 280-300 mosm/kg
Max osmo of peripheral injections for no pain - Answers :> 900 injection pain and buring
FD&C Act of 1938 - required proof of ? - Answers :safety (thalimide)
Defauver-harris amendment of 1962 required proof of? - Answers :efficacy
Generic drug pathway act was? - Answers :Hatch-Waxman Act - Drug price competition
and patent term restoration acto f 1984
Durham-humphrey amendment of 1951 did what - Answers :established difference
between Rx and non-rx
Ssris with greatest 2D6 inhibition - Answers :fluoxetine, paroxetine (very high)
Ssris with greatest 1A2 inhibition - Answers :fluvoxamine (high), fluoxemine (med)
First line antidepressants - Answers :SSRI, SNRI, mirtaz, bupro - NOT TCA bc of
suicide potential (success)
SSRI with longest half life - Answers :fluoxetine
Activating ssris - Answers :sertraline, fluoxetine
Sedating ssris - Answers :paroxetine, fluvoxamine
Snris (names) - Answers :venlafaxine, desvenlax, duloxetine, levomilnacipran
Most common side effects of SSRI, snris - Answers :headache, GI complaints, sexual
dysfunction
SNRI with other indications - Answers :duloxetine - periph neuropathy, fibromyalgia,
muscloskeletal pain; DDI with 2D6 mes
, Side effects of mirtazapine - Answers :sedation (at low doses), weight gain, increased
appetite, constipation, asthenia
Best SSRI for pregnancy - Answers :fluoxetine, sertraline, maybe bupropion
Main treatments for bipolar - Answers :mood stabelizers: lithium, anticonvulsants (VPA,
carbamaz - not first line); 2nd gen atypicals
Lithium serum concentration goal - Answers :0.8-1, acute or 0.6-1 for maintenance -
highly renally eliminated/depend on Na concentrations
Med choices for IM acute symptom managemnet of biopolar - Answers :IM aripiprazole,
olanzapine, haldol/benztropine
Agent indicated for depression part of bipolar - Answers :lurasidone, mood stabilizers,
not antidepressants, quetiapine
Schizo diagnosis - pt must exhibit one of what three symptoms - Answers
:hallucinations, delusions, disorganized speech
Agent of choice for treatment resistant schizo? - Answers :clozapine; CI for WBC <3500
Agents to treat pseudo-parkinson from antipsychotics? - Answers :benztropine,
diphenydramine, , trihexyphenidyl
Agents to treat akathisia from antipsychotics - Answers :propanolol (lipophilic beta
blockers)
Antipsycho that does NOT develop tardive dyskinesia - Answers :clozapine (intervention
of choice)
Biggest benefit and ade with second generation antipsychotics - Answers :lower EPS,
higher metabolic syndromes
Sgas with highest weight gain - Answers :clozapine, olanzapine (sedation too, and
quetiapine)
SGA with greatest effect on qtc - Answers :ziprasadone, less weight gain
SGA with greatest risk of
Hyperprolactemia - Answers :risperidone. EPS high too
SGA with high incidence of akathesia - Answers :aripiprazole
Benzo with long half life - Answers :diazepam; has active metabolites - relies on liver
function for elimination/metabolism
Anti htn of choice in pregnancy - Answers :methyldopa, labetolol
AC of choice in pregnancy - Answers :enox
N/v meds for pregnancy - Answers :pyridoxine, doxylamine, meclizine, dimenhydrainate
Avoid in breastfeeding - Answers :opioids, contrast (x3wks after), buproprion/varenicline
Combined hormonal contraception post partum - Answers :3 weeks if no risk factors, 6
weeks if risk factor
Early breakthrough bleeding vs late breakthrough - Answers :increase estrogen vs
increase progestin (after at least 3 month trial)
Significant reduction in birth control efficacy know from - Answers :rifampin,
anticonvulsants, lamotrigine (it is decreased by OC)
Antibiotics and OC - use backup method with . . . - Answers :don't have to have an
alternate unless pt uncomfort or has breakthrough bleeding
Standard estrogen component in combined oral contraceptives - Answers :20-34 mcg
Progestone only pills - missed pill if taken how late? - Answers :3 hours
Infertility at <35, >35 - Answers :< 35 = 1 year of trying; > 35 = 6 mo
Treatment of HSV - initial infection - Answers :acclovir 400 mg PO TID x 7-10 d (only
treats symptoms; virus doesn't go away)
Suppressive therapy for HSV infection - - Answers :acyclovir 400 mg PO BID or
valacyclovir 500 mg po daily
Gonococcal infection treamtnet - Answers :treat for chlamydia too; ceftriax 250 mg IM x
1 plus azithro
Pelvic inflammatory disease - Answers :cefotetan 2 g IV q12h or cefoxitin 2 g iv q6h +
doy - treat until clinical improvement
Bacterial vaginosis - treatments - Answers :metronidazole or clindamycin
Calculation for Risk ratio - Answers :RR = A/(A+B) / C/(C+D)
Calculation for odds ratio - Answers :OR = A/C / B/D
,Analysis used for discreet data - Answers :chi squared
Type of analysis used for continuous data - Answers :t-test, two sample if data is split
into two groups
Common tests for heterogenity in meta-analyses - Answers :x2 or cochrane Q
Calculate number needed to treat - Answers :1/absolute risk reduction (only calculate if
stastically significant difference found)
Osmolality of plasma, CNS fluid - Answers :270-300 mosm/kg; 280-300 mosm/kg
Max osmo of peripheral injections for no pain - Answers :> 900 injection pain and buring
FD&C Act of 1938 - required proof of ? - Answers :safety (thalimide)
Defauver-harris amendment of 1962 required proof of? - Answers :efficacy
Generic drug pathway act was? - Answers :Hatch-Waxman Act - Drug price competition
and patent term restoration acto f 1984
Durham-humphrey amendment of 1951 did what - Answers :established difference
between Rx and non-rx
Ssris with greatest 2D6 inhibition - Answers :fluoxetine, paroxetine (very high)
Ssris with greatest 1A2 inhibition - Answers :fluvoxamine (high), fluoxemine (med)
First line antidepressants - Answers :SSRI, SNRI, mirtaz, bupro - NOT TCA bc of
suicide potential (success)
SSRI with longest half life - Answers :fluoxetine
Activating ssris - Answers :sertraline, fluoxetine
Sedating ssris - Answers :paroxetine, fluvoxamine
Snris (names) - Answers :venlafaxine, desvenlax, duloxetine, levomilnacipran
Most common side effects of SSRI, snris - Answers :headache, GI complaints, sexual
dysfunction
SNRI with other indications - Answers :duloxetine - periph neuropathy, fibromyalgia,
muscloskeletal pain; DDI with 2D6 mes
, Side effects of mirtazapine - Answers :sedation (at low doses), weight gain, increased
appetite, constipation, asthenia
Best SSRI for pregnancy - Answers :fluoxetine, sertraline, maybe bupropion
Main treatments for bipolar - Answers :mood stabelizers: lithium, anticonvulsants (VPA,
carbamaz - not first line); 2nd gen atypicals
Lithium serum concentration goal - Answers :0.8-1, acute or 0.6-1 for maintenance -
highly renally eliminated/depend on Na concentrations
Med choices for IM acute symptom managemnet of biopolar - Answers :IM aripiprazole,
olanzapine, haldol/benztropine
Agent indicated for depression part of bipolar - Answers :lurasidone, mood stabilizers,
not antidepressants, quetiapine
Schizo diagnosis - pt must exhibit one of what three symptoms - Answers
:hallucinations, delusions, disorganized speech
Agent of choice for treatment resistant schizo? - Answers :clozapine; CI for WBC <3500
Agents to treat pseudo-parkinson from antipsychotics? - Answers :benztropine,
diphenydramine, , trihexyphenidyl
Agents to treat akathisia from antipsychotics - Answers :propanolol (lipophilic beta
blockers)
Antipsycho that does NOT develop tardive dyskinesia - Answers :clozapine (intervention
of choice)
Biggest benefit and ade with second generation antipsychotics - Answers :lower EPS,
higher metabolic syndromes
Sgas with highest weight gain - Answers :clozapine, olanzapine (sedation too, and
quetiapine)
SGA with greatest effect on qtc - Answers :ziprasadone, less weight gain
SGA with greatest risk of
Hyperprolactemia - Answers :risperidone. EPS high too
SGA with high incidence of akathesia - Answers :aripiprazole
Benzo with long half life - Answers :diazepam; has active metabolites - relies on liver
function for elimination/metabolism
