Hematology & Oncology | Exam 1

Hematology & Oncology | Exam 1

Which type of cell is affected in AML? - Myeloid (myeloblasts)



Which type of cell is affected in CML? - Myeloid (mature granulocytes)



Which type of cell is affected in ALL? - Lymphoid (immature lymphocytes)



Which type of cell is affected in CLL? - Lymphoid (mature lymphocytes)



Most common age affected by AML is... - Adults

60's



Most common age affected by CML is... - Adults (rare for < 20 y/o)

Mean age: 64



Most common age affected by ALL is... - Children

Mean age: 4

Boys > Girls



Most common age affected by CLL is... - Older adults



Survival rate/life expectancy for AML is... - Dx < 65 y/o: 35%

Dx > 65 y/o: 4%

Death occurs in months



Survival rate/life expectancy for CML is... - > 5 years

, Survival rate/life expectancy for ALL is... - 98% for children

85% for adults



Survival rate/life expectancy for CLL is... - Early stages: > 15 years

Late stages: < 4 years



Signs & Symptoms of Leukemia in General - Fever, infections

Bleeding, bruising

Weakness, fatigue, SOB

Abdominal pain from enlarged liver/spleen

Anorexia, weight loss

Bone pain



S/s Specific to AML - Abrupt onset



S/s Specific to CML - May be asymptomatic



S/s specific to ALL - Painful

Lymphadenopathy

Testicular/breast pain

CNS involvement



Expected lab values in AML... - Elevated WBC

Low RBC, H&H



Marrow — excess myeloblasts



Expected lab values in CML... - Elevated WBC (> 100,000)